SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_000061 |
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Gene Symbol: | BTK |
Description: | Homo sapiens Bruton agammaglobulinemia tyrosine kinase (BTK), mRNA. |
Gene Location: | chrX(-):100604434-100641212 |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chrX:g.101349769A>C | ICGC_snv_9830 | GC8_T | [stomach][NS][carcinoma][adenocarcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-223-5p |
ctcAATACACaaaggcccc |
0 | CGUGUAUU | m7b | (m6c->m7b) | no TS | -0.182 |
0.71 |
hsa-miR-3149 |
ctcaATACAAAaaggcccc |
0 | UUUGUAUG | m7a | Disrupted | 0.008 | no TS |
4.35 |
hsa-miR-5010-3p |
ctcaatACACAAAggcccc |
0 | UUUUGUGU | m7b | Created | no TS | -0.046 |
0.01 |
hsa-miR-599 |
ctcaatACACAAaggcccc |
0 | GUUGUGUC | m6b | Created | no TS | -0.03 | No effect |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
101349769 | rs700 | A | A |
hsa-miR-3149 |
1 |
aATACAAAaaggc |
Disrupted |
N |
0.008 |
C |
hsa-miR-223-5p hsa-miR-5010-3p hsa-miR-599 |
1 1 1 |
AATACACAaaggc aatACACAAAggc aatACACAAAggc |
Created Created Created |
N N N |
-0.182 -0.046 -0.03 |