SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_001203 |
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Gene Symbol: | BMPR1B |
Description: | Homo sapiens bone morphogenetic protein receptor, type IB (BMPR1B), mRNA. |
Gene Location: | chr4(+):95679127-96079601 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.95154776A>C | COSN5581044 | RK155_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3922-5p |
caaGCCTTGAacatcgtcc |
32767 |
UCAAGGCC | m7a | (m7a->m6a) | -0.154000 | -0.002000 |
0.460000 |
|
hsa-miR-4708-3p |
caaGCCTTGCacatcgtcc |
32767 |
AGCAAGGC | m7b | (m6b->m7b) | no TS | -0.457000 |
-7.330000 |
|
hsa-miR-561-5p |
caagCCTTGAacatcgtcc |
32767 |
AUCAAGGA | m6b | Disrupted | -0.165000 | -0.054000 |
4.580000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.95154818G>T | 0_186 | Lung cancer | |||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-125a-5p |
cacctCTCAGGGAgcgacc |
19 |
UCCCUGAG | m8a | Disrupted | -0.326 | no TS | No effect | |
hsa-miR-125b-5p |
cacctCTCAGGGAgcgacc |
19 |
UCCCUGAG | m8a | Disrupted | -0.326 | no TS | No effect | |
hsa-miR-345-3p |
cacctcTCAGGGagcgacc |
20 |
GCCCUGAA | m6b | Disrupted | -0.13 | no TS |
6.5 |
|
hsa-miR-4319 |
cacctCTCAGGGAgcgacc |
19 |
UCCCUGAG | m8a | Disrupted | -0.326 | no TS |
0.03 |
|
hsa-miR-4324 |
caccTCTCAGGGagcgacc |
18 |
CCCUGAGA | m8a | Disrupted | -0.076 | no TS | No effect | |
hsa-miR-4712-3p |
cacCTCTCATggagcgacc |
19 |
AAUGAGAG | m7b | (m6b->m7b) | -0.099 | -0.162 | No effect | |
hsa-miR-4732-3p |
cacctcTCAGGGagcgacc |
20 |
GCCCUGAC | m6b | Disrupted | -0.117 | no TS |
-2.37 |
|
hsa-miR-670 |
cacctcTCAGGGAgcgacc |
20 |
GUCCCUGA | m7b | Disrupted | -0.253 | -0.155 |
0.07 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.95155206T>G | COSN7849199 | 8035603 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4717-5p |
caccccgtcGTGGCCTcct |
32767 |
UAGGCCAC | m7b | (m6c->m7b) | -0.152000 | -0.245000 |
-0.570000 |
|
hsa-miR-483-5p |
cacCCCGTCTTggcctcct |
32767 |
AAGACGGG | m8a | Disrupted | -0.145000 | no TS |
5.400000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.95155750A>G | COSN5581045 | RK145_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-624-3p |
gcatACCTTGTtttgtaca |
32767 |
CACAAGGU | m7b | Created | -0.034000 | -0.130000 |
-0.170000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.95156054T>C | COSN2051995 | RK208_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3121-3p |
ttcaCTATTTAatttatta |
32767 |
UAAAUAGA | m7a | Disrupted | 0.103000 | no TS |
-0.030000 |
|
hsa-miR-5585-3p |
ttcaCTATTCAatttatta |
32767 |
CUGAAUAG | m7b | Created | no TS | -0.001000 |
-0.030000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.95156132T>C | COSN2051996 | RK020_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4670-3p |
tttTAACTTCggagcaaca |
32767 |
UGAAGUUA | m7b | (m6b->m7b) | 0.105000 | 0.177000 | No effect | |
hsa-miR-4671-5p |
ttttaaCTTCGGagcaaca |
32767 |
ACCGAAGA | m6b | Created | no TS | -0.072000 |
-5.100000 |
|
hsa-miR-548at-5p |
tttTAACTTTggagcaaca |
32767 |
AAAAGUUA | m7b | (m7b->m6b) | 0.268000 | 0.131000 |
0.010000 |
|
hsa-miR-4670-3p |
tttTAACTTCggagcaaca |
0 | UGAAGUUA | m7b | (m6b->m7b) | 0.105 | 0.177 | No effect | |
hsa-miR-4671-5p |
ttttaaCTTCGGagcaaca |
0 | ACCGAAGA | m6b | Created | no TS | -0.072 |
-5.1 |
|
hsa-miR-548at-5p |
tttTAACTTTggagcaaca |
0 | AAAAGUUA | m7b | (m7b->m6b) | 0.268 | 0.131 |
0.01 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr4:g.95157022A>G | 6_2240 | CLL3 | Chronic lymphocytic leukaemia | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1297 |
aaTACTTGAAcgtggataa |
6 |
UUCAAGUA | m8a | (m8a->m7a) | -0.033 | -0.044 |
0.12 |
hsa-miR-26a-5p |
aaTACTTGAAcgtggataa |
6 |
UUCAAGUA | m8a | (m8a->m7a) | -0.05 | -0.06 |
0.31 |
hsa-miR-26b-5p |
aaTACTTGAAcgtggataa |
6 |
UUCAAGUA | m8a | (m8a->m7a) | -0.04 | -0.051 |
0.04 |
hsa-miR-4465 |
aaTACTTGAGcgtggataa |
6 |
CUCAAGUA | m8a | (m7a->m8a) | -0.089 | -0.095 |
0.13 |
hsa-miR-574-3p |
aatactTGAGCGTGgataa |
5 |
CACGCUCA | m8a | Created | no TS | -0.154 |
-3.18 |
hsa-miR-1297 |
aaTACTTGAAcgtggataa |
32767 |
UUCAAGUA | m8a | (m8a->m7a) | -0.033000 | -0.044000 |
0.120000 |
hsa-miR-26a-5p |
aaTACTTGAAcgtggataa |
32767 |
UUCAAGUA | m8a | (m8a->m7a) | -0.050000 | -0.060000 |
0.310000 |
hsa-miR-26b-5p |
aaTACTTGAAcgtggataa |
32767 |
UUCAAGUA | m8a | (m8a->m7a) | -0.040000 | -0.051000 |
0.040000 |
hsa-miR-4465 |
aaTACTTGAGcgtggataa |
32767 |
CUCAAGUA | m8a | (m7a->m8a) | -0.089000 | -0.095000 |
0.130000 |
hsa-miR-574-3p |
aatactTGAGCGTGgataa |
0 | CACGCUCA | m8a | Created | no TS | -0.154000 |
-3.180000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
95154814 | rs1434536 | C | C |
hsa-miR-125a-5p hsa-miR-125b-5p hsa-miR-4319 hsa-miR-4324 hsa-miR-6761-5p hsa-miR-7854-3p |
0 |
tcacctCTCAGGG tcacctCTCAGGG tcacctCTCAGGG tcaccTCTCAGGg tcacCTCTCAGgg TCACCTCtcaggg |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N |
-0.219 -0.219 -0.219 -0.076 -0.065 -0.114 |
T |
hsa-miR-345-3p hsa-miR-4766-5p hsa-miR-488-3p hsa-miR-5681a hsa-miR-6730-5p |
0 |
tcacctTTCAGGG tcacCTTTCAGgg tcaCCTTTCAggg tcaCCTTTCAggg tcACCTTTCAggg |
Created Created Created Created Created |
N N N N N |
-0.208 -0.003 -0.082 -0.024 -0.181 |
|||
95155548 | rs111971137 | - | ATTCAAAGGATCAATATTAAAT |
hsa-miR-4712-3p |
0 |
ttgacctgtgcatgcttttgatCTCTCATtcaaaggatcaatattaaataaaatt |
Unknown |
N |
-0.099 |
- |
hsa-miR-8055 |
0 |
ttgacctgtgcatgcttttgatctCTCAAAAtt |
Unknown |
N |
0.022 |
|||
95156644 | rs191224787 | C | C |
hsa-miR-3159 hsa-miR-541-5p hsa-miR-561-5p hsa-miR-6830-5p |
0 |
cgTAATCCTtgaa cgtAATCCTTgaa cgtaaTCCTTGAA cgtaaTCCTTGAa |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
0.032 0.008 -0.096 0.002 |
G |
hsa-miR-498 |
0 |
cgtaatGCTTGAA |
Created |
N |
-0.077 |
|||
95156645 | rs185854880 | C | C |
hsa-miR-3159 hsa-miR-498 hsa-miR-541-5p hsa-miR-561-5p hsa-miR-6830-5p |
0 |
gTAATCCTtgaaa gtaatcCTTGAAA gtAATCCTTgaaa gtaaTCCTTGAAa gtaaTCCTTGAaa |
Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N |
0.032 0.058 0.008 -0.096 0.002 |
A |
hsa-miR-580-5p |
0 |
gtAATCATTgaaa |
Created |
N |
0.08 |
|||
95157005 | rs73839218 | T | |||||||
A |
hsa-miR-3121-3p |
0 |
tttTCTATTTggt |
Created |
N |
0.081 |