SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_001200
Gene Symbol:	BMP2
Description:	Homo sapiens bone morphogenetic protein 2 (BMP2), mRNA.
Gene Location:	chr20(+):6748744-6760910
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Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr20:g.6779111A>T			COSN7102741		8012351		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3924	aaATACATATatatatata	32767	AUAUGUAU	m8a	(m7a->m8a)	-0.406000	-0.302000	0.010000
hsa-miR-5011-5p	aaatacataTATATATAta	32767	UAUAUAUA	m8a	(m7b->m8a)	-1.634000	-2.042000	0.050000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
6779112	rs71646302	-	-	hsa-miR-190a-3p hsa-miR-5011-5p	0	tacataaATATATAt tacataaATATATAt	Unknown Unknown	N N	-0.229 -0.042
			AT	hsa-miR-4775 hsa-miR-590-3p	0	tacatAAAATTAtatat tacaTAAAATTAtatat	Unknown Unknown	N N	-0.128 -0.147
6779120	rs183175284	A	A	hsa-miR-190a-3p hsa-miR-5011-5p	0	ATATATAtatata aTATATATAtata	Disrupted Disrupted	N N	-0.799 -0.867
			G	hsa-miR-5580-3p	0	atATATGTAtata	Created	N	-0.103
6779481	rs6140085	A	A	hsa-let-7c-3p hsa-miR-3924	0	TTGTACAtaattt ttgTACATAAttt	Disrupted Disrupted	N N	-0.138 -0.046
			C	hsa-miR-331-5p hsa-miR-6509-5p	0	ttgTACCTAAttt ttgTACCTAAttt	Created Created	N N	-0.131 -0.126

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