SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_018179
Gene Symbol:	ATF7IP
Description:	Homo sapiens activating transcription factor 7 interacting protein (ATF7IP), mRNA.
Gene Location:	chr12(+):14518610-14651697
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr12:g.14498530A>G			COSN14518776		8014573		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-125b-1-3p	acaaAACCCGaagaaataa	0	ACGGGUUA	m6b	Created	no TS	-0.283000	-8.730000
hsa-miR-3940-5p	acaaAACCCAaagaaataa	13	GUGGGUUG	m6b	Disrupted	-0.170000	no TS	3.470000
hsa-miR-4507	acaaAACCCAaagaaataa	13	CUGGGUUG	m6b	Disrupted	-0.167000	no TS	0.800000
hsa-miR-629-5p	acaAAACCCAaagaaataa	11	UGGGUUUA	m7a	(m7a->m6a)	-0.139000	no TS	-0.200000
hsa-miR-9-5p	acaaaacCCAAAGAaataa	11	UCUUUGGU	m7a	Disrupted	-0.126000	no TS	-0.020000
hsa-miR-125b-1-3p	acaaAACCCGaagaaataa	0	ACGGGUUA	m6b	Created	no TS	-0.283000	-8.730000
hsa-miR-3940-5p	acaaAACCCAaagaaataa	13	GUGGGUUG	m6b	Disrupted	-0.170000	no TS	3.470000
hsa-miR-4507	acaaAACCCAaagaaataa	13	CUGGGUUG	m6b	Disrupted	-0.167000	no TS	0.800000
hsa-miR-629-5p	acaAAACCCAaagaaataa	11	UGGGUUUA	m7a	(m7a->m6a)	-0.139000	no TS	-0.200000
hsa-miR-9-5p	acaaaacCCAAAGAaataa	11	UCUUUGGU	m7a	Disrupted	-0.126000	no TS	-0.020000
hsa-miR-125b-1-3p	acaaAACCCGaagaaataa	0	ACGGGUUA	m6b	Created	no TS	-0.283000	-8.730000
hsa-miR-3940-5p	acaaAACCCAaagaaataa	13	GUGGGUUG	m6b	Disrupted	-0.170000	no TS	3.470000
hsa-miR-4507	acaaAACCCAaagaaataa	13	CUGGGUUG	m6b	Disrupted	-0.167000	no TS	0.800000
hsa-miR-629-5p	acaAAACCCAaagaaataa	11	UGGGUUUA	m7a	(m7a->m6a)	-0.139000	no TS	-0.200000
hsa-miR-9-5p	acaaaacCCAAAGAaataa	11	UCUUUGGU	m7a	Disrupted	-0.126000	no TS	-0.020000
hsa-miR-125b-1-3p	acaaAACCCGaagaaataa	0	ACGGGUUA	m6b	Created	no TS	-0.283000	-8.730000
hsa-miR-3940-5p	acaaAACCCAaagaaataa	13	GUGGGUUG	m6b	Disrupted	-0.170000	no TS	3.470000
hsa-miR-4507	acaaAACCCAaagaaataa	13	CUGGGUUG	m6b	Disrupted	-0.167000	no TS	0.800000
hsa-miR-629-5p	acaAAACCCAaagaaataa	11	UGGGUUUA	m7a	(m7a->m6a)	-0.139000	no TS	-0.200000
hsa-miR-9-5p	acaaaacCCAAAGAaataa	11	UCUUUGGU	m7a	Disrupted	-0.126000	no TS	-0.020000
hsa-miR-125b-1-3p	acaaAACCCGaagaaataa	0	ACGGGUUA	m6b	Created	no TS	-0.283000	-8.730000
hsa-miR-3940-5p	acaaAACCCAaagaaataa	13	GUGGGUUG	m6b	Disrupted	-0.170000	no TS	3.470000
hsa-miR-4507	acaaAACCCAaagaaataa	13	CUGGGUUG	m6b	Disrupted	-0.167000	no TS	0.800000
hsa-miR-629-5p	acaAAACCCAaagaaataa	11	UGGGUUUA	m7a	(m7a->m6a)	-0.139000	no TS	-0.200000
hsa-miR-9-5p	acaaaacCCAAAGAaataa	11	UCUUUGGU	m7a	Disrupted	-0.126000	no TS	-0.020000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
14498534	rs141728087	-	AAAT	hsa-miR-6844 hsa-miR-9-5p	11 11	aaccCAAAGAAataaataa aacCCAAAGAaataaataa	Unknown Unknown	N N	-0.002 -0.002
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