SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_004028 |
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Gene Symbol: | AQP4 |
Description: | Homo sapiens aquaporin 4 (AQP4), transcript variant a, mRNA. |
Gene Location: | chr18(-):24432007-24442575 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.26853371T>C | COSN9328880 | AOCS-166-1-2 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.26853474C>A | COSN6117170 | RK193_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-135b-3p |
aaggtggtCCCTACActga |
0 | AUGUAGGG | m7b | Disrupted | -0.138000 | -0.099000 |
0.130000 |
hsa-miR-3649 |
aaggtGGTCCCTacactga |
0 | AGGGACCU | m7a | Disrupted | NA | NA |
0.680000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.26853627T>A | COSN9677245 | C0052T | [kidney][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-15a-5p |
gcatagTGCTGCTcccagg |
3 |
UAGCAGCA | m7b | Disrupted | 0.032000 | -0.001000 |
2.780000 |
hsa-miR-15b-5p |
gcatagTGCTGCTcccagg |
3 |
UAGCAGCA | m7b | Disrupted | 0.032000 | -0.001000 |
3.870000 |
hsa-miR-16-5p |
gcatagTGCTGCTcccagg |
3 |
UAGCAGCA | m7b | Disrupted | 0.042000 | -0.019000 |
2.360000 |
hsa-miR-195-5p |
gcatagTGCTGCTcccagg |
3 |
UAGCAGCA | m7b | Disrupted | 0.042000 | -0.019000 | No effect |
hsa-miR-424-5p |
gcatagTGCTGCTcccagg |
3 |
CAGCAGCA | m7b | Disrupted | 0.032000 | -0.001000 |
2.710000 |
hsa-miR-4300 |
gcatagtgcAGCTCCCAgg |
10 |
UGGGAGCU | m8a | (m7a->m8a) | -0.028000 | -0.056000 |
-4.520000 |
hsa-miR-4793-3p |
gcatAGTGCAGctcccagg |
0 | UCUGCACU | m7b | Created | no TS | 0.008000 |
-0.220000 |
hsa-miR-497-5p |
gcatagTGCTGCTcccagg |
3 |
CAGCAGCA | m7b | Disrupted | 0.051000 | -0.001000 |
5.080000 |
hsa-miR-558 |
gcatagtGCAGCTCccagg |
0 | UGAGCUGC | m7b | Created | -0.243000 | -0.267000 |
-3.740000 |
hsa-miR-5591-5p |
gcatagtgcAGCTCCCAgg |
10 |
UGGGAGCU | m8a | (m7a->m8a) | -0.038000 | -0.088000 |
-1.170000 |
hsa-miR-920 |
gcatagtgcAGCTCCCagg |
10 |
GGGGAGCU | m7b | (m6b->m7b) | -0.024000 | -0.046000 |
-3.120000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.26854140T>A | COSN9328881 | AOCS-126-1-5 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-126-5p |
acttccAATAATagcattc |
2 |
CAUUAUUA | m6b | Created | 0.002000 | 0.198000 | No effect |
hsa-miR-4795-3p |
acttccAATAATAgcattc |
2 |
AUAUUAUU | m7b | Created | -0.050000 | 0.193000 |
-0.010000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.26854472G>A | COSN7462675 | 8035567 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3187-3p |
tcagggggcATGGCCAcac |
0 | UUGGCCAU | m7b | (m6b->m7b) | no TS | 0.081000 |
-2.990000 |
hsa-miR-4529-5p |
tcagggggcATGGCCacac |
0 | AGGCCAUC | m6b | Created | no TS | 0.027000 |
-0.010000 |
hsa-miR-4701-5p |
tcagggggcGTGGCCAcac |
5 |
UUGGCCAC | m7b | (m7b->m6b) | -0.216000 | -0.267000 | No effect |
hsa-miR-588 |
tcagggggcGTGGCCAcac |
5 |
UUGGCCAC | m7b | (m7b->m6b) | -0.197000 | -0.267000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.26855485T>G | COSN1204417 | HX13T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |