SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_000038
Gene Symbol: APC
Description: Homo sapiens adenomatous polyposis coli (APC), transcript variant 3, mRNA.
Gene Location: chr5(+):112073555-112181936
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Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr5:g.112844565T>A COSN15594436 C0098T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3134 gagTCCATCAaacatcata
 0 UGAUGGAU m7a (m6a->m7a) no TS -0.137000 -0.320000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.112845056A>G COSN2060706 RK075_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-607 gcctctTTTGAAagcttat
 4
 GUUCAAAU m6b Created -0.015000 0.086000 No effect
hsa-miR-607 gcctctTTTGAAagcttat
 0 GUUCAAAU m6b Created -0.015 0.086 No effect

Mutation Mutation ID Sample Name Cancer Type
chr5:g.112845300C>G COSN5157620 PD3945a [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1915-5p caatGCAAGGagcctagca
 0 ACCUUGCC m6b Created no TS -0.075000 -15.510000
hsa-miR-3929 caatgcaagCAGCCTagca
 0 GAGGCUGA m6b Disrupted -0.051000 no TS 0.020000
hsa-miR-4327 caaTGCAAGCagcctagca
 0 GGCUUGCA m7b (m7b->m6b) -0.213000 no TS 5.430000
hsa-miR-4419b caatgcaagCAGCCTagca
 0 GAGGCUGA m6b Disrupted -0.054000 no TS No effect
hsa-miR-4448 caatgcAAGGAGCCtagca
 0 GGCUCCUU m8a Created no TS -0.062000 -3.110000
hsa-miR-4478 caatgcaagCAGCCTagca
 0 GAGGCUGA m6b Disrupted -0.047000 no TS 0.040000
hsa-miR-502-5p caatGCAAGGAgcctagca
 0 AUCCUUGC m7b Created no TS -0.101000 -2.450000
hsa-miR-604 caatgcaaGCAGCCTagca
 0 AGGCUGCG m7a Disrupted NA NA 6.050000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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