SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_000035 |
---|---|
Gene Symbol: | ALDOB |
Description: | Homo sapiens aldolase B, fructose-bisphosphate (ALDOB), mRNA. |
Gene Location: | chr9(-):104182841-104198062 |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.101420658A>G | COSN14797838 | CHC205T | [liver][NS][carcinoma][hepatocellular_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-138-2-3p |
gggttaaGAAATAGtgctt |
1 |
GCUAUUUC | m7b | Disrupted | -0.171000 | no TS |
0.120000 |
|
hsa-miR-3675-3p |
gggttaAGAGATagtgctt |
0 | CAUCUCUA | m6b | Created | no TS | -0.104000 |
-2.740000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.101421026G>A | COSN15409833 | 0064_CRUK_PC_0064_T1_DNA | [prostate][NS][carcinoma][adenocarcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-382-3p |
atgtaGAATGATTttgagc |
0 | AAUCAUUC | m8a | Disrupted | -0.175000 | -0.033000 |
0.380000 |
|
hsa-miR-944 |
atgtagAATAATTTtgagc |
0 | AAAUUAUU | m8a | Created | no TS | 0.015000 |
-0.040000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.101421264T>C | COSN2302053 | RK184_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-219-1-3p |
ctTCAACTCTtgctagtca |
2 |
AGAGUUGA | m8a | (m8a->m7b) | -0.143000 | -0.116000 |
0.220000 |
|
hsa-miR-4433-3p |
cttcaACTCCTGctagtca |
0 | ACAGGAGU | m7b | Created | no TS | -0.122000 |
-1.350000 |
|
hsa-miR-451b |
cttcaacTCTTGCTAgtca |
1 |
UAGCAAGA | m8a | Disrupted | -0.234000 | -0.061000 |
1.430000 |
|
hsa-miR-4690-5p |
cttcaactCCTGCTagtca |
0 | GAGCAGGC | m6b | Created | no TS | -0.110000 |
-2.280000 |
|
hsa-miR-4722-5p |
cttcaaCTCCTGCtagtca |
0 | GGCAGGAG | m7b | Created | no TS | -0.197000 |
-2.400000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.101421373T>A | COSN2302054 | RK051_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-22-3p |
accttcaGCAGCTatcggg |
0 | AAGCUGCC | m6b | Created | no TS | -0.148000 |
-0.400000 |
|
hsa-miR-424-5p |
accttcaGCTGCTatcggg |
2 |
CAGCAGCA | m6b | Disrupted | -0.127000 | no TS |
1.584000 |
|
hsa-miR-4524a-5p |
accttcaGCTGCTATcggg |
2 |
AUAGCAGC | m8a | Disrupted | -0.205000 | no TS |
1.450000 |
|
hsa-miR-4524b-5p |
accttcaGCTGCTATcggg |
2 |
AUAGCAGC | m8a | Disrupted | -0.195000 | no TS |
0.500000 |
|
hsa-miR-497-5p |
accttcaGCTGCTatcggg |
2 |
CAGCAGCA | m6b | Disrupted | -0.127000 | no TS |
4.670000 |
|
hsa-miR-646 |
accttcAGCTGCTatcggg |
2 |
AAGCAGCU | m7b | Disrupted | -0.278000 | no TS |
1.510000 |
|
hsa-miR-93-3p |
acctTCAGCAGctatcggg |
0 | ACUGCUGA | m7b | Created | no TS | -0.158000 |
0.030000 |
|
hsa-miR-22-3p |
accttcaGCAGCTatcggg |
0 | AAGCUGCC | m6b | Created | no TS | -0.148 |
-0.4 |
|
hsa-miR-424-5p |
accttcaGCTGCTatcggg |
0 | CAGCAGCA | m6b | Disrupted | -0.127 | no TS |
1.584 |
|
hsa-miR-4524a-5p |
accttcaGCTGCTATcggg |
0 | AUAGCAGC | m8a | Disrupted | -0.205 | no TS |
1.45 |
|
hsa-miR-4524b-5p |
accttcaGCTGCTATcggg |
0 | AUAGCAGC | m8a | Disrupted | -0.195 | no TS |
0.5 |
|
hsa-miR-497-5p |
accttcaGCTGCTatcggg |
0 | CAGCAGCA | m6b | Disrupted | -0.127 | no TS |
4.67 |
|
hsa-miR-646 |
accttcAGCTGCTatcggg |
0 | AAGCAGCU | m7b | Disrupted | -0.278 | no TS |
1.51 |
|
hsa-miR-93-3p |
acctTCAGCAGctatcggg |
0 | ACUGCUGA | m7b | Created | no TS | -0.158 |
0.03 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.101421388C>A | COSN2302055 | RK051_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-369-3p |
ataaaTATTATataaacct |
1 |
AAUAAUAC | m6b | Created | -0.014000 | 0.005000 |
-1.190000 |
|
hsa-miR-374a-5p |
ataaaTATTATAtaaacct |
1 |
UUAUAAUA | m7b | Created | -0.122000 | -0.175000 |
-1.980000 |
|
hsa-miR-374b-5p |
ataaaTATTATATaaacct |
1 |
AUAUAAUA | m8a | Created | -0.122000 | -0.175000 |
-2.250000 |
|
hsa-miR-410 |
ataaataTTATATaaacct |
0 | AAUAUAAC | m6b | Created | no TS | 0.031000 |
-2.560000 |
|
hsa-miR-5692b |
ataaATATTATataaacct |
1 |
AAUAAUAU | m7b | Created | -0.116000 | -0.168000 |
-0.080000 |
|
hsa-miR-5692c |
ataaATATTATataaacct |
1 |
AAUAAUAU | m7b | Created | -0.116000 | -0.168000 |
-0.060000 |
|
hsa-miR-369-3p |
ataaaTATTATataaacct |
0 | AAUAAUAC | m6b | Created | -0.014 | 0.005 |
-1.19 |
|
hsa-miR-374a-5p |
ataaaTATTATAtaaacct |
0 | UUAUAAUA | m7b | Created | -0.122 | -0.175 |
-1.98 |
|
hsa-miR-374b-5p |
ataaaTATTATATaaacct |
0 | AUAUAAUA | m8a | Created | -0.122 | -0.175 |
-2.25 |
|
hsa-miR-410 |
ataaataTTATATaaacct |
0 | AAUAUAAC | m6b | Created | no TS | 0.031 |
-2.56 |
|
hsa-miR-5692b |
ataaATATTATataaacct |
0 | AAUAAUAU | m7b | Created | -0.116 | -0.168 |
-0.08 |
|
hsa-miR-5692c |
ataaATATTATataaacct |
0 | AAUAAUAU | m7b | Created | -0.116 | -0.168 |
-0.06 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.101421740C>T | COSN14876520 | CHC205T | [liver][NS][carcinoma][hepatocellular_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3125 |
cttTTCCTCTAatcctgga |
5 |
UAGAGGAA | m8a | Created | -0.060000 | -0.396000 | No effect | |
hsa-miR-3159 |
cttttcctcTAATCCTgga |
0 | UAGGAUUA | m7b | (m6b->m7b) | no TS | -0.096000 |
-0.050000 |
|
hsa-miR-3916 |
cttTTCCTCTaatcctgga |
5 |
AAGAGGAA | m7b | (m6c->m7b) | -0.060000 | -0.407000 |
-2.350000 |
|
hsa-miR-3928 |
cttTTCCTCCaatcctgga |
0 | GGAGGAAC | m7a | (m7a->m6b) | NA | NA | No effect | |
hsa-miR-765 |
ctttTCCTCCAatcctgga |
2 |
UGGAGGAG | m7a | Disrupted | -0.165000 | no TS |
0.020000 |
|
hsa-miR-766-5p |
cttTTCCTCCaatcctgga |
2 |
AGGAGGAA | m7b | (m7b->m6c) | -0.432000 | no TS |
2.030000 |
|
hsa-miR-877-5p |
ctttTCCTCTAatcctgga |
1 |
GUAGAGGA | m7b | Created | -0.255000 | -0.662000 |
-0.460000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.101421745T>C | COSN1370905 | HCC89T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3153 |
agcaaCTTTCCCtccaatc |
0 | GGGGAAAG | m7b | Created | no TS | -0.147000 |
-1.480000 |
|
hsa-miR-3928 |
agcaacttTTCCTCCaatc |
0 | GGAGGAAC | m7a | Disrupted | NA | NA | No effect | |
hsa-miR-5584-5p |
agcaacTTTCCCTccaatc |
0 | CAGGGAAA | m7b | Created | no TS | -0.080000 |
-0.010000 |
|
hsa-miR-765 |
agcaactttTCCTCCAatc |
2 |
UGGAGGAG | m7a | (m7a->m6a) | -0.165000 | no TS |
0.020000 |
|
hsa-miR-766-5p |
agcaacttTTCCTCCaatc |
2 |
AGGAGGAA | m7b | Disrupted | -0.432000 | no TS |
8.620000 |
|
hsa-miR-3153 |
agcaaCTTTCCCtccaatc |
0 | GGGGAAAG | m7b | Created | no TS | -0.147000 |
-1.480000 |
|
hsa-miR-3928 |
agcaacttTTCCTCCaatc |
0 | GGAGGAAC | m7a | Disrupted | NA | NA | No effect | |
hsa-miR-5584-5p |
agcaacTTTCCCTccaatc |
0 | CAGGGAAA | m7b | Created | no TS | -0.080000 |
-0.010000 |
|
hsa-miR-765 |
agcaactttTCCTCCAatc |
2 |
UGGAGGAG | m7a | (m7a->m6a) | -0.165000 | no TS |
0.020000 |
|
hsa-miR-766-5p |
agcaacttTTCCTCCaatc |
2 |
AGGAGGAA | m7b | Disrupted | -0.432000 | no TS |
8.620000 |
|
hsa-miR-3153 |
agcaaCTTTCCCtccaatc |
0 | GGGGAAAG | m7b | Created | no TS | -0.147 |
-1.48 |
|
hsa-miR-3928 |
agcaacttTTCCTCCaatc |
0 | GGAGGAAC | m7a | Disrupted | NA | NA | No effect | |
hsa-miR-5584-5p |
agcaacTTTCCCTccaatc |
0 | CAGGGAAA | m7b | Created | no TS | -0.08 |
-0.01 |
|
hsa-miR-765 |
agcaactttTCCTCCAatc |
0 | UGGAGGAG | m7a | (m7a->m6a) | -0.165 | no TS |
0.02 |
|
hsa-miR-766-5p |
agcaacttTTCCTCCaatc |
0 | AGGAGGAA | m7b | Disrupted | -0.432 | no TS |
8.62 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.101421754A>G | COSN1370906 | HCC11T | [liver][NS][carcinoma][hepatocellular_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-204-5p |
ctgAAAGGGAgcaactttt |
1 |
UUCCCUUU | m7b | (m7b->m6c) | -0.133000 | no TS |
0.400000 |
|
hsa-miR-211-5p |
ctgAAAGGGAgcaactttt |
1 |
UUCCCUUU | m7b | (m7b->m6c) | -0.124000 | no TS | No effect | |
hsa-miR-4287 |
ctgaAAGGGAGcaactttt |
1 |
UCUCCCUU | m7b | Disrupted | -0.185000 | no TS |
-0.200000 |
|
hsa-miR-4313 |
ctgaaAGGGGGCaactttt |
0 | AGCCCCCU | m7b | Created | no TS | -0.584000 |
-9.010000 |
|
hsa-miR-4469 |
ctgaaAGGGAGCaactttt |
0 | GCUCCCUC | m7a | Disrupted | NA | NA | No effect | |
hsa-miR-4685-3p |
ctgaAAGGGAGcaactttt |
1 |
UCUCCCUU | m7b | Disrupted | -0.232000 | no TS | No effect | |
hsa-miR-204-5p |
ctgAAAGGGAgcaactttt |
1 |
UUCCCUUU | m7b | (m7b->m6c) | -0.133000 | no TS |
0.400000 |
|
hsa-miR-211-5p |
ctgAAAGGGAgcaactttt |
1 |
UUCCCUUU | m7b | (m7b->m6c) | -0.124000 | no TS | No effect | |
hsa-miR-4287 |
ctgaAAGGGAGcaactttt |
1 |
UCUCCCUU | m7b | Disrupted | -0.185000 | no TS |
-0.200000 |
|
hsa-miR-4313 |
ctgaaAGGGGGCaactttt |
0 | AGCCCCCU | m7b | Created | no TS | -0.584000 |
-9.010000 |
|
hsa-miR-4469 |
ctgaaAGGGAGCaactttt |
0 | GCUCCCUC | m7a | Disrupted | NA | NA | No effect | |
hsa-miR-4685-3p |
ctgaAAGGGAGcaactttt |
1 |
UCUCCCUU | m7b | Disrupted | -0.232000 | no TS | No effect | |
hsa-miR-204-5p |
ctgAAAGGGAgcaactttt |
0 | UUCCCUUU | m7b | (m7b->m6c) | -0.133 | no TS |
0.4 |
|
hsa-miR-211-5p |
ctgAAAGGGAgcaactttt |
0 | UUCCCUUU | m7b | (m7b->m6c) | -0.124 | no TS | No effect | |
hsa-miR-4287 |
ctgaAAGGGAGcaactttt |
0 | UCUCCCUU | m7b | Disrupted | -0.185 | no TS |
-0.2 |
|
hsa-miR-4313 |
ctgaaAGGGGGCaactttt |
0 | AGCCCCCU | m7b | Created | no TS | -0.584 |
-9.01 |
|
hsa-miR-4469 |
ctgaaAGGGAGCaactttt |
0 | GCUCCCUC | m7a | Disrupted | NA | NA | No effect | |
hsa-miR-4685-3p |
ctgaAAGGGAGcaactttt |
0 | UCUCCCUU | m7b | Disrupted | -0.232 | no TS | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr9:g.101421776T>C | COSN9461343 | 8068595 | [pancreas][NS][carcinoid-endocrine_tumour][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-28-3p |
tccagtgctTCTAGTagga |
0 | CACUAGAU | m6b | Disrupted | -0.082000 | no TS |
0.680000 |
hsa-miR-28-5p |
tccagtGCTCCTagtagga |
0 | AAGGAGCU | m6b | Created | no TS | -0.156000 | No effect |
hsa-miR-708-5p |
tccagtGCTCCTagtagga |
0 | AAGGAGCU | m6b | Created | no TS | -0.160000 |
-0.140000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
101420960 | rs181650438 | T | |||||||
C |
hsa-miR-451b |
0 |
tTCTTGCTcaagt |
Created |
N |
-0.132 |
|||
101421740 | rs4577 | C | C |
hsa-miR-4443 hsa-miR-6515-5p hsa-miR-6894-5p hsa-miR-7154-3p hsa-miR-765 hsa-miR-766-5p |
2 2 2 2 2 2 |
ttCCTCCAAtcct ttCCTCCAAtcct tTCCTCCAatcct tTCCTCCAatcct tTCCTCCAatcct TTCCTCCAatcct |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N |
-0.18 -0.168 -0.188 -0.196 -0.165 -0.432 |
T |
hsa-miR-3125 hsa-miR-3159 hsa-miR-3916 hsa-miR-6859-5p hsa-miR-6866-5p hsa-miR-877-5p |
2 2 2 2 2 2 |
TTCCTCTAatcct ttcctcTAATCCT TTCCTCTAatcct TTCCTCTAatcct ttCCTCTAAtcct tTCCTCTAAtcct |
Created Created Created Created Created Created |
N N N N N N |
-0.336 -0.096 -0.347 -0.368 -0.154 -0.407 |
|||
101421755 | rs28580764 | G | G |
hsa-miR-204-5p hsa-miR-211-5p hsa-miR-4287 hsa-miR-4685-3p hsa-miR-6772-3p hsa-miR-6832-3p hsa-miR-7106-3p |
1 1 1 1 2 1 1 |
gAAAGGGAgcaac gAAAGGGAgcaac gaAAGGGAGcaac gaAAGGGAGcaac gaaagGGAGCAAc gAAAGGGAgcaac gaaAGGGAGCAac |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N |
-0.133 -0.124 -0.185 -0.232 -0.179 -0.079 -0.533 |
A |
hsa-miR-2115-5p hsa-miR-3977 hsa-miR-516a-3p hsa-miR-516b-3p hsa-miR-7162-5p |
2 2 1 1 1 |
gaaaGGAAGCAac gaaagGAAGCAAc gaaAGGAAGCAac gaaAGGAAGCAac gaaAGGAAGCAac |
Created Created Created Created Created |
N N N N N |
-0.169 -0.117 -0.418 -0.418 -0.45 |
|||
101421756 | rs183809646 | G | G |
hsa-miR-204-5p hsa-miR-211-5p hsa-miR-4287 hsa-miR-4685-3p hsa-miR-6772-3p hsa-miR-6832-3p hsa-miR-7106-3p |
1 1 1 1 2 1 1 |
tgAAAGGGAgcaa tgAAAGGGAgcaa tgaAAGGGAGcaa tgaAAGGGAGcaa tgaaagGGAGCAA tgAAAGGGAgcaa tgaaAGGGAGCAa |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N |
-0.133 -0.124 -0.185 -0.232 -0.179 -0.079 -0.533 |
A |
hsa-miR-130b-5p hsa-miR-4753-3p hsa-miR-5691 hsa-miR-6805-3p |
1 1 2 2 |
tGAAAGAGAgcaa tgAAAGAGAgcaa tgaaagAGAGCAA tgaaagAGAGCAA |
Created Created Created Created |
N N N N |
-0.207 -0.055 -0.126 -0.133 |