SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
  Home Search Help Download  

PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_000027
Gene Symbol: AGA
Description: Homo sapiens aspartylglucosaminidase (AGA), transcript variant 1, mRNA.
Gene Location: chr4(-):178351928-178363657
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr4:g.177431231C>T COSN9018677 AOCS-167-13-9 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4477a ttggttttaCTTAATAttc
 1
 CUAUUAAG m7b (m7b->m6b) -0.036000 0.003000 0.020000
hsa-miR-5692a ttggttTTATTTaatattc
 10
 CAAAUAAU m6b Created 0.042000 0.127000 -1.190000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.177431381A>G COSN1292351 HCC89T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-125b-1-3p attaAACCCGaaaggaatc
 0 ACGGGUUA m6b Created no TS -0.260000 -6.910000
hsa-miR-3940-5p attaAACCCAaaaggaatc
 2
 GUGGGUUG m6b Disrupted -0.158000 no TS 4.500000
hsa-miR-4507 attaAACCCAaaaggaatc
 2
 CUGGGUUG m6b Disrupted -0.161000 no TS 6.200000
hsa-miR-629-5p atTAAACCCAaaaggaatc
 2
 UGGGUUUA m8a (m8a->m7b) -0.329000 -0.188000 0.070000
hsa-miR-125b-1-3p attaAACCCGaaaggaatc
 0 ACGGGUUA m6b Created no TS -0.260000 -6.910000
hsa-miR-3940-5p attaAACCCAaaaggaatc
 2
 GUGGGUUG m6b Disrupted -0.158000 no TS 4.500000
hsa-miR-4507 attaAACCCAaaaggaatc
 2
 CUGGGUUG m6b Disrupted -0.161000 no TS 6.200000
hsa-miR-629-5p atTAAACCCAaaaggaatc
 2
 UGGGUUUA m8a (m8a->m7b) -0.329000 -0.188000 0.070000
hsa-miR-125b-1-3p attaAACCCGaaaggaatc
 0 ACGGGUUA m6b Created no TS -0.26 -6.91
hsa-miR-3940-5p attaAACCCAaaaggaatc
 0 GUGGGUUG m6b Disrupted -0.158 no TS 4.5
hsa-miR-4507 attaAACCCAaaaggaatc
 0 CUGGGUUG m6b Disrupted -0.161 no TS 6.2
hsa-miR-629-5p atTAAACCCAaaaggaatc
 0 UGGGUUUA m8a (m8a->m7b) -0.329 -0.188 0.07

Mutation Mutation ID Sample Name Cancer Type
chr4:g.177431651G>A 7_176 NA [upper_aerodigestive_tract][mouth][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4274 gctgaaaaGACTGCTcact
 7
 CAGCAGUC m7b Created no TS -0.28 -1.08

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
177431525 rs1061814 A A hsa-miR-5692a
10
 TTATTTAaccttt
 Disrupted
N
 0.042

Genome Browser