SomamiR DB

SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only All 6mer or longer seed matches

PolymiRTS Database

RefSeq ID:	NM_001177800
Gene Symbol:	ADIPOQ
Description:	Homo sapiens adiponectin, C1Q and collagen domain containing (ADIPOQ), transcript variant 1, mRNA.
Gene Location:	chr3(+):186560462-186576252
Browse Associations
Browse Pathways

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186854956T>G			COSN1273472		HCC65T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-296-5p	gctattttGGGCCCactgt	0	AGGGCCCC	m6b	Created	no TS	-0.233000	-0.040000
hsa-miR-3136-3p	gctattTTGGGCCcactgt	0	UGGCCCAA	m7b	Created	no TS	-0.257000	-0.500000
hsa-miR-296-5p	gctattttGGGCCCactgt	0	AGGGCCCC	m6b	Created	no TS	-0.233000	-0.040000
hsa-miR-3136-3p	gctattTTGGGCCcactgt	0	UGGCCCAA	m7b	Created	no TS	-0.257000	-0.500000
hsa-miR-296-5p	gctattttGGGCCCactgt	0	AGGGCCCC	m6b	Created	no TS	-0.233	-0.04
hsa-miR-3136-3p	gctattTTGGGCCcactgt	0	UGGCCCAA	m7b	Created	no TS	-0.257	-0.5

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186855241C>T			COSN6758140		RK308_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1275	taaaaccTCCCCCAagcag	0	GUGGGGGA	m7b	Disrupted	-0.291000	no TS	4.140000
hsa-miR-30c-1-3p	taaaaccTCTCCCAagcag	2	CUGGGAGA	m7b	Created	-0.158000	-0.377000	-0.030000
hsa-miR-30c-2-3p	taaaaccTCTCCCAagcag	2	CUGGGAGA	m7b	Created	-0.172000	-0.391000	-0.240000
hsa-miR-4525	taaaaccTCCCCCaagcag	1	GGGGGGAU	m6b	Disrupted	-0.171000	no TS	1.800000
hsa-miR-4665-5p	taaaaccTCCCCCAagcag	0	CUGGGGGA	m7b	Disrupted	-0.291000	no TS	2.960000
hsa-miR-4723-5p	taaaacCTCCCCCAagcag	0	UGGGGGAG	m8a	Disrupted	-0.368000	no TS	4.120000
hsa-miR-5010-5p	taaaaccTCCCCCaagcag	1	AGGGGGAU	m6b	Disrupted	-0.168000	no TS	0.020000
hsa-miR-5698	taaaacCTCCCCCAagcag	0	UGGGGGAG	m8a	Disrupted	-0.378000	no TS	0.070000
hsa-miR-625-5p	taaaaccTCCCCCaagcag	1	AGGGGGAA	m6b	Disrupted	-0.161000	no TS	0.050000

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186855652G>A			ICGC_9AD47E68-2A78-11E2-8335-12FD496BB9B8		CPCG_0102_Pr_P_P2		ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1272	tggggttTCATCATgttgg	0	GAUGAUGA	m7b	Created	no TS	-0.013	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186855653T>C			ICGC_9AD4834A-2A78-11E2-8335-12FD496BB9B8		CPCG_0102_Pr_P_P2		ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186856156T>C			COSN1273473		HCC87T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3173-3p	aagccattgCCTCCTTgag	0	AAAGGAGG	m7b	(m6c->m7b)	-0.167000	-0.142000	No effect
hsa-miR-3612	aagccatTGCCTCCTtgag	2	AGGAGGCA	m8a	Created	-0.076000	-0.158000	-0.030000
hsa-miR-4428	aagccattgTCTCCTTGag	0	CAAGGAGA	m8a	(m8a->m7b)	0.106000	0.023000	No effect
hsa-miR-4695-5p	aagccattGCCTCCTtgag	1	CAGGAGGC	m7b	Created	-0.328000	-0.410000	No effect
hsa-miR-650	aagccatTGCCTCCTtgag	2	AGGAGGCA	m8a	Created	-0.072000	-0.154000	No effect
hsa-miR-3173-3p	aagccattgCCTCCTTgag	0	AAAGGAGG	m7b	(m6c->m7b)	-0.167	-0.142	No effect
hsa-miR-3612	aagccatTGCCTCCTtgag	0	AGGAGGCA	m8a	Created	-0.076	-0.158	-0.03
hsa-miR-4428	aagccattgTCTCCTTGag	0	CAAGGAGA	m8a	(m8a->m7b)	0.106	0.023	No effect
hsa-miR-4695-5p	aagccattGCCTCCTtgag	0	CAGGAGGC	m7b	Created	-0.328	-0.41	0.26
hsa-miR-650	aagccatTGCCTCCTtgag	0	AGGAGGCA	m8a	Created	-0.072	-0.154	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186856500A>G			ICGC_9AD48822-2A78-11E2-8335-12FD496BB9B8		CPCG_0102_Pr_P_P2		ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1251	tgccagGCTAGAGTgcagt	1	ACUCUAGC	m8a	Disrupted	0.051	0.015	No effect
hsa-miR-508-5p	tgccaggCTGGAGTgcagt	0	UACUCCAG	m7b	Created	-0.172	-0.07	-0.15
hsa-miR-5684	tgccaggCTAGAGTgcagt	1	AACUCUAG	m7b	Disrupted	0.053	no TS	1.25
hsa-miR-766-3p	tgccagGCTGGAGTgcagt	0	ACUCCAGC	m8a	Created	-0.22	-0.189	-1.31

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186856561T>C			ICGC_9AD48CF0-2A78-11E2-8335-12FD496BB9B8		CPCG_0102_Pr_P_P2		ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-298	agcgattCTTCTGCctcag	1	AGCAGAAG	m7b	Disrupted	0.069	no TS	1.6
hsa-miR-4722-5p	agcgattCTCCTGCCtcag	0	GGCAGGAG	m8a	Created	-0.194	-0.187	-0.6
hsa-miR-4768-3p	agcgatTCTCCTGcctcag	0	CCAGGAGA	m7b	Created	-0.546	-0.471	-0.06
hsa-miR-940	agcgattctCCTGCCTcag	0	AAGGCAGG	m7b	(m6c->m7b)	-0.177	-0.184	-0.14

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186856636A>G			COSN4913456		CPCG_0184_Pr_P_P1		[prostate][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4684-5p	tttttaGTAGAGAcagggt	2	CUCUCUAC	m7b	Created	-0.083000	-0.077000	-2.480000
hsa-miR-511	tttttagtAAAGACAgggt	1	GUGUCUUU	m7b	Disrupted	0.100000	no TS	0.030000
hsa-miR-4684-5p	tttttaGTAGAGAcagggt	0	CUCUCUAC	m7b	Created	-0.083	-0.077	-2.48
hsa-miR-511	tttttagtAAAGACAgggt	0	GUGUCUUU	m7b	Disrupted	0.1	no TS	0.03

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186856654A>G			ICGC_7449B15A-2A78-11E2-96E7-04FD496BB9B8		CPCG_0102_Pr_P_P1		ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-5583-3p	tttcaCCATATTggccagg	1	GAAUAUGG	m7b	Disrupted	0.144	no TS	0.01

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186857442T>C			COSN6758141		RK122_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186857626C>T			COSN9539931		AOCS-109-1-X		[ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1266	caaaagaggCCTGAGagaa	0	CCUCAGGG	m6b	Disrupted	-0.106000	-0.068000	No effect
hsa-miR-2682-3p	caaAAGAGGCctgagagaa	0	CGCCUCUU	m7b	(m7b->m6b)	-0.143000	-0.058000	No effect
hsa-miR-4330	caaaagaggTCTGAGagaa	0	CCUCAGAU	m6b	Created	no TS	-0.031000	-3.080000
hsa-miR-4518	caaaagaggCCTGAGagaa	0	GCUCAGGG	m6b	Disrupted	-0.099000	-0.061000	No effect
hsa-miR-4650-5p	caaaagAGGCCTGAgagaa	1	UCAGGCCU	m8a	Disrupted	-0.221000	no TS	No effect
hsa-miR-4757-5p	caaaAGAGGCCTgagagaa	0	AGGCCUCU	m8a	Disrupted	-0.272000	-0.113000	-0.200000

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186857630A>G			COSN7628566		PCSI_0048_Pa_P_526		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1266	agaggCCTGAGagaaactg	0	CCUCAGGG	m6b	Disrupted	-0.106000	-0.068000	No effect
hsa-miR-150-5p	agaggccTGGGAGAaactg	0	UCUCCCAA	m7a	Created	no TS	-0.045000	-2.770000
hsa-miR-1915-3p	agaggCCTGGGagaaactg	0	CCCCAGGG	m6b	Created	no TS	-0.077000	No effect
hsa-miR-2116-3p	agaggccTGGGAGaaactg	0	CCUCCCAU	m6b	Created	no TS	-0.060000	-2.960000
hsa-miR-4518	agaggCCTGAGagaaactg	0	GCUCAGGG	m6b	Disrupted	-0.099000	-0.061000	No effect
hsa-miR-4650-5p	agAGGCCTGAgagaaactg	1	UCAGGCCU	m8a	(m8a->m7a)	-0.221000	-0.091000	-0.020000
hsa-miR-4713-5p	agaggccTGGGAGAAactg	0	UUCUCCCA	m8a	Created	no TS	-0.121000	-0.820000
hsa-miR-4726-3p	agaggCCTGGGagaaactg	0	ACCCAGGU	m6b	Created	no TS	-0.094000	-2.450000
hsa-miR-4768-5p	agaggcctGAGAGAAactg	2	AUUCUCUC	m7b	Disrupted	-0.014000	0.021000	No effect
hsa-miR-532-3p	agaggccTGGGAGaaactg	0	CCUCCCAC	m6b	Created	no TS	-0.055000	-4.240000
hsa-miR-629-3p	agaggcctGGGAGAAactg	0	GUUCUCCC	m7b	Created	no TS	-0.107000	-1.970000

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186858011G>A			COSN6573293		ICGC_MB60		[central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4712-3p	cagaCTCTCATTctgtggc	0	AAUGAGAG	m8a	Created	no TS	-0.128000	-0.020000

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186858250A>G			COSN5041832		HX21T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4284	attacaggcGTGAGCCatc	1	GGGCUCAC	m7b	(m6c->m7b)	-0.131000	-0.343000	No effect
hsa-miR-532-5p	attacAGGCATGagccatc	0	CAUGCCUU	m7a	Disrupted	NA	NA	0.080000

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.186858452T>C			COSN1936780		RK029_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3065-5p	taataaaaTTGTTGAattt	0	UCAACAAA	m7a	Disrupted	-0.014000	0.113000	0.190000
hsa-miR-421	taataaaatTGTTGAattt	0	AUCAACAG	m6b	Disrupted	-0.177000	no TS	3.450000
hsa-miR-590-3p	taaTAAAATTgttgaattt	2	UAAUUUUA	m7b	(m7b->m6b)	0.055000	0.165000	No effect
hsa-miR-3065-5p	taataaaaTTGTTGAattt	0	UCAACAAA	m7a	Disrupted	-0.014000	0.113000	0.190000
hsa-miR-421	taataaaatTGTTGAattt	0	AUCAACAG	m6b	Disrupted	-0.177000	no TS	3.450000
hsa-miR-590-3p	taaTAAAATTgttgaattt	2	UAAUUUUA	m7b	(m7b->m6b)	0.055000	0.165000	No effect
hsa-miR-3065-5p	taataaaaTTGTTGAattt	0	UCAACAAA	m7a	Disrupted	-0.014	0.113	0.19
hsa-miR-421	taataaaatTGTTGAattt	0	AUCAACAG	m6b	Disrupted	-0.177	no TS	3.45
hsa-miR-590-3p	taaTAAAATTgttgaattt	2	UAAUUUUA	m7b	(m7b->m6b)	0.055	0.165	No effect

**Germline mutations in target sites of miRNAs in somatic mutation table**
Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
186854740	rs201402829	G	G	hsa-miR-1227-5p hsa-miR-185-3p hsa-miR-4260 hsa-miR-4283 hsa-miR-4489 hsa-miR-4675 hsa-miR-4687-3p hsa-miR-4741	2 2 2 2 2 4 3 4	caaacaGCCCCAA caaaCAGCCCCAa caaacaGCCCCAA caaacAGCCCCAa caaacAGCCCCAa caaACAGCCCcaa caAACAGCCccaa caaACAGCCCcaa	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N N N	-0.219 -0.544 -0.297 -0.222 -0.235 -0.257 -0.175 -0.267
186854740	rs201402829	G	C	hsa-miR-1275 hsa-miR-4665-5p hsa-miR-609 hsa-miR-6747-5p hsa-miR-6751-5p hsa-miR-6752-5p hsa-miR-6803-5p hsa-miR-6835-5p hsa-miR-6842-5p hsa-miR-7109-5p hsa-miR-7110-5p	2 2 3 4 2 2 2 2 2 2 2	caaacaCCCCCAA caaacaCCCCCAA caAACACCCccaa caaACACCCCcaa caaacACCCCCAA caaaCACCCCCAa caaacACCCCCAA caaacACCCCCAa caaaCACCCCCAa caaacaCCCCCAA caaaCACCCCCAa	Created Created Created Created Created Created Created Created Created Created Created	N N N N N N N N N N N	-0.202 -0.199 -0.177 -0.283 -0.496 -0.568 -0.475 -0.249 -0.547 -0.21 -0.547
186854793	rs188947568	A	A	hsa-miR-5692a	2	TTATTTAgttgga	Disrupted	N	-0.016
186854793	rs188947568	A	T	hsa-miR-3065-5p	7	ttatTTTGTTGga	Created	N	-0.122
186854973	rs199943987	G	G	hsa-miR-4433-3p hsa-miR-4459 hsa-miR-4711-5p hsa-miR-4768-3p	3 3 4 3	tCTCCTGAtgctc tCTCCTGAtgctc tctcCTGATGCtc TCTCCTGAtgctc	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.114 -0.084 -0.18 -0.25
186854973	rs199943987	G	T	hsa-miR-3173-3p hsa-miR-4428 hsa-miR-6891-5p	3 3 3	tCTCCTTAtgctc TCTCCTTAtgctc tCTCCTTAtgctc	Created Created Created	N N N	-0.081 -0.226 -0.071
186854974	rs184535507	A	A	hsa-miR-4433-3p hsa-miR-4459 hsa-miR-4711-5p hsa-miR-4768-3p	3 3 1 3	CTCCTGAtgctca CTCCTGAtgctca ctcCTGATGCtca CTCCTGAtgctca	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.114 -0.084 -0.18 -0.122
186854974	rs184535507	A
186855540	rs189760873	C	C	hsa-miR-3173-3p hsa-miR-4434 hsa-miR-4516 hsa-miR-4695-5p hsa-miR-5703 hsa-miR-6770-5p hsa-miR-6891-5p	2 4 4 2 5 5 2	agCCTCCTTctcc agcctcCTTCTCC agcctcCTTCTCC aGCCTCCTtctcc agcctcCTTCTCC agcctCCTTCTCc agCCTCCTTctcc	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N N	-0.003 0.02 0.02 -0.11 0.02 -0.028 -0.041
186855540	rs189760873	C	T	hsa-miR-583	2	agCCTCTTTctcc	Created	N	0.063
186855579	rs200960156	T	C	hsa-miR-6746-5p hsa-miR-6771-5p	1 1	gcCTCCCGAgtag gcCTCCCGAgtag	Created Created	N N	-0.12 -0.126
186855579	rs200960156	T	T	hsa-miR-3664-3p hsa-miR-4433-3p hsa-miR-4459 hsa-miR-4695-5p hsa-miR-4768-3p hsa-miR-510-5p hsa-miR-512-5p	1 1 1 1 1 1 1	gccTCCTGAGtag gcCTCCTGAgtag gCCTCCTGAgtag GCCTCCTgagtag gcCTCCTGAgtag gcctCCTGAGTAg gcctcCTGAGTAg	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N N	-0.017 -0.017 -0.14 -0.132 -0.014 -0.166 -0.018
186855641	rs202034095	A
186855641	rs202034095	A	G	hsa-miR-3675-3p hsa-miR-4684-5p	2 2	agTAGAGATgggg aGTAGAGAtgggg	Created Created	N N	0.029 -0.073
186855700	rs201119230	C	C	hsa-miR-363-5p hsa-miR-3656 hsa-miR-6087 hsa-miR-6745	2 1 1 2	TCCACCCgcctcg tcCACCCGCctcg tccacCCGCCTCg TCCACCCgcctcg	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.048 -0.123 -0.086 -0.048
186855700	rs201119230	C	T	hsa-miR-1827 hsa-miR-3665 hsa-miR-4736 hsa-miR-6808-5p hsa-miR-6893-5p hsa-miR-940	1 1 1 1 1 1	tccacCTGCCTCg tcCACCTGCctcg tccACCTGCCtcg tccaCCTGCCTcg tccaCCTGCCTcg tccaCCTGCCTcg	Created Created Created Created Created Created	N N N N N N	No Change -0.033 -0.016 -0.033 -0.024 -0.024
186855734	rs6414520	G	A	hsa-miR-214-5p hsa-miR-6514-3p hsa-miR-6811-3p hsa-miR-6847-3p	0	ACAGGCAtgagcc ACAGGCAtgagcc ACAGGCAtgagcc acaggCATGAGCc	Created Created Created Created	N N N N	-0.047 -0.086 -0.047 -0.027
186855734	rs6414520	G	G	hsa-miR-4284	0	acaggcGTGAGCC	Disrupted	N	-0.083
186855914	rs185270715	C	C	hsa-miR-5089-5p hsa-miR-6871-5p	4 3	tgAATCCCAtatc tgaaTCCCATAtc	Disrupted Disrupted	N N	-0.019 -0.034
186855914	rs185270715	C	T	hsa-miR-4712-3p hsa-miR-5186	3 4	tgaaTCTCATAtc tgAATCTCAtatc	Created Created	N N	0.024 0.011
186856157	rs199944090	C	C	hsa-miR-4428	1	cattgTCTCCTTg	Disrupted	N	0.083
186856157	rs199944090	C	T	hsa-miR-4261 hsa-miR-4496 hsa-miR-651-3p hsa-miR-6830-5p	1 1 1 5	catTGTTTCCttg cattGTTTCCTtg cattgTTTCCTTg cattgtTTCCTTG	Created Created Created Created	N N N N	0.032 0.028 0.158 0.002
186856163	rs111856964	G	G	hsa-miR-561-5p hsa-miR-6830-5p hsa-miR-888-5p	4 4 4	cTCCTTGAgtacc cTCCTTGAgtacc ctccTTGAGTAcc	Disrupted Disrupted Disrupted	N N N	0.068 0.044 0.108
186856163	rs111856964	G	A	hsa-miR-3173-3p hsa-miR-4428 hsa-miR-4477b hsa-miR-6891-5p	4 4 4 4	CTCCTTAagtacc CTCCTTAagtacc cTCCTTAAgtacc CTCCTTAagtacc	Created Created Created Created	N N N N	0.05 -0.005 0.118 0.054
186856191	rs201773400	G	G	hsa-miR-4695-5p hsa-miR-5008-5p	4 4	gactggGCCTCCT gactGGGCCTCct	Disrupted Disrupted	N N	-0.02 -0.095
186856191	rs201773400	G	T	hsa-miR-4751 hsa-miR-7154-3p	4 4	gactGGTCCTCct gactgGTCCTCCt	Created Created	N N	-0.097 -0.037
186856559	rs201817952	C	C	hsa-miR-298	1	gcgattCTTCTGC	Disrupted	N	0.069
186856559	rs201817952	C	G	hsa-miR-589-3p	1	gcgatTGTTCTGc	Created	N	0.115
186856636	rs201347029	A	A	hsa-miR-511-5p hsa-miR-6830-3p	1 1	ttagtAAAGACAg ttagtAAAGACAg	Disrupted Disrupted	N N	0.1 0.114
186856636	rs201347029	A	G	hsa-miR-4684-5p hsa-miR-593-3p hsa-miR-6818-3p hsa-miR-6895-3p	1 1 1 1	ttaGTAGAGAcag ttagtAGAGACAg ttagtAGAGACAg ttagtAGAGACAg	Created Created Created Created	N N N N	0.006 0.055 0.034 0.051
186856697	rs4686804	G	G	hsa-miR-3612 hsa-miR-4443 hsa-miR-6087 hsa-miR-650 hsa-miR-7112-5p	2 2 1 2 0	ctgcccGCCTCCA ctgcccGCCTCCA ctgcCCGCCTCca ctgcccGCCTCCA CTGCCCGcctcca	Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N	-0.048 -0.039 -0.079 -0.044 -0.102
186856697	rs4686804	G	A	hsa-miR-3689d hsa-miR-541-3p hsa-miR-6134 hsa-miR-654-5p hsa-miR-6721-5p hsa-miR-6851-5p	2 0 1 0 0 2	ctgccCACCTCCA ctGCCCACCtcca ctgcCCACCTCca ctGCCCACCtcca CTGCCCAcctcca ctgccCACCTCCA	Created Created Created Created Created Created	N N N N N N	-0.093 -0.112 -0.02 -0.112 -0.003 -0.051
186856990	rs200698610	C	C	hsa-miR-6125 hsa-miR-6850-5p	1 2	gCCTTCCGcagtg gccTTCCGCAgtg	Disrupted Disrupted	N N	-0.04 -0.034
186856990	rs200698610	C	T	hsa-miR-298 hsa-miR-3158-5p hsa-miR-4418 hsa-miR-509-3-5p hsa-miR-509-5p	2 2 1 1 1	gcCTTCTGCAgtg gcctTCTGCAGtg gccttCTGCAGTg gccttCTGCAGTg gccttCTGCAGTg	Created Created Created Created Created	N N N N N	0.09 0.015 -0.016 -0.035 -0.016
186857046	rs200710189	T	C	hsa-miR-149-3p hsa-miR-4728-5p hsa-miR-6746-5p hsa-miR-6771-5p hsa-miR-6785-5p hsa-miR-6883-5p	0	CCCTCCCgatatc CCCTCCCgatatc ccCTCCCGAtatc ccCTCCCGAtatc CCCTCCCgatatc CCCTCCCgatatc	Created Created Created Created Created Created	N N N N N N	-0.081 -0.081 -0.086 -0.077 -0.081 -0.09
186857046	rs200710189	T	T	hsa-miR-144-5p hsa-miR-3074-3p hsa-miR-4433-3p hsa-miR-4459 hsa-miR-4768-3p hsa-miR-4779	1 0 0 0 0 0	ccctccTGATATC ccctcCTGATATc ccCTCCTGAtatc cCCTCCTGAtatc ccCTCCTGAtatc CCCTCCTgatatc	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N	0.013 0.11 0.014 -0.045 0.014 -0.083
186857080	rs200026218	G
186857080	rs200026218	G	A	hsa-miR-3201 hsa-miR-4712-3p hsa-miR-4791	1 1 1	gctctCATATCCc gCTCTCATAtccc gctctCATATCCc	Created Created Created	N N N	0.062 0.092 0.034
186857522	rs200335620	C	C	hsa-miR-3173-3p hsa-miR-4428 hsa-miR-6891-5p	0	ggtgggCTCCTTA ggtgggCTCCTTA ggtgggCTCCTTA	Disrupted Disrupted Disrupted	N N N	0.029 0.023 0.036
186857522	rs200335620	C	T	hsa-miR-3914 hsa-miR-651-3p	2 2	ggtgGGTTCCTta ggtgggTTCCTTA	Created Created	N N	-0.065 0.09
186857527	rs201012021	C	T	hsa-miR-3173-3p hsa-miR-3607-3p hsa-miR-3686 hsa-miR-4428 hsa-miR-6891-5p	0	gCTCCTTAcagaa gctccTTACAGAa gctccTTACAGAA gCTCCTTAcagaa gCTCCTTAcagaa	Created Created Created Created Created	N N N N N	0.029 0.072 0.089 0.023 0.036
186857527	rs201012021	C	C	hsa-miR-1294 hsa-miR-3150b-3p hsa-miR-4316 hsa-miR-4677-3p hsa-miR-4679 hsa-miR-4689 hsa-miR-4784 hsa-miR-6858-5p	0	gctCCTCACAgaa gCTCCTCAcagaa gctCCTCACAgaa gctcCTCACAGAa gctccTCACAGAa gCTCCTCAcagaa gCTCCTCAcagaa gCTCCTCAcagaa	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N N N	-0.023 -0.003 -0.021 -0.039 0.01 0.02 -0.01 0.011
186857626	rs201474196	C	C	hsa-miR-1266-5p hsa-miR-1972 hsa-miR-2682-3p hsa-miR-3664-3p hsa-miR-4518 hsa-miR-4650-5p hsa-miR-4757-5p hsa-miR-6744-3p hsa-miR-6781-3p	6 1 0 6 6 1 0 0 0	aagaggCCTGAGA aagaGGCCTGAga AAGAGGCctgaga aagaggCCTGAGA aagaggCCTGAGA aagAGGCCTGAga aAGAGGCCtgaga aAGAGGCCtgaga AAGAGGCctgaga	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N N N N	-0.038 -0.099 -0.085 -0.029 -0.038 -0.221 -0.159 -0.159 -0.123
186857626	rs201474196	C	T	hsa-miR-4330 hsa-miR-6821-3p	6 0	aagaggTCTGAGA aAGAGGTCtgaga	Created Created	N N	-0.031 -0.128
186857632	rs78177548	A	A	hsa-miR-1266-5p hsa-miR-3664-3p hsa-miR-4518 hsa-miR-4768-5p hsa-miR-6809-3p hsa-miR-6833-3p hsa-miR-6873-3p	6 6 6 4 4 4 5	CCTGAGAgaaact CCTGAGAgaaact CCTGAGAgaaact cctGAGAGAAAct cctgAGAGAAAct cctGAGAGAAAct cctGAGAGAAact	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N N	-0.038 -0.029 -0.038 -0.035 0.048 -0.056 -0.009
186857632	rs78177548	A	G	hsa-miR-4446-5p hsa-miR-4755-5p hsa-miR-5006-3p hsa-miR-642a-5p	4 4 4 5	cctgAGGGAAAct cctgAGGGAAAct cctgAGGGAAAct cctGAGGGAAact	Created Created Created Created	N N N N	0.016 -0.02 -0.013 -0.054
186858250	rs34422369	A	A	hsa-miR-214-5p hsa-miR-6514-3p hsa-miR-6811-3p hsa-miR-6847-3p	2 2 2 2	ACAGGCAtgagcc ACAGGCAtgagcc ACAGGCAtgagcc acaggCATGAGCc	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.141 -0.209 -0.141 -0.162
186858250	rs34422369	A	G	hsa-miR-4284	2	acaggcGTGAGCC	Created	N	-0.212
186858254	rs187638504	G	G	hsa-miR-24-3p hsa-miR-4284 hsa-miR-6847-3p	1 1 1	gcaTGAGCCAtca gcaTGAGCCAtca gCATGAGCcatca	Disrupted Disrupted Disrupted	N N N	-0.108 -0.119 -0.162
186858254	rs187638504	G	A	hsa-miR-1206 hsa-miR-218-2-3p hsa-miR-8069	1 1 1	gCATGAACcatca gcatGAACCATca gcatgAACCATCA	Created Created Created	N N N	-0.1 -0.136 -0.254

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Somatic mutations that impact miRNA target sites

Germline mutations in target sites of miRNAs in somatic mutation table

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