SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_000668 |
---|---|
Gene Symbol: | ADH1B |
Description: | Homo sapiens alcohol dehydrogenase 1B (class I), beta polypeptide (ADH1B), mRNA. |
Gene Location: | chr4(-):100227526-100242572 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.99306522A>T | COSN7720589 | 8033414 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-323a-3p |
tagacaTAATGTaaaatag |
0 | CACAUUAC | m6b | Created | no TS | -0.056000 |
0.600000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.99306716A>G | COSN5547188 | RK172_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4422 |
cctgtgttaATGCTTTgtt |
4 |
AAAAGCAU | m7b | (m7b->m6b) | -0.301000 | -0.174000 |
-1.770000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.99306893A>T | COSN5049897 | HX34T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-137 |
aacaccttaAGCAATAtat |
3 |
UUAUUGCU | m7b | (m7b->m6b) | -0.160000 | no TS |
1.860000 |
|
hsa-miR-25-3p |
aacaccttaTGCAATatat |
2 |
CAUUGCAC | m6b | Created | -0.086000 | -0.154000 |
-1.330000 |
|
hsa-miR-363-3p |
aacaccttaTGCAATatat |
2 |
AAUUGCAC | m6b | Created | -0.096000 | -0.168000 |
-1.220000 |
|
hsa-miR-367-3p |
aacaccttaTGCAATatat |
2 |
AAUUGCAC | m6b | Created | -0.107000 | -0.179000 |
-0.010000 |
|
hsa-miR-4720-3p |
aacacCTTAAGCAatatat |
2 |
UGCUUAAG | m8a | Disrupted | -0.227000 | no TS |
7.380000 |
|
hsa-miR-4804-3p |
aacaccTTAAGCAatatat |
2 |
UGCUUAAC | m7a | Disrupted | -0.067000 | no TS |
5.370000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.99307331C>A | COSN1975941 | RK041_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-627 |
atAGACTCACatttacaag |
3 |
GUGAGUCU | m8a | (m8a->m7b) | -0.150000 | -0.287000 |
0.120000 |
|
hsa-miR-627 |
atAGACTCACatttacaag |
0 | GUGAGUCU | m8a | (m8a->m7b) | -0.15 | -0.287 |
0.12 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.99307358G>T | COSN9004893 | 8051720 | [pancreas][NS][carcinoid-endocrine_tumour][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3140-3p |
ggggtAAAAGCTagggtaa |
0 | AGCUUUUG | m7a | Disrupted | NA | NA | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.99307404C>A | COSN9897244 | C0057T | [kidney][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4282 |
cactgtcgAAATTTTcctt |
0 | UAAAAUUU | m7b | Created | no TS | 0.110000 |
-0.010000 |
|
hsa-miR-513a-3p |
cactgtcGAAATTTtcctt |
2 |
UAAAUUUC | m7b | Created | 0.109000 | 0.149000 |
-1.110000 |
|
hsa-miR-513c-3p |
cactgtcGAAATTTtcctt |
2 |
UAAAUUUC | m7b | Created | 0.109000 | 0.149000 |
-1.610000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.99307540T>A | COSN5049898 | HX21T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-224-5p |
cctGTGACTTcttgcattt |
3 |
CAAGUCAC | m7b | (m7b->m6c) | -0.164000 | no TS |
0.900000 |
|
hsa-miR-5697 |
cctgtgaCTACTTGcattt |
0 | UCAAGUAG | m7b | Created | no TS | -0.163000 |
-3.770000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.99307541T>G | COSN5049899 | HX21T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-224-5p |
tcctGTGACTTcttgcatt |
3 |
CAAGUCAC | m7b | Disrupted | -0.164000 | no TS |
0.900000 |
|
hsa-miR-4696 |
tcctgtgacGTCTTGCAtt |
6 |
UGCAAGAC | m8a | (m7a->m8a) | -0.123000 | -0.339000 |
-4.300000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr4:g.99307796T>A | COSN15448396 | AOCS-164-1-7 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1224-5p |
agccTCCTCAaccctacaa |
0 | GUGAGGAC | m6b | Created | no TS | -0.105000 |
0.650000 |
hsa-miR-197-5p |
agcctccTCTACCCtacaa |
2 |
CGGGUAGA | m7b | Disrupted | -0.212000 | no TS |
4.000000 |
hsa-miR-296-3p |
agcctcctCAACCCTacaa |
0 | GAGGGUUG | m7b | Created | no TS | -0.462000 |
-9.260000 |
hsa-miR-3132 |
agcctccTCTACCCtacaa |
2 |
UGGGUAGA | m7b | Disrupted | -0.221000 | no TS |
4.000000 |
hsa-miR-3150b-3p |
agcCTCCTCAaccctacaa |
0 | UGAGGAGA | m7a | (m6b->m7a) | no TS | -0.127000 |
-1.000000 |
hsa-miR-3916 |
agccTCCTCTaccctacaa |
4 |
AAGAGGAA | m6b | Disrupted | -0.084000 | no TS |
0.010000 |
hsa-miR-4451 |
agcctcCTCTACCctacaa |
2 |
UGGUAGAG | m7b | Disrupted | -0.194000 | no TS |
8.710000 |
hsa-miR-4689 |
agcCTCCTCAAccctacaa |
0 | UUGAGGAG | m8a | Created | no TS | -0.290000 |
-10.230000 |
hsa-miR-4784 |
agcCTCCTCAaccctacaa |
0 | UGAGGAGA | m7a | (m6b->m7a) | no TS | -0.137000 |
-1.000000 |
hsa-miR-877-5p |
agccTCCTCTACcctacaa |
4 |
GUAGAGGA | m8a | Disrupted | -0.108000 | no TS |
1.200000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
99307285 | rs3211503 | C | |||||||
T |
hsa-miR-4282 hsa-miR-5009-3p |
3 22 |
AAATTTTttagga aaatttTTTAGGA |
Created Created |
N N |
0.119 -0.047 |