SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_139056
Gene Symbol:	ADAMTS16
Description:	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 16 (ADAMTS16), mRNA.
Gene Location:	chr5(+):5140442-5320412
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr5:g.5319174C>T			COSN7946786		8067242		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3064-3p	aagtgcctgTGTGGCAcag	2	UUGCCACA	m7b	(m6c->m7b)	-0.155000	-0.350000	-3.690000
hsa-miR-4269	aaGTGCCTGCgtggcacag	1	GCAGGCAC	m8a	(m8a->m7a)	-0.217000	-0.245000	-1.140000

Mutation			Mutation ID		Sample Name		Cancer Type
chr5:g.5319650C>A			COSN2110324		RK064_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3945	tccaggaggATGCCCaggc	0	AGGGCAUA	m6b	Created	no TS	-0.072000	-0.200000
hsa-miR-4253	tccaggaggATGCCCaggc	0	AGGGCAUG	m6b	Created	no TS	-0.059000	-6.000000
hsa-miR-5196-3p	tccagGAGGATGcccaggc	0	UCAUCCUC	m7b	Created	no TS	-0.034000	-0.070000

Mutation			Mutation ID		Sample Name		Cancer Type
chr5:g.5320097C>T			0_205				Prostate cancer
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3613-3p	ttttTTTTTTGgtgagtct	0	ACAAAAAA	m7b	Created	no TS	-0.036	-2.6

Mutation			Mutation ID		Sample Name		Cancer Type
chr5:g.5320098G>C			COSN1316979		HX12T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3148	tttTTTTTCCgtgagtctg	0	UGGAAAAA	m7b	(m6b->m7b)	no TS	-0.050000	-0.540000
hsa-miR-4798-3p	ttttttttcCGTGAGTctg	0	AACUCACG	m7b	(m6c->m7b)	no TS	-0.218000	2.900000
hsa-miR-3148	tttTTTTTCCgtgagtctg	0	UGGAAAAA	m7b	(m6b->m7b)	no TS	-0.05	-0.54
hsa-miR-4798-3p	ttttttttcCGTGAGTctg	0	AACUCACG	m7b	(m6c->m7b)	no TS	-0.218	2.9

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
5320097	rs199942396	C
			T	hsa-miR-3613-3p hsa-miR-6511a-3p hsa-miR-6511b-3p	1 1 1	tTTTTTTGgtgag ttttttTGGTGAG ttttttTGGTGAG	Created Created Created	N N N	-0.036 -0.227 -0.227

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