SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_003501
Gene Symbol:	ACOX3
Description:	Homo sapiens acyl-CoA oxidase 3, pristanoyl (ACOX3), transcript variant 2, mRNA.
Gene Location:	chr4(-):8368008-8442452
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Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr4:g.8366340A>C			COSN14477536		8057700		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-139-3p	gggcaattcCGTCTCCaac	0	GGAGACGC	m7a	(m6a->m7a)	NA	NA	-8.420000
hsa-miR-4499	gggcaatTCAGTCTccaac	3	AAGACUGA	m7b	Disrupted	-0.126000	no TS	No effect
hsa-miR-4680-3p	gggcAATTCAGtctccaac	3	UCUGAAUU	m7b	Disrupted	-0.012000	no TS	0.270000
hsa-miR-873-3p	gggcaattCAGTCTCCaac	3	GGAGACUG	m8a	Disrupted	-0.198000	no TS	4.620000
hsa-miR-139-3p	gggcaattcCGTCTCCaac	0	GGAGACGC	m7a	(m6a->m7a)	NA	NA	-8.420000
hsa-miR-4499	gggcaatTCAGTCTccaac	3	AAGACUGA	m7b	Disrupted	-0.126000	no TS	No effect
hsa-miR-4680-3p	gggcAATTCAGtctccaac	3	UCUGAAUU	m7b	Disrupted	-0.012000	no TS	0.270000
hsa-miR-873-3p	gggcaattCAGTCTCCaac	3	GGAGACUG	m8a	Disrupted	-0.198000	no TS	4.620000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
8366733	rs12701	-	G	hsa-miR-20a-3p	0	agaAATGCAGAtg	Unknown	N	-0.284
			T	hsa-miR-4427 hsa-miR-4680-3p hsa-miR-5187-3p	0	agaaATTCAGAtg agaAATTCAGAtg agaaATTCAGAtg	Unknown Unknown Unknown	N N N	-0.044 -0.151 -0.076

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