SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_000938
Gene Symbol: POLR2B
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr4:g.57031323G>A COSM3714885 38T [upper_aerodigestive_tract][mouth][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-423-3p gtgCCGAGCTataaa AGCUCGGU m7a Disrupted HHFCT_114689_uc003hcn.1_1_1267
hsa-miR-7705 gtgccGAGCTATaaa AAUAGCUC m7b Disrupted HHFCT_114689_uc003hcn.1_1_1267

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57031267T>A COSN5573742 RK140_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-33a-3p ggataacAACATTac CAAUGUUU m6b Created HHFCT_114689_uc003hcn.1_1_1267
hsa-miR-3668 ggataaCTACATTac AAUGUAGA m7a Disrupted HHFCT_114689_uc003hcn.1_1_1267
hsa-miR-409-3p ggataaCAACATTac GAAUGUUG m7b Created HHFCT_114689_uc003hcn.1_1_1267
hsa-miR-4781-3p ggataaCAACATTac AAUGUUGG m7a Created HHFCT_114689_uc003hcn.1_1_1267
hsa-miR-7852-3p ggataACTACATtac UAUGUAGU m7b Disrupted HHFCT_114689_uc003hcn.1_1_1267

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57030975T>C COSM326212 585276 [lung][NS][carcinoma][small_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1298-5p ccgCGAATGAtgagt UUCAUUCG m7b Disrupted HHFCT_118985_cluster-17142_23_78
hsa-miR-382-3p ccgcGAATGATgagt AAUCAUUC m7b Disrupted HHFCT_118985_cluster-17142_23_78

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57030970G>A COSM276838 T2944 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3677-3p ttgcaCCACGAatga CUCGUGGG m6b Created HHFCT_118985_cluster-17142_23_78
hsa-miR-4746-3p ttGCACCGCgaatga AGCGGUGC m7b (m7b->m6b) HHFCT_118985_cluster-17142_23_78
hsa-miR-579-5p ttgcACCGCGAatga UCGCGGUU m7a Disrupted HHFCT_118985_cluster-17142_23_78

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57030968C>T COSM4125336 TCGA-BR-6452-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4746-3p tattGCACCGCgaat AGCGGUGC m7b Disrupted HHFCT_118985_cluster-17142_23_78
hsa-miR-579-5p tattgcACCGCGAat UCGCGGUU m7a Disrupted HHFCT_118985_cluster-17142_23_78

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57030966C>T COSM4125335 TCGA-BR-8361-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-338-5p agTATTGTaccgcga AACAAUAU m6b Created HHFCT_118985_cluster-17142_23_78
hsa-miR-4746-3p agtattGCACCGCga AGCGGUGC m7b Disrupted HHFCT_118985_cluster-17142_23_78

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57030960G>T COSM1056384 TCGA-AP-A059-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-154-3p tcTATGATTattgca AAUCAUAC m7a (m6a->m7a) HHFCT_118985_cluster-17142_23_78
hsa-miR-376a-3p TCTATGATtattgca AUCAUAGA m8a Created HHFCT_118985_cluster-17142_23_78
hsa-miR-376b-3p TCTATGATtattgca AUCAUAGA m8a Created HHFCT_118985_cluster-17142_23_78
hsa-miR-487a-3p tcTATGATTattgca AAUCAUAC m7a (m6a->m7a) HHFCT_118985_cluster-17142_23_78

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57030923G>A COSM1221503 CPCG0094-F1 [prostate][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3607-5p gccttaCACATGCaa GCAUGUGA m7a Created HHFCT_118985_cluster-17142_23_78
hsa-miR-4666b gccttacACATGCAa UUGCAUGU m7b Created HHFCT_118985_cluster-17142_23_78
hsa-miR-511-3p gcctTACACATgcaa AAUGUGUA m7b Created HHFCT_118985_cluster-17142_23_78
Mutation Mutation ID Sample Name Cancer Type
chr4:g.57030922C>G COSM734033 TCGA-22-5492-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr4:g.57011083G>T COSM4169035 AA1830 [peritoneum][appendix][other][pseudomyxoma_peritonei]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-219b-5p tcagatGGACATCat AGAUGUCC m7b Disrupted HHFCT_118974_cluster-17142_11_13
hsa-miR-3171 tcagatgTACATCat AGAUGUAU m6b Created HHFCT_118974_cluster-17142_11_13
hsa-miR-3912-5p tcagATGGACATcat AUGUCCAU m8a Disrupted HHFCT_118974_cluster-17142_11_13
hsa-miR-493-5p tcagATGTACAtcat UUGUACAU m7b Created HHFCT_118974_cluster-17142_11_13

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57006930A>T COSM4917016 TCGA-ED-A7PZ-01 [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1295a atGGCCTAAaatact UUAGGCCG m7a (m7a->m6a) HHFCT_118973_cluster-17142_10_12
hsa-miR-4477b atggCCTTAAatact AUUAAGGA m6b Created HHFCT_118973_cluster-17142_10_12
hsa-miR-4717-5p aTGGCCTAaaatact UAGGCCAC m7a Disrupted HHFCT_118973_cluster-17142_10_12
hsa-miR-5704 aTGGCCTAAaatact UUAGGCCA m8a (m8a->m7a) HHFCT_118973_cluster-17142_10_12
hsa-miR-7856-5p atggCCTTAAAtact UUUUAAGG m7b Created HHFCT_118973_cluster-17142_10_12

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57006925G>T COSM587840 TCGA-38-4629-01 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1295a atctgatGGCCTAAa UUAGGCCG m7a Disrupted HHFCT_118973_cluster-17142_10_12
hsa-miR-15a-3p atctgATGGCCTaaa CAGGCCAU m7b Disrupted HHFCT_118973_cluster-17142_10_12
hsa-miR-4423-3p atctgatTGCCTAaa AUAGGCAC m6b Created HHFCT_118973_cluster-17142_10_12
hsa-miR-4529-5p atctGATGGCCTaaa AGGCCAUC m8a Disrupted HHFCT_118973_cluster-17142_10_12
hsa-miR-4717-5p atctgaTGGCCTAaa UAGGCCAC m7a Disrupted HHFCT_118973_cluster-17142_10_12
hsa-miR-5704 atctgaTGGCCTAAa UUAGGCCA m8a Disrupted HHFCT_118973_cluster-17142_10_12

Mutation Mutation ID Sample Name Cancer Type
chr4:g.56999700C>T COSM4509835 CSCC-27-T [skin][head_neck][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1301-5p ttgtgttTAGAGCat CGCUCUAG m6b Created HHFCT_118968_cluster-17142_5_9
hsa-miR-146a-3p ttgtgTTCAGAGcat CCUCUGAA m7b Disrupted HHFCT_118968_cluster-17142_5_9
hsa-miR-301a-5p ttgtgtTCAGAGCat GCUCUGAC m7a Disrupted HHFCT_118968_cluster-17142_5_9
hsa-miR-301b-5p ttgtgtTCAGAGCat GCUCUGAC m7a Disrupted HHFCT_118968_cluster-17142_5_9
hsa-miR-3194-3p ttgtgttCAGAGCat AGCUCUGC m6b Disrupted HHFCT_118968_cluster-17142_5_9
hsa-miR-4539 ttgtGTTCAGagcat GCUGAACU m6b Disrupted HHFCT_118968_cluster-17142_5_9
hsa-miR-520f-5p ttgtgTTTAGAGcat CCUCUAAA m7b Created HHFCT_118968_cluster-17142_5_9
hsa-miR-5691 ttgtgttCAGAGCAt UUGCUCUG m7b Disrupted HHFCT_118968_cluster-17142_5_9
hsa-miR-6502-5p ttgtgttTAGAGCat AGCUCUAG m6b Created HHFCT_118968_cluster-17142_5_9
hsa-miR-6805-3p ttgtgttCAGAGCAt UUGCUCUG m7b Disrupted HHFCT_118968_cluster-17142_5_9

Mutation Mutation ID Sample Name Cancer Type
chr4:g.56999691T>C COSM4125330 TCGA-BR-8487-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1272 ccaTCATCATtgtgt GAUGAUGA m7b Created HHFCT_118968_cluster-17142_5_9

Mutation Mutation ID Sample Name Cancer Type
chr4:g.56999677G>T COSM1056367 TCGA-B5-A0JY-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-137 caAGCAATAAgttcc UUAUUGCU m8a Created HHFCT_118968_cluster-17142_5_9

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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