SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: hsa_circ_0045946
Gene Symbol: TIMP2
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr17:g.78873912G>A COSM3712592 41T [skin][sun_exposed_site][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-6775-3p tgatCAGGGCCaaag AGGCCCUG m7b Disrupted HHFKP_61517_cluster-10597_23_70
hsa-miR-6822-3p tgatcAGAGCCaaag AGGCUCUA m6b Created HHFKP_61517_cluster-10597_23_70
hsa-miR-6851-3p tgatcAGGGCCAaag UGGCCCUU m7a Disrupted HHFKP_61517_cluster-10597_23_70
hsa-miR-760 tgatCAGAGCCaaag CGGCUCUG m7b Created HHFKP_61517_cluster-10597_23_70
hsa-miR-7976 tgaTCAGGGCcaaag UGCCCUGA m7b Disrupted HHFKP_61517_cluster-10597_23_70
hsa-miR-8057 tgatcAGAGCCAaag GUGGCUCU m7b Created HHFKP_61517_cluster-10597_23_70
hsa-miR-1291 tgatCAGGGCCAaag UGGCCCUG m8a Disrupted HHFKP_61517_cluster-10597_23_70
hsa-miR-3192-3p tGATCAGAGccaaag CUCUGAUC m8a (m7a->m8a) HHFKP_61517_cluster-10597_23_70
hsa-miR-328-3p tgatcAGGGCCAaag CUGGCCCU m7b Disrupted HHFKP_61517_cluster-10597_23_70

Mutation Mutation ID Sample Name Cancer Type
chr17:g.78873910C>T COSM4070228 TCGA-CG-5723-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1291 atCAGGGCCAaagcg UGGCCCUG m8a Disrupted HHFKP_61517_cluster-10597_23_70
hsa-miR-328-3p atcAGGGCCAaagcg CUGGCCCU m7b Disrupted HHFKP_61517_cluster-10597_23_70
hsa-miR-4725-5p atCAGGGTCaaagcg AGACCCUG m7b (m6b->m7b) HHFKP_61517_cluster-10597_23_70
hsa-miR-504-5p atCAGGGTCaaagcg AGACCCUG m7b (m6b->m7b) HHFKP_61517_cluster-10597_23_70
hsa-miR-6775-3p atCAGGGCCaaagcg AGGCCCUG m7b (m7b->m6b) HHFKP_61517_cluster-10597_23_70
hsa-miR-6851-3p atcAGGGCCAaagcg UGGCCCUU m7a Disrupted HHFKP_61517_cluster-10597_23_70
hsa-miR-7976 aTCAGGGCcaaagcg UGCCCUGA m7b Disrupted HHFKP_61517_cluster-10597_23_70

Mutation Mutation ID Sample Name Cancer Type
chr17:g.78870991G>C COSM4890902 OSCC-GB_00740111 [upper_aerodigestive_tract][mouth][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1237-3p agggcctCAGAAGGa UCCUUCUG m7b Created HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-1266-5p agggCCTGAGaagga CCUCAGGG m6b Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-3664-3p agggCCTGAGAagga UCUCAGGA m7a Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-4518 agggCCTGAGaagga GCUCAGGG m6b Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-4649-3p aggGCCTCAGAagga UCUGAGGC m8a Created HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-5008-5p aGGGCCTCAgaagga UGAGGCCC m8a (m7a->m8a) HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-6089 agGGCCTCagaagga GGAGGCCG m6b Created HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-7162-3p agggCCTCAGAagga UCUGAGGU m7a Created HHRBL_6763_BCBL1-2of3-SCL_10787

Mutation Mutation ID Sample Name Cancer Type
chr17:g.78870985G>A COSM4538366 CSCC-11-T [skin][head_neck][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-362-5p tgagAAGGATataga AAUCCUUG m6b Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-4659a-3p tgAGAAGAAtataga UUUCUUCU m7b (m6b->m7b) HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-4659b-3p tgAGAAGAAtataga UUUCUUCU m7b (m6b->m7b) HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-500b-5p tgagAAGGATataga AAUCCUUG m6b Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-501-5p tgagAAGGATataga AAUCCUUU m6b Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-6074 tgagaaGAATATaga GAUAUUCA m6b Created HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-6868-3p tgAGAAGGAtataga UUCCUUCU m7b (m7b->m6b) HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-6875-3p tgaGAAGAATataga AUUCUUCC m7a Created HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-942-5p tGAGAAGAatataga UCUUCUCU m7a Created HHRBL_6763_BCBL1-2of3-SCL_10787

Mutation Mutation ID Sample Name Cancer Type
chr17:g.78870963C>T COSM247835 PR-2915 [prostate][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-128-1-5p tacaCGGCCCCctcc CGGGGCCG m7b Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-128-2-5p tacaCGGCCCCCtcc GGGGGCCG m8a Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-3144-5p tacacGGTCCCCTcc AGGGGACC m8a Created HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-6805-5p tacacgGCCCCCTcc UAGGGGGC m7b Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787

Mutation Mutation ID Sample Name Cancer Type
chr17:g.78870958CT>T COSM253112 OV207 [ovary][NS][carcinoma][serous_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-151a-5p cggccccCTCCTCGgc UCGAGGAG m7b Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-151b cggccccCTCCTCGgc UCGAGGAG m7b Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-3184-5p cgGCCCCTCctcggc UGAGGGGC m7b (m6b->m7b) HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-423-5p cgGCCCCTCctcggc UGAGGGGC m7b (m6b->m7b) HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-4779 cggccCCCTCCTcggc UAGGAGGG m7b Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-6805-5p cgGCCCCCTcctcggc UAGGGGGC m7b (m7b->m6b) HHRBL_6763_BCBL1-2of3-SCL_10787

Mutation Mutation ID Sample Name Cancer Type
chr17:g.78870936C>T COSM4486264 CSCC-27-T [skin][head_neck][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3667-5p gGGGTCTTgctggac AAAGACCC m7b Created HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-451b ggggTCTTGCTggac UAGCAAGA m7b Created HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-4530 ggggtctTGCTGGac CCCAGCAG m6b Created HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-4696 gggGTCTTGCtggac UGCAAGAC m7b Created HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-4738-5p ggggtctCGCTGGac ACCAGCGC m6b Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787

Mutation Mutation ID Sample Name Cancer Type
chr17:g.78870935G>A COSM3755953 TCGA-AM-5821-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-199a-5p gggtctCACTGGacg CCCAGUGU m6b Created HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-199b-5p gggtctCACTGGacg CCCAGUGU m6b Created HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-4738-5p gggtctCGCTGGacg ACCAGCGC m6b Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-5190 gggtcTCACTGGacg CCAGUGAC m7a Created HHRBL_6763_BCBL1-2of3-SCL_10787
Mutation Mutation ID Sample Name Cancer Type
chr17:g.78870928G>A COSM4606427 Single_Sample [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr17:g.78870905C>T COSM3796170 TCGA-GU-A42R-01 [urinary_tract][bladder][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-106a-3p aatatctCATTGCAg CUGCAAUG m7b Disrupted HHRBL_6763_BCBL1-2of3-SCL_10787
hsa-miR-4662a-3p aaTATCTTattgcag AAAGAUAG m6b Created HHRBL_6763_BCBL1-2of3-SCL_10787

Mutation Mutation ID Sample Name Cancer Type
chr17:g.78857553A>G COSM4746353 HSJD_DIPG007 [central_nervous_system][brainstem][glioma][astrocytoma_Grade_IV]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1273g-5p agcctgAACCACagg GGUGGUUG m6b Disrupted HHFKP_61516_cluster-10597_22_68
hsa-miR-203a-5p agcctGAACCACagg AGUGGUUC m7b Disrupted HHFKP_61516_cluster-10597_22_68
hsa-miR-24-3p agcCTGAGCCAcagg UGGCUCAG m8a Created HHFKP_61516_cluster-10597_22_68
hsa-miR-3934-3p agCCTGAGCcacagg UGCUCAGG m7b (m6b->m7b) HHFKP_61516_cluster-10597_22_68
hsa-miR-4284 agccTGAGCCacagg GGGCUCAC m6b Created HHFKP_61516_cluster-10597_22_68
hsa-miR-4474-3p agcctgAGCCACAgg UUGUGGCU m7b Created HHFKP_61516_cluster-10597_22_68
hsa-miR-8057 agcctGAGCCACagg GUGGCUCU m7a Created HHFKP_61516_cluster-10597_22_68

Mutation Mutation ID Sample Name Cancer Type
chr17:g.78854628T>C COSN5420970 RK117_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1286 ccatcGTCCTGCAcg UGCAGGAC m8a Created HHFCT_64851_cluster-10597_11_70
hsa-miR-298 ccatcgTTCTGCacg AGCAGAAG m6b Disrupted HHFCT_64851_cluster-10597_11_70
hsa-miR-4436a ccatcGTCCTGCacg GCAGGACA m7a Created HHFCT_64851_cluster-10597_11_70
hsa-miR-4722-5p ccatcgTCCTGCacg GGCAGGAG m6b Created HHFCT_64851_cluster-10597_11_70
hsa-miR-1286 ccatcGTCCTGCAcg UGCAGGAC m8a Created HHFKP_61506_cluster-10597_11_69
hsa-miR-298 ccatcgTTCTGCacg AGCAGAAG m6b Disrupted HHFKP_61506_cluster-10597_11_69
hsa-miR-4436a ccatcGTCCTGCacg GCAGGACA m7a Created HHFKP_61506_cluster-10597_11_69
hsa-miR-4722-5p ccatcgTCCTGCacg GGCAGGAG m6b Created HHFKP_61506_cluster-10597_11_69

Mutation Mutation ID Sample Name Cancer Type
chr17:g.78853886A>T COSN1729703 RK006_C02 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3165 caacTCCACCagacc AGGUGGAU m6b Disrupted HHFCT_64849_cluster-10597_9_2181
hsa-miR-4299 caactcCACCAGacc GCUGGUGA m6b Disrupted HHFCT_64849_cluster-10597_9_2181
hsa-miR-4456 caactCCACCAGacc CCUGGUGG m7b Disrupted HHFCT_64849_cluster-10597_9_2181
hsa-miR-516b-5p caactcCTCCAGAcc AUCUGGAG m7b Created HHFCT_64849_cluster-10597_9_2181
hsa-miR-548q caactcCACCAGacc GCUGGUGC m6b Disrupted HHFCT_64849_cluster-10597_9_2181
hsa-miR-6880-5p caaCTCCACCAgacc UGGUGGAG m8a Disrupted HHFCT_64849_cluster-10597_9_2181
hsa-miR-6894-5p caacTCCTCCagacc AGGAGGAU m6b Created HHFCT_64849_cluster-10597_9_2181
hsa-miR-7154-3p caacTCCTCCagacc AGGAGGAC m6b Created HHFCT_64849_cluster-10597_9_2181
hsa-miR-765 caaCTCCTCCAgacc UGGAGGAG m8a Created HHFCT_64849_cluster-10597_9_2181
hsa-miR-766-5p caacTCCTCCagacc AGGAGGAA m6b Created HHFCT_64849_cluster-10597_9_2181
hsa-miR-8071 caacTCCACCagacc CGGUGGAC m6b Disrupted HHFCT_64849_cluster-10597_9_2181
hsa-miR-3165 caacTCCACCagacc AGGUGGAU m6b Disrupted HHFKP_61501_cluster-10597_5_652
hsa-miR-4299 caactcCACCAGacc GCUGGUGA m6b Disrupted HHFKP_61501_cluster-10597_5_652
hsa-miR-4456 caactCCACCAGacc CCUGGUGG m7b Disrupted HHFKP_61501_cluster-10597_5_652
hsa-miR-516b-5p caactcCTCCAGAcc AUCUGGAG m7b Created HHFKP_61501_cluster-10597_5_652
hsa-miR-548q caactcCACCAGacc GCUGGUGC m6b Disrupted HHFKP_61501_cluster-10597_5_652
hsa-miR-6880-5p caaCTCCACCAgacc UGGUGGAG m8a Disrupted HHFKP_61501_cluster-10597_5_652
hsa-miR-6894-5p caacTCCTCCagacc AGGAGGAU m6b Created HHFKP_61501_cluster-10597_5_652
hsa-miR-7154-3p caacTCCTCCagacc AGGAGGAC m6b Created HHFKP_61501_cluster-10597_5_652
hsa-miR-765 caaCTCCTCCAgacc UGGAGGAG m8a Created HHFKP_61501_cluster-10597_5_652
hsa-miR-766-5p caacTCCTCCagacc AGGAGGAA m6b Created HHFKP_61501_cluster-10597_5_652
hsa-miR-8071 caacTCCACCagacc CGGUGGAC m6b Disrupted HHFKP_61501_cluster-10597_5_652
hsa-miR-3165 caacTCCACCagacc AGGUGGAU m6b Disrupted HHRBL_6758_BCBL1-2of3-SCL_972
hsa-miR-4299 caactcCACCAGacc GCUGGUGA m6b Disrupted HHRBL_6758_BCBL1-2of3-SCL_972
hsa-miR-4456 caactCCACCAGacc CCUGGUGG m7b Disrupted HHRBL_6758_BCBL1-2of3-SCL_972
hsa-miR-516b-5p caactcCTCCAGAcc AUCUGGAG m7b Created HHRBL_6758_BCBL1-2of3-SCL_972
hsa-miR-548q caactcCACCAGacc GCUGGUGC m6b Disrupted HHRBL_6758_BCBL1-2of3-SCL_972
hsa-miR-6880-5p caaCTCCACCAgacc UGGUGGAG m8a Disrupted HHRBL_6758_BCBL1-2of3-SCL_972
hsa-miR-6894-5p caacTCCTCCagacc AGGAGGAU m6b Created HHRBL_6758_BCBL1-2of3-SCL_972
hsa-miR-7154-3p caacTCCTCCagacc AGGAGGAC m6b Created HHRBL_6758_BCBL1-2of3-SCL_972
hsa-miR-765 caaCTCCTCCAgacc UGGAGGAG m8a Created HHRBL_6758_BCBL1-2of3-SCL_972
hsa-miR-766-5p caacTCCTCCagacc AGGAGGAA m6b Created HHRBL_6758_BCBL1-2of3-SCL_972
hsa-miR-8071 caacTCCACCagacc CGGUGGAC m6b Disrupted HHRBL_6758_BCBL1-2of3-SCL_972

Mutation Mutation ID Sample Name Cancer Type
chr17:g.78853252C>T COSN7456351 8050939 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-338-5p aagtttATATTGTag AACAAUAU m7b Created HHFCT_64846_cluster-10597_4_3509
hsa-miR-4495 aagTTTACATTgtag AAUGUAAA m8a Disrupted HHFCT_64846_cluster-10597_4_3509
hsa-miR-338-5p aagtttATATTGTag AACAAUAU m7b Created HHFKP_61499_cluster-10597_3_1767
hsa-miR-4495 aagTTTACATTgtag AAUGUAAA m8a Disrupted HHFKP_61499_cluster-10597_3_1767
hsa-miR-338-5p aagtttATATTGTag AACAAUAU m7b Created HHKTA_8196_NM_003255|3352|3391|7.91803321247155|0.591198902543592
hsa-miR-4495 aagTTTACATTgtag AAUGUAAA m8a Disrupted HHKTA_8196_NM_003255|3352|3391|7.91803321247155|0.591198902543592
hsa-miR-338-5p aagtttATATTGTag AACAAUAU m7b Created HHKTB_2146_NM_003255|3345|3384|41.0240259901708|0.591198902543592
hsa-miR-4495 aagTTTACATTgtag AAUGUAAA m8a Disrupted HHKTB_2146_NM_003255|3345|3384|41.0240259901708|0.591198902543592

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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