SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: hsa_circ_0078296
Gene Symbol: MTHFD1L
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Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr6:g.151037098T>C COSM1545088 TCGA-91-6848-01 [lung][right_upper_lobe][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1252-3p gggtTCATTTaccct CAAAUGAG m6b Disrupted HHFKP_128663_cluster-19561_41_20
hsa-miR-3646 gggTTCATTTaccct AAAAUGAA m7b Disrupted HHFKP_128663_cluster-19561_41_20
hsa-miR-555 gggttcaCTTACCCt AGGGUAAG m7b Created HHFKP_128663_cluster-19561_41_20

Mutation Mutation ID Sample Name Cancer Type
chr6:g.151037097A>G COSM1074552 TCGA-BS-A0UJ-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1252-3p tgggtTCATTTaccc CAAAUGAG m6b Disrupted HHFKP_128663_cluster-19561_41_20
hsa-miR-3646 tgggTTCATTTaccc AAAAUGAA m7b Disrupted HHFKP_128663_cluster-19561_41_20

Mutation Mutation ID Sample Name Cancer Type
chr6:g.151037087C>T COSM4003733 SNUH_G10_S1 [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3065-3p gcataGGTGCTGggt UCAGCACC m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-4738-5p gcatagGCGCTGGgt ACCAGCGC m7b Disrupted HHFKP_128663_cluster-19561_41_20

Mutation Mutation ID Sample Name Cancer Type
chr6:g.151037086G>A COSM4160296 PTC-77C [thyroid][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4738-5p agcatagGCGCTGGg ACCAGCGC m7b Disrupted HHFKP_128663_cluster-19561_41_20
hsa-miR-4738-5p agcatagGCGCTGGg ACCAGCGC m7b Disrupted HHFKP_128663_cluster-19561_41_20

Mutation Mutation ID Sample Name Cancer Type
chr6:g.151037083T>C COSM4160294 PTC-77C [thyroid][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1914-5p gccaGCACAGGcgct CCCUGUGC m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-4728-3p gcCAGCATaggcgct CAUGCUGA m6b Disrupted HHFKP_128663_cluster-19561_41_20
hsa-miR-5008-3p gccAGCACAGGcgct CCUGUGCU m8a Created HHFKP_128663_cluster-19561_41_20
hsa-miR-6720-3p gccagcaCAGGCGCt CGCGCCUG m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-6737-3p gccAGCACAGgcgct UCUGUGCU m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-6811-3p gccagCACAGGCgct AGCCUGUG m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-7157-3p gccAGCACAGgcgct UCUGUGCU m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-1914-5p gccaGCACAGGcgct CCCUGUGC m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-4728-3p gcCAGCATaggcgct CAUGCUGA m6b Disrupted HHFKP_128663_cluster-19561_41_20
hsa-miR-5008-3p gccAGCACAGGcgct CCUGUGCU m8a Created HHFKP_128663_cluster-19561_41_20
hsa-miR-6720-3p gccagcaCAGGCGCt CGCGCCUG m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-6737-3p gccAGCACAGgcgct UCUGUGCU m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-6811-3p gccagCACAGGCgct AGCCUGUG m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-7157-3p gccAGCACAGgcgct UCUGUGCU m7b Created HHFKP_128663_cluster-19561_41_20

Mutation Mutation ID Sample Name Cancer Type
chr6:g.151037077C>T COSM4160291 PTC-77C [thyroid][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1538 gtCCGGGCCagcata CGGCCCGG m7b (m7b->m6b) HHFKP_128663_cluster-19561_41_20
hsa-miR-4728-3p gtccgggTCAGCATa CAUGCUGA m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-4745-3p gtCCGGGCCAgcata UGGCCCGG m8a Disrupted HHFKP_128663_cluster-19561_41_20
hsa-miR-4750-3p gtccGGGTCAGcata CCUGACCC m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-628-5p gtccggGTCAGCATa AUGCUGAC m8a Created HHFKP_128663_cluster-19561_41_20
hsa-miR-1538 gtCCGGGCCagcata CGGCCCGG m7b (m7b->m6b) HHFKP_128663_cluster-19561_41_20
hsa-miR-4728-3p gtccgggTCAGCATa CAUGCUGA m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-4745-3p gtCCGGGCCAgcata UGGCCCGG m8a Disrupted HHFKP_128663_cluster-19561_41_20
hsa-miR-4750-3p gtccGGGTCAGcata CCUGACCC m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-628-5p gtccggGTCAGCATa AUGCUGAC m8a Created HHFKP_128663_cluster-19561_41_20

Mutation Mutation ID Sample Name Cancer Type
chr6:g.151037073C>T COSM3366323 TCGA-B0-4813-01 [kidney][NS][carcinoma][clear_cell_renal_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1538 tgacgtCCGGGCCag CGGCCCGG m7b Disrupted HHFKP_128663_cluster-19561_41_20
hsa-miR-4745-3p tgacgtCCGGGCCAg UGGCCCGG m8a Disrupted HHFKP_128663_cluster-19561_41_20

Mutation Mutation ID Sample Name Cancer Type
chr6:g.151037069C>T COSM4160289 PTC-77C [thyroid][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3687 tcagtgaTGTCCGGg CCCGGACA m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-3913-3p tcagTGATGTCcggg AGACAUCA m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-4420 TCAGTGACgtccggg GUCACUGA m8a Disrupted HHFKP_128663_cluster-19561_41_20
hsa-miR-4442 tcagtgaTGTCCGGg GCCGGACA m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-499a-3p tcaGTGATGTccggg AACAUCAC m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-499b-3p tcaGTGATGTccggg AACAUCAC m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-3687 tcagtgaTGTCCGGg CCCGGACA m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-3913-3p tcagTGATGTCcggg AGACAUCA m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-4420 TCAGTGACgtccggg GUCACUGA m8a Disrupted HHFKP_128663_cluster-19561_41_20
hsa-miR-4442 tcagtgaTGTCCGGg GCCGGACA m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-499a-3p tcaGTGATGTccggg AACAUCAC m7b Created HHFKP_128663_cluster-19561_41_20
hsa-miR-499b-3p tcaGTGATGTccggg AACAUCAC m7b Created HHFKP_128663_cluster-19561_41_20

Mutation Mutation ID Sample Name Cancer Type
chr6:g.151015666C>T COSM3410662 TCGA-32-4208-01 [central_nervous_system][brain][glioma][astrocytoma_Grade_IV]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-6505-3p aaAGAAGTCgattcc UGACUUCU m7b (m6b->m7b) HHFKP_128657_cluster-19561_35_12
hsa-miR-6815-3p aaAGAAGCCgattcc UGGCUUCU m7b (m7b->m6b) HHFKP_128657_cluster-19561_35_12
hsa-miR-103a-2-5p aAAGAAGCcgattcc AGCUUCUU m7b Disrupted HHFKP_128657_cluster-19561_35_12
hsa-miR-6505-3p aaAGAAGTCgattcc UGACUUCU m7b (m6b->m7b) HHFKP_128657_cluster-19561_35_12
hsa-miR-6815-3p aaAGAAGCCgattcc UGGCUUCU m7b (m7b->m6b) HHFKP_128657_cluster-19561_35_12

Mutation Mutation ID Sample Name Cancer Type
chr6:g.151015635G>T COSM398833 LUAD-S01404 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-615-3p ttGGCTCGGgctgtg UCCGAGCC m7b (m7b->m6b) HHFKP_128657_cluster-19561_35_12
hsa-miR-6856-3p ttggctcGGGCTGTg UACAGCCC m7b Disrupted HHFKP_128657_cluster-19561_35_12

Mutation Mutation ID Sample Name Cancer Type
chr6:g.151009953C>T COSM1239486 ESO-859 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1538 aggCGGGCCaagtgt CGGCCCGG m6b Disrupted HHFKP_128655_cluster-19561_33_16
hsa-miR-328-3p aggcGGGCCAagtgt CUGGCCCU m6b Disrupted HHFKP_128655_cluster-19561_33_16
hsa-miR-3614-5p aggcgggCCAAGTGt CCACUUGG m7b Disrupted HHFKP_128655_cluster-19561_33_16
hsa-miR-4745-3p aggCGGGCCAagtgt UGGCCCGG m7a Disrupted HHFKP_128655_cluster-19561_33_16

Mutation Mutation ID Sample Name Cancer Type
chr6:g.151009940G>C COSM75474 TCGA-13-0890-01 [ovary][NS][carcinoma][serous_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-490-5p tgaagATCCATGGag CCAUGGAU m8a Created HHFKP_128655_cluster-19561_33_16
hsa-miR-5581-3p tgaagatGCATGGAg UUCCAUGC m7b Disrupted HHFKP_128655_cluster-19561_33_16
hsa-miR-6872-3p tgaagatGCATGGag CCCAUGCC m6b Disrupted HHFKP_128655_cluster-19561_33_16

Mutation Mutation ID Sample Name Cancer Type
chr6:g.151009929G>A COSM740609 TCGA-51-4081-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-6501-3p ggtgcgaGCTCTGaa CCAGAGCA m6b Disrupted HHFKP_128655_cluster-19561_33_16
hsa-miR-759 ggtgcgaACTCTGaa GCAGAGUG m6b Created HHFKP_128655_cluster-19561_33_16

Mutation Mutation ID Sample Name Cancer Type
chr6:g.151009927G>A COSM282910 TCGA-AA-A010-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4327 acggTGCAAGCtctg GGCUUGCA m7b Created HHFKP_128655_cluster-19561_33_16
hsa-miR-500a-3p acGGTGCAagctctg AUGCACCU m6b Created HHFKP_128655_cluster-19561_33_16

Mutation Mutation ID Sample Name Cancer Type
chr6:g.151009926C>T COSM3859114 TCGA-BR-6452-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-342-3p aacgGTGTGAGctct UCUCACAC m7b Created HHFKP_128655_cluster-19561_33_16
hsa-miR-3670 aacggtgTGAGCTCt AGAGCUCA m7b Created HHFKP_128655_cluster-19561_33_16

Mutation Mutation ID Sample Name Cancer Type
chr6:g.150990715G>T COSN14928144 LP6007544-DNA_A01 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4493 tgccttGGCCTTCca AGAAGGCC m7b Disrupted HHFKP_128647_cluster-19561_25_8
hsa-miR-4533 tgccttgTCCTTCCa UGGAAGGA m7b Created HHFKP_128647_cluster-19561_25_8
hsa-miR-4753-5p tgcctTGGCCTTcca CAAGGCCA m7b Disrupted HHFKP_128647_cluster-19561_25_8
hsa-miR-8080 tgcctTGTCCTTCca GAAGGACA m8a Created HHFKP_128647_cluster-19561_25_8

Mutation Mutation ID Sample Name Cancer Type
chr6:g.150956042G>T COSM1634568 RK072_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-181b-2-3p cgggCAGTGAaacac CUCACUGA m6b Created HPRO6_66800_G79809.1_151277174
hsa-miR-181b-3p cgggCAGTGAaacac CUCACUGA m6b Created HPRO6_66800_G79809.1_151277174
hsa-miR-4420 cgggCAGTGAaacac GUCACUGA m6b Created HPRO6_66800_G79809.1_151277174
hsa-miR-4446-5p cgggcAGGGAAAcac AUUUCCCU m7b Disrupted HPRO6_66800_G79809.1_151277174
hsa-miR-5096 cgggcaGTGAAACac GUUUCACC m7a Created HPRO6_66800_G79809.1_151277174
hsa-miR-653-3p cgggCAGTGAAacac UUCACUGG m7a Created HPRO6_66800_G79809.1_151277174
hsa-miR-670-5p cgggCAGGGAaacac GUCCCUGA m6b Disrupted HPRO6_66800_G79809.1_151277174
hsa-miR-6752-3p cgGGCAGGGAaacac UCCCUGCC m8a Disrupted HPRO6_66800_G79809.1_151277174
hsa-miR-6890-3p cgGGCAGTGaaacac CCACUGCC m7b (m6b->m7b) HPRO6_66800_G79809.1_151277174

Mutation Mutation ID Sample Name Cancer Type
chr6:g.150956035C>T COSM4424923 218 [oesophagus][middle_third][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-8069 tAACCATCgggcagg GGAUGGUU m7b Disrupted HPRO6_66800_G79809.1_151277174

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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