SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

Transcript ID: hsa_circ_0078269
Gene Symbol: MTHFD1L
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr6:g.150887950T>C COSM4703552 T3118 [large_intestine][rectum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1243 atgagcATCCAGTgg AACUGGAU m7b Disrupted HPCB1_34709_G44442.1_151209086
hsa-miR-3907 atGAGCACCcagtgg AGGUGCUC m7b (m6b->m7b) HPCB1_34709_G44442.1_151209086
hsa-miR-6741-5p atgaGCACCCAgtgg GUGGGUGC m7b Created HPCB1_34709_G44442.1_151209086
hsa-miR-6776-5p atgagCACCCAGtgg UCUGGGUG m7b Created HPCB1_34709_G44442.1_151209086
hsa-miR-1243 atgagcATCCAGTgg AACUGGAU m7b Disrupted HPCB1_34709_G44442.1_151209086
hsa-miR-3907 atGAGCACCcagtgg AGGUGCUC m7b (m6b->m7b) HPCB1_34709_G44442.1_151209086
hsa-miR-6741-5p atgaGCACCCAgtgg GUGGGUGC m7b Created HPCB1_34709_G44442.1_151209086
hsa-miR-6776-5p atgagCACCCAGtgg UCUGGGUG m7b Created HPCB1_34709_G44442.1_151209086

Mutation Mutation ID Sample Name Cancer Type
chr6:g.150887936C>T COSM3859111 TCGA-BR-6566-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-376a-3p aagggTCTATGAcaa AUCAUAGA m7b Created HPCB1_34709_G44442.1_151209086
hsa-miR-376b-3p aagggTCTATGAcaa AUCAUAGA m7b Created HPCB1_34709_G44442.1_151209086
hsa-miR-4725-5p aAGGGTCTatgacaa AGACCCUG m7a Created HPCB1_34709_G44442.1_151209086
hsa-miR-490-5p aagggTCCATGacaa CCAUGGAU m6b Disrupted HPCB1_34709_G44442.1_151209086
hsa-miR-504-5p aAGGGTCTatgacaa AGACCCUG m7a Created HPCB1_34709_G44442.1_151209086
hsa-miR-711 aaGGGTCCatgacaa GGGACCCA m6b Disrupted HPCB1_34709_G44442.1_151209086
hsa-miR-376a-3p aagggTCTATGAcaa AUCAUAGA m7b Created HPCB1_34709_G44442.1_151209086
hsa-miR-376b-3p aagggTCTATGAcaa AUCAUAGA m7b Created HPCB1_34709_G44442.1_151209086
hsa-miR-4725-5p aAGGGTCTatgacaa AGACCCUG m7a Created HPCB1_34709_G44442.1_151209086
hsa-miR-490-5p aagggTCCATGacaa CCAUGGAU m6b Disrupted HPCB1_34709_G44442.1_151209086
hsa-miR-504-5p aAGGGTCTatgacaa AGACCCUG m7a Created HPCB1_34709_G44442.1_151209086
hsa-miR-711 aaGGGTCCatgacaa GGGACCCA m6b Disrupted HPCB1_34709_G44442.1_151209086

Mutation Mutation ID Sample Name Cancer Type
chr6:g.150887856G>T COSM1487322 TCGA-C8-A1HK-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-587 caacctaTATGGAAa UUUCCAUA m7b Created HHFCT_140232_cluster-19561_2_87

Mutation Mutation ID Sample Name Cancer Type
chr6:g.150885722C>G COSM3829303 TCGA-D8-A1JA-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1305 tgaacttGTTGAAAa UUUUCAAC m7b Created HHKTB_3509_NM_015440|872|911|31.493191669222|0.857373956341409
hsa-miR-3065-5p tgaacTTGTTGAaaa UCAACAAA m7a Created HHKTB_3509_NM_015440|872|911|31.493191669222|0.857373956341409
hsa-miR-421 tgaactTGTTGAaaa AUCAACAG m6b Created HHKTB_3509_NM_015440|872|911|31.493191669222|0.857373956341409
hsa-miR-498 tgaacttCTTGAAAa UUUCAAGC m7a Disrupted HHKTB_3509_NM_015440|872|911|31.493191669222|0.857373956341409
hsa-miR-7159-5p tgaacTTGTTGAAaa UUCAACAA m8a Created HHKTB_3509_NM_015440|872|911|31.493191669222|0.857373956341409
hsa-miR-1305 tgaacttGTTGAAAa UUUUCAAC m7b Created HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-3065-5p tgaacTTGTTGAaaa UCAACAAA m7a Created HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-421 tgaactTGTTGAaaa AUCAACAG m6b Created HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-498 tgaacttCTTGAAAa UUUCAAGC m7a Disrupted HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-7159-5p tgaacTTGTTGAAaa UUCAACAA m8a Created HHRBL_12787_BCBL1-2of3-SCL_5416

Mutation Mutation ID Sample Name Cancer Type
chr6:g.150885707G>A COSM3019154 TCGA-FS-A1ZK-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4328 tgccAAAACTGtaat CCAGUUUU m7b Created HHFKP_128633_cluster-19561_11_13
hsa-miR-582-5p tgccaaAACTGTAAt UUACAGUU m8a Created HHFKP_128633_cluster-19561_11_13
hsa-miR-4328 tgccAAAACTGtaat CCAGUUUU m7b Created HHKTB_3509_NM_015440|872|911|31.493191669222|0.857373956341409
hsa-miR-582-5p tgccaaAACTGTAAt UUACAGUU m8a Created HHKTB_3509_NM_015440|872|911|31.493191669222|0.857373956341409
hsa-miR-4328 tgccAAAACTGtaat CCAGUUUU m7b Created HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-582-5p tgccaaAACTGTAAt UUACAGUU m8a Created HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-4328 tgccAAAACTGtaat CCAGUUUU m7b Created HHFKP_128633_cluster-19561_11_13
hsa-miR-582-5p tgccaaAACTGTAAt UUACAGUU m8a Created HHFKP_128633_cluster-19561_11_13
hsa-miR-4328 tgccAAAACTGtaat CCAGUUUU m7b Created HHKTB_3509_NM_015440|872|911|31.493191669222|0.857373956341409
hsa-miR-582-5p tgccaaAACTGTAAt UUACAGUU m8a Created HHKTB_3509_NM_015440|872|911|31.493191669222|0.857373956341409
hsa-miR-4328 tgccAAAACTGtaat CCAGUUUU m7b Created HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-582-5p tgccaaAACTGTAAt UUACAGUU m8a Created HHRBL_12787_BCBL1-2of3-SCL_5416

Mutation Mutation ID Sample Name Cancer Type
chr6:g.150885685T>C COSM483546 TCGA-B0-5706-01 [kidney][NS][carcinoma][clear_cell_renal_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1179 atGAATGCTTtgttt AAGCAUUC m8a Created HHFKP_128633_cluster-19561_11_13
hsa-miR-181a-5p aTGAATGTTttgttt AACAUUCA m8a (m8a->m7a) HHFKP_128633_cluster-19561_11_13
hsa-miR-181b-5p aTGAATGTTttgttt AACAUUCA m8a (m8a->m7a) HHFKP_128633_cluster-19561_11_13
hsa-miR-181c-5p aTGAATGTTttgttt AACAUUCA m8a (m8a->m7a) HHFKP_128633_cluster-19561_11_13
hsa-miR-181d-5p aTGAATGTTttgttt AACAUUCA m8a (m8a->m7a) HHFKP_128633_cluster-19561_11_13
hsa-miR-330-3p atgaaTGCTTTGttt GCAAAGCA m7b Created HHFKP_128633_cluster-19561_11_13
hsa-miR-4262 aTGAATGTtttgttt GACAUUCA m7b Disrupted HHFKP_128633_cluster-19561_11_13
hsa-miR-4422 atgaATGCTTTgttt AAAAGCAU m7b Created HHFKP_128633_cluster-19561_11_13
hsa-miR-543 atGAATGTTTtgttt AAACAUUC m8a Disrupted HHFKP_128633_cluster-19561_11_13
hsa-miR-1179 atGAATGCTTtgttt AAGCAUUC m8a Created HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-181a-5p aTGAATGTTttgttt AACAUUCA m8a (m8a->m7a) HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-181b-5p aTGAATGTTttgttt AACAUUCA m8a (m8a->m7a) HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-181c-5p aTGAATGTTttgttt AACAUUCA m8a (m8a->m7a) HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-181d-5p aTGAATGTTttgttt AACAUUCA m8a (m8a->m7a) HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-330-3p atgaaTGCTTTGttt GCAAAGCA m7b Created HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-4262 aTGAATGTtttgttt GACAUUCA m7b Disrupted HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-4422 atgaATGCTTTgttt AAAAGCAU m7b Created HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-543 atGAATGTTTtgttt AAACAUUC m8a Disrupted HHRBL_12787_BCBL1-2of3-SCL_5416

Mutation Mutation ID Sample Name Cancer Type
chr6:g.150885673T>A COSM1196595 H1703 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-27a-5p gaggggAAGCCCatg AGGGCUUA m6b Created HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-324-5p gagGGGATGCccatg CGCAUCCC m7b Disrupted HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-3945 gaggggATGCCCatg AGGGCAUA m6b Disrupted HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-4253 gaggggATGCCCatg AGGGCAUG m6b Disrupted HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-6729-3p gaGGGGATGcccatg UCAUCCCC m7b (m7b->m6b) HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-6862-5p gaggggATGCCCatg CGGGCAUG m6b Disrupted HHRBL_12787_BCBL1-2of3-SCL_5416

Mutation Mutation ID Sample Name Cancer Type
chr6:g.150885661G>A COSM4645555 LOVO [large_intestine][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-106b-3p ggaagctAGTGCGag CCGCACUG m6b Created HHFKP_128632_cluster-19561_10_7
hsa-miR-1226-3p ggaaGCTGGTGcgag UCACCAGC m7b Disrupted HHFKP_128632_cluster-19561_10_7
hsa-miR-4661-5p ggaAGCTAGTgcgag AACUAGCU m7b Created HHFKP_128632_cluster-19561_10_7
hsa-miR-106b-3p ggaagctAGTGCGag CCGCACUG m6b Created HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-1226-3p ggaaGCTGGTGcgag UCACCAGC m7b Disrupted HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-4661-5p ggaAGCTAGTgcgag AACUAGCU m7b Created HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-106b-3p ggaagctAGTGCGag CCGCACUG m6b Created HHFKP_128632_cluster-19561_10_7
hsa-miR-1226-3p ggaaGCTGGTGcgag UCACCAGC m7b Disrupted HHFKP_128632_cluster-19561_10_7
hsa-miR-4661-5p ggaAGCTAGTgcgag AACUAGCU m7b Created HHFKP_128632_cluster-19561_10_7
hsa-miR-106b-3p ggaagctAGTGCGag CCGCACUG m6b Created HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-1226-3p ggaaGCTGGTGcgag UCACCAGC m7b Disrupted HHRBL_12787_BCBL1-2of3-SCL_5416
hsa-miR-4661-5p ggaAGCTAGTgcgag AACUAGCU m7b Created HHRBL_12787_BCBL1-2of3-SCL_5416

Mutation Mutation ID Sample Name Cancer Type
chr6:g.150882819C>T COSM1311668 TCGA-G2-A2EJ-01 [urinary_tract][bladder][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4509 tgcCCTTTAGatctc ACUAAAGG m7b Created HHFKP_128630_cluster-19561_8_65
hsa-miR-6864-5p tgCCCTTCAgatctc UUGAAGGG m7b (m7b->m6b) HHFKP_128630_cluster-19561_8_65
Mutation Mutation ID Sample Name Cancer Type
chr6:g.150882785C>T COSM3859109 TCGA-CG-4437-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Mutation Mutation ID Sample Name Cancer Type
chr6:g.150880341A>C COSN9497318 AOCS-150-3-1 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr6:g.150877824G>C COSM1194161 H358 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-27a-5p tgAAGCCCaggtaat AGGGCUUA m6b Created HHFKP_128627_cluster-19561_5_26
hsa-miR-378g tgaAGCCCAGgtaat ACUGGGCU m7b Created HHFKP_128627_cluster-19561_5_26
hsa-miR-4638-5p tgaAGCCGAGgtaat ACUCGGCU m7b Disrupted HHFKP_128627_cluster-19561_5_26
hsa-miR-4777-3p tgaagccGAGGTAat AUACCUCA m6b Disrupted HHFKP_128627_cluster-19561_5_26
hsa-miR-619-3p tgaagcCCAGGTaat GACCUGGA m6b Created HHFKP_128627_cluster-19561_5_26
hsa-miR-6742-3p tgaagCCCAGGTaat ACCUGGGU m7a Created HHFKP_128627_cluster-19561_5_26
hsa-miR-7851-3p tgaagCCCAGGTAat UACCUGGG m8a Created HHFKP_128627_cluster-19561_5_26
hsa-miR-939-3p tgaaGCCCAGGtaat CCCUGGGC m7b Created HHFKP_128627_cluster-19561_5_26

Mutation Mutation ID Sample Name Cancer Type
chr6:g.150877824G>A COSM1074538 TCGA-BS-A0UV-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-212-5p tgaaGCCAAGGTaat ACCUUGGC m8a Created HHFKP_128627_cluster-19561_5_26
hsa-miR-3200-3p tgaagcCAAGGTaat CACCUUGC m6b Created HHFKP_128627_cluster-19561_5_26
hsa-miR-4638-5p tgaAGCCGAGgtaat ACUCGGCU m7b Disrupted HHFKP_128627_cluster-19561_5_26
hsa-miR-4724-3p tgaagccAAGGTAat GUACCUUC m6b Created HHFKP_128627_cluster-19561_5_26
hsa-miR-4777-3p tgaagccGAGGTAat AUACCUCA m6b Disrupted HHFKP_128627_cluster-19561_5_26
hsa-miR-6813-3p tgaagCCAAGGTaat AACCUUGG m7b Created HHFKP_128627_cluster-19561_5_26
hsa-miR-6815-3p tGAAGCCAaggtaat UGGCUUCU m7a Created HHFKP_128627_cluster-19561_5_26

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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