SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_002412
Gene Symbol: MGMT
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr10:g.129766799C>T COSM3435686 TCGA-D3-A2JF-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1255a ccatcCTCATCCcgt AGGAUGAG m7b Disrupted HHFCT_23521_cluster-2782_26_6
hsa-miR-1255b-5p ccatcCTCATCCcgt CGGAUGAG m7b Disrupted HHFCT_23521_cluster-2782_26_6
hsa-miR-3605-5p cCATCCTCAtcccgt UGAGGAUG m8a (m8a->m7a) HHFCT_23521_cluster-2782_26_6
hsa-miR-5187-5p ccatccTCATCCCgt UGGGAUGA m7b Disrupted HHFCT_23521_cluster-2782_26_6
hsa-miR-541-5p ccATCCTTatcccgt AAAGGAUU m6b Created HHFCT_23521_cluster-2782_26_6
hsa-miR-1185-5p ccATCCTCatcccgt AGAGGAUA m6b Disrupted HHFCT_23521_cluster-2782_26_6
hsa-miR-1255a ccatcCTCATCCcgt AGGAUGAG m7b Disrupted HHFCT_23521_cluster-2782_26_6
hsa-miR-1255b-5p ccatcCTCATCCcgt CGGAUGAG m7b Disrupted HHFCT_23521_cluster-2782_26_6
hsa-miR-3605-5p cCATCCTCAtcccgt UGAGGAUG m8a (m8a->m7a) HHFCT_23521_cluster-2782_26_6
hsa-miR-5187-5p ccatccTCATCCCgt UGGGAUGA m7b Disrupted HHFCT_23521_cluster-2782_26_6
hsa-miR-541-5p ccATCCTTatcccgt AAAGGAUU m6b Created HHFCT_23521_cluster-2782_26_6

Mutation Mutation ID Sample Name Cancer Type
chr10:g.129759317G>T COSM1257687 ESO-0125 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1273g-3p gaGCAGTGGgaggag ACCACUGC m7b (m7b->m6b) HHFCT_23520_cluster-2782_25_10
hsa-miR-2116-3p gagcagTGGGAGGag CCUCCCAU m7a Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-3156-3p gagcAGTGGGAGgag CUCCCACU m8a Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-4691-5p gagcagtTGGAGGAg GUCCUCCA m7b Created HHFCT_23520_cluster-2782_25_10
hsa-miR-519d-5p gagcagTTGGAGGag CCUCCAAA m7a Created HHFCT_23520_cluster-2782_25_10
hsa-miR-532-3p gagcaGTGGGAGGag CCUCCCAC m8a Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-6749-3p gagcagtGGGAGGAg CUCCUCCC m7b Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-6792-3p gagcagtTGGAGGAg CUCCUCCA m7b Created HHFCT_23520_cluster-2782_25_10
hsa-miR-1273g-3p gaGCAGTGGgaggag ACCACUGC m7b (m7b->m6b) HHFKP_22315_cluster-2782_16_8
hsa-miR-2116-3p gagcagTGGGAGGag CCUCCCAU m7a Disrupted HHFKP_22315_cluster-2782_16_8
hsa-miR-3156-3p gagcAGTGGGAGgag CUCCCACU m8a Disrupted HHFKP_22315_cluster-2782_16_8
hsa-miR-4691-5p gagcagtTGGAGGAg GUCCUCCA m7b Created HHFKP_22315_cluster-2782_16_8
hsa-miR-519d-5p gagcagTTGGAGGag CCUCCAAA m7a Created HHFKP_22315_cluster-2782_16_8
hsa-miR-532-3p gagcaGTGGGAGGag CCUCCCAC m8a Disrupted HHFKP_22315_cluster-2782_16_8
hsa-miR-6749-3p gagcagtGGGAGGAg CUCCUCCC m7b Disrupted HHFKP_22315_cluster-2782_16_8
hsa-miR-6792-3p gagcagtTGGAGGAg CUCCUCCA m7b Created HHFKP_22315_cluster-2782_16_8

Mutation Mutation ID Sample Name Cancer Type
chr10:g.129759309C>T COSM1215050 587224 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1178-3p agccgcGTGAGCAgt UUGCUCAC m7b Created HHFCT_23520_cluster-2782_25_10
hsa-miR-3186-3p agCCGCGTGAgcagt UCACGCGG m8a Created HHFCT_23520_cluster-2782_25_10
hsa-miR-4479 aGCCGCGCGagcagt CGCGCGGC m8a (m8a->m7a) HHFCT_23520_cluster-2782_25_10
hsa-miR-767-3p agccgcgTGAGCAGt UCUGCUCA m7b Created HHFCT_23520_cluster-2782_25_10
hsa-miR-1178-3p agccgcGTGAGCAgt UUGCUCAC m7b Created HHFKP_22315_cluster-2782_16_8
hsa-miR-3186-3p agCCGCGTGAgcagt UCACGCGG m8a Created HHFKP_22315_cluster-2782_16_8
hsa-miR-4479 aGCCGCGCGagcagt CGCGCGGC m8a (m8a->m7a) HHFKP_22315_cluster-2782_16_8
hsa-miR-767-3p agccgcgTGAGCAGt UCUGCUCA m7b Created HHFKP_22315_cluster-2782_16_8

Mutation Mutation ID Sample Name Cancer Type
chr10:g.129759309C>A COSM4144479 PTC-28C [thyroid][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4479 aGCCGCGCGagcagt CGCGCGGC m8a (m8a->m7a) HHFCT_23520_cluster-2782_25_10
hsa-miR-4479 aGCCGCGCGagcagt CGCGCGGC m8a (m8a->m7a) HHFKP_22315_cluster-2782_16_8
hsa-miR-4479 aGCCGCGCGagcagt CGCGCGGC m8a (m8a->m7a) HHFCT_23520_cluster-2782_25_10
hsa-miR-4479 aGCCGCGCGagcagt CGCGCGGC m8a (m8a->m7a) HHFKP_22315_cluster-2782_16_8

Mutation Mutation ID Sample Name Cancer Type
chr10:g.129759307C>T COSM1584868 TCGA-B5-A11E-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3177-3p aaaGCCGTGCgagca UGCACGGC m7b Created HHFCT_23520_cluster-2782_25_10
hsa-miR-4479 aaaGCCGCGCGagca CGCGCGGC m8a Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-3177-3p aaaGCCGTGCgagca UGCACGGC m7b Created HHFKP_22315_cluster-2782_16_8
hsa-miR-4479 aaaGCCGCGCGagca CGCGCGGC m8a Disrupted HHFKP_22315_cluster-2782_16_8
hsa-miR-3177-3p aaaGCCGTGCgagca UGCACGGC m7b Created HHFCT_23520_cluster-2782_25_10
hsa-miR-4479 aaaGCCGCGCGagca CGCGCGGC m8a Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-3177-3p aaaGCCGTGCgagca UGCACGGC m7b Created HHFKP_22315_cluster-2782_16_8
hsa-miR-4479 aaaGCCGCGCGagca CGCGCGGC m8a Disrupted HHFKP_22315_cluster-2782_16_8

Mutation Mutation ID Sample Name Cancer Type
chr10:g.129759298C>T COSM1675664 LOXIMVI [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][hairy_cell_leukaemia]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-193b-5p ggcAACCCCaaagcc CGGGGUUU m6b Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-3170 ggcAACCCCAaagcc CUGGGGUU m7b Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-377-5p ggCAACCTCaaagcc AGAGGUUG m7b (m6b->m7b) HHFCT_23520_cluster-2782_25_10
hsa-miR-4260 ggcaaCCCCAAagcc CUUGGGGC m6b Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-450a-2-3p ggcaaCCCCAAagcc AUUGGGGA m6b Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-5572 ggcaACCCCAAagcc GUUGGGGU m7b Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-6086 ggCAACCTCaaagcc GGAGGUUG m7b (m6b->m7b) HHFCT_23520_cluster-2782_25_10
hsa-miR-655-5p ggcAACCTCaaagcc AGAGGUUA m6b Created HHFCT_23520_cluster-2782_25_10
hsa-miR-656-5p GGCAACCTcaaagcc AGGUUGCC m8a Created HHFCT_23520_cluster-2782_25_10
hsa-miR-6737-5p ggcaACCCCAAagcc UUGGGGUG m7a Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-6812-5p ggcaACCCCAaagcc AUGGGGUG m6b Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-6819-5p ggcaACCCCAAagcc UUGGGGUG m7a Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-6855-5p ggcAACCCCAAagcc UUGGGGUU m8a Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-193b-5p ggcAACCCCaaagcc CGGGGUUU m6b Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-3170 ggcAACCCCAaagcc CUGGGGUU m7b Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-377-5p ggCAACCTCaaagcc AGAGGUUG m7b (m6b->m7b) HHFCT_23520_cluster-2782_25_10
hsa-miR-4260 ggcaaCCCCAAagcc CUUGGGGC m6b Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-450a-2-3p ggcaaCCCCAAagcc AUUGGGGA m6b Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-5572 ggcaACCCCAAagcc GUUGGGGU m7b Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-6086 ggCAACCTCaaagcc GGAGGUUG m7b (m6b->m7b) HHFCT_23520_cluster-2782_25_10
hsa-miR-655-5p ggcAACCTCaaagcc AGAGGUUA m6b Created HHFCT_23520_cluster-2782_25_10
hsa-miR-656-5p GGCAACCTcaaagcc AGGUUGCC m8a Created HHFCT_23520_cluster-2782_25_10
hsa-miR-6737-5p ggcaACCCCAAagcc UUGGGGUG m7a Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-6812-5p ggcaACCCCAaagcc AUGGGGUG m6b Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-6819-5p ggcaACCCCAAagcc UUGGGGUG m7a Disrupted HHFCT_23520_cluster-2782_25_10
hsa-miR-6855-5p ggcAACCCCAAagcc UUGGGGUU m8a Disrupted HHFCT_23520_cluster-2782_25_10

Mutation Mutation ID Sample Name Cancer Type
chr10:g.129759277T>C COSM4012679 TCGA-BR-8680-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-302f cAGCAATTAgcagcc UAAUUGCU m8a (m8a->m7a) HHFCT_23520_cluster-2782_25_10
hsa-miR-93-3p cagcaaTCAGCAGcc ACUGCUGA m7b Created HHFCT_23520_cluster-2782_25_10
hsa-miR-302f cAGCAATTAgcagcc UAAUUGCU m8a (m8a->m7a) HHFCT_23520_cluster-2782_25_10
hsa-miR-93-3p cagcaaTCAGCAGcc ACUGCUGA m7b Created HHFCT_23520_cluster-2782_25_10

Mutation Mutation ID Sample Name Cancer Type
chr10:g.129759245G>A COSM96024 107052 [breast][NS][carcinoma][HER-positive_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-5003-5p agGTTGTGAaattcg UCACAACA m7a (m7a->m6a) HHFKP_22314_cluster-2782_15_8
hsa-miR-513b-5p aggTTGTGAAattcg UUCACAAG m7a Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-590-3p aggttgTAAAATTcg UAAUUUUA m7b Created HHFKP_22314_cluster-2782_15_8

Mutation Mutation ID Sample Name Cancer Type
chr10:g.129759241T>C COSM358466 LUAD-CHTN-MAD06-00668 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-27a-3p ctgaaggCTGTGAAa UUCACAGU m7a Created HHFKP_22314_cluster-2782_15_8
hsa-miR-27b-3p ctgaaggCTGTGAAa UUCACAGU m7a Created HHFKP_22314_cluster-2782_15_8
hsa-miR-3614-3p ctGAAGGCTgtgaaa UAGCCUUC m7b (m6b->m7b) HHFKP_22314_cluster-2782_15_8
hsa-miR-5003-5p ctgaagGTTGTGAaa UCACAACA m7a Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-513a-5p ctgaaggCTGTGAAa UUCACAGG m7a Created HHFKP_22314_cluster-2782_15_8
hsa-miR-513b-5p ctgaaggTTGTGAAa UUCACAAG m7a Disrupted HHFKP_22314_cluster-2782_15_8

Mutation Mutation ID Sample Name Cancer Type
chr10:g.129759221G>T COSM4702046 T3094 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-21-3p gacaGGTGTTatgga CAACACCA m6b Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-3591-3p gacaGGTGTTatgga AAACACCA m6b Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-548aa gacaGGTTTTatgga AAAAACCA m6b Created HHFKP_22314_cluster-2782_15_8
hsa-miR-548ap-3p gacaGGTTTTatgga AAAAACCA m6b Created HHFKP_22314_cluster-2782_15_8
hsa-miR-548at-3p gacaGGTTTTatgga CAAAACCG m6b Created HHFKP_22314_cluster-2782_15_8
hsa-miR-548ay-3p gacaGGTTTTatgga CAAAACCG m6b Created HHFKP_22314_cluster-2782_15_8
hsa-miR-548t-3p gacaGGTTTTatgga AAAAACCA m6b Created HHFKP_22314_cluster-2782_15_8
hsa-miR-649 gACAGGTTTtatgga AAACCUGU m8a (m7a->m8a) HHFKP_22314_cluster-2782_15_8
hsa-miR-21-3p gacaGGTGTTatgga CAACACCA m6b Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-3591-3p gacaGGTGTTatgga AAACACCA m6b Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-548aa gacaGGTTTTatgga AAAAACCA m6b Created HHFKP_22314_cluster-2782_15_8
hsa-miR-548ap-3p gacaGGTTTTatgga AAAAACCA m6b Created HHFKP_22314_cluster-2782_15_8
hsa-miR-548at-3p gacaGGTTTTatgga CAAAACCG m6b Created HHFKP_22314_cluster-2782_15_8
hsa-miR-548ay-3p gacaGGTTTTatgga CAAAACCG m6b Created HHFKP_22314_cluster-2782_15_8
hsa-miR-548t-3p gacaGGTTTTatgga AAAAACCA m6b Created HHFKP_22314_cluster-2782_15_8
hsa-miR-649 gACAGGTTTtatgga AAACCUGU m8a (m7a->m8a) HHFKP_22314_cluster-2782_15_8

Mutation Mutation ID Sample Name Cancer Type
chr10:g.129759214G>A COSM427248 TCGA-BH-A0HK-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1231 ttcaCCAGACAggtg GUGUCUGG m7b Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-3120-5p ttcacCAGACAGGtg CCUGUCUG m8a Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-4299 tTCACCAGacaggtg GCUGGUGA m7b Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-4421 ttcaccAGACAGGTg ACCUGUCU m8a Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-4456 ttCACCAGacaggtg CCUGGUGG m6b Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-548q ttCACCAGacaggtg GCUGGUGC m6b Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-5699-3p ttcaccAGACAGGtg UCCUGUCU m7b Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-6740-5p ttcaCCAAACaggtg AGUUUGGG m6b Created HHFKP_22314_cluster-2782_15_8
hsa-miR-7855-5p tTCACCAAacaggtg UUGGUGAG m7a Created HHFKP_22314_cluster-2782_15_8

Mutation Mutation ID Sample Name Cancer Type
chr10:g.129759212C>A COSM537962 TCGA-75-5122-01 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1231 cgttcaCCAGACAgg GUGUCUGG m7b Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-3120-5p cgttcacCAGACAGg CCUGUCUG m7b Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-4299 cgtTCACCAGacagg GCUGGUGA m7b Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-4456 cgttCACCAGacagg CCUGGUGG m6b Disrupted HHFKP_22314_cluster-2782_15_8
hsa-miR-548q cgttCACCAGacagg GCUGGUGC m6b Disrupted HHFKP_22314_cluster-2782_15_8

Mutation Mutation ID Sample Name Cancer Type
chr10:g.129719368G>A COSN15479024 AOCS-111-1-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3189-5p cgcTGGGGCAacctc UGCCCCAU m7a Disrupted HHFCT_23519_cluster-2782_24_7
hsa-miR-323b-5p cgctggGACAACCTc AGGUUGUC m8a Created HHFCT_23519_cluster-2782_24_7
hsa-miR-410-5p cgctggGACAACCTc AGGUUGUC m8a Created HHFCT_23519_cluster-2782_24_7
hsa-miR-4433a-5p cgcTGGGACaacctc CGUCCCAC m6b Created HHFCT_23519_cluster-2782_24_7
hsa-miR-4433b-5p cgcTGGGACAacctc AUGUCCCA m7b Created HHFCT_23519_cluster-2782_24_7
hsa-miR-4646-3p cgctGGGACAAcctc AUUGUCCC m7b Created HHFCT_23519_cluster-2782_24_7
hsa-miR-4758-3p cgcTGGGGCAacctc UGCCCCAC m7a Disrupted HHFCT_23519_cluster-2782_24_7
hsa-miR-494-5p cgctggGACAACCTc AGGUUGUC m8a Created HHFCT_23519_cluster-2782_24_7
hsa-miR-5699-5p cgcTGGGGCAacctc UGCCCCAA m7a Disrupted HHFCT_23519_cluster-2782_24_7
hsa-miR-656-5p cgctggGGCAACCTc AGGUUGCC m8a Disrupted HHFCT_23519_cluster-2782_24_7
hsa-miR-7977 cGCTGGGAcaacctc UUCCCAGC m7b Created HHFCT_23519_cluster-2782_24_7

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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