SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

Transcript ID:	hsa_circ_0086268
Gene Symbol:	JAK2
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Somatic mutations that impact miRNA target sites

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.5078317C>T		COSM753373	TCGA-33-4532-01	[lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-3659	aaAACACTCttattc	UGAGUGUU	m7b	(m6b->m7b)	HHHNE_9003_JAK2|NM_004972|exon_CDS|-5.12376796768488|-2.26224175044196
hsa-miR-609	aaAACACCCTtattc	AGGGUGUU	m8a	Disrupted	HHHNE_9003_JAK2|NM_004972|exon_CDS|-5.12376796768488|-2.26224175044196
hsa-miR-3659	aaAACACTCttattc	UGAGUGUU	m7b	(m6b->m7b)	HHHSE_9003_JAK2|NM_004972|exon_CDS|-5.12376796768488|-2.26224175044196
hsa-miR-609	aaAACACCCTtattc	AGGGUGUU	m8a	Disrupted	HHHSE_9003_JAK2|NM_004972|exon_CDS|-5.12376796768488|-2.26224175044196

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.5077560G>A		COSM3907525	TCGA-CD-A4MG-01	[stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-505-3p	acaGTTGACatgggc	CGUCAACA	m6b	Created	HHFKP_147882_cluster-22649_9_27
hsa-miR-6872-3p	acagttGGCATGGGc	CCCAUGCC	m8a	Disrupted	HHFKP_147882_cluster-22649_9_27

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.5077540T>G		COSM3907524	TCGA-BR-6706-01	[stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-4465	tggaaACTTGAagtt	CUCAAGUA	m6b	Disrupted	HHFKP_147882_cluster-22649_9_27

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.5077535G>A		COSM1700806	YUZINO	[skin][mucosal][malignant_melanoma][NS]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-335-3p	tattATGAAAActtg	UUUUUCAU	m7b	Created	HHFKP_147882_cluster-22649_9_27
hsa-miR-587	tatTATGGAAActtg	UUUCCAUA	m8a	Disrupted	HHFKP_147882_cluster-22649_9_27

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.5077528T>C		COSM3699704	TCGA-AM-5820-01	[large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-1277-5p	ataaATATATTatgg	AAAUAUAU	m7b	Disrupted	HHFKP_147882_cluster-22649_9_27
hsa-miR-5692b	ataaatATATTATgg	AAUAAUAU	m7b	Disrupted	HHFKP_147882_cluster-22649_9_27
hsa-miR-5692c	ataaatATATTATgg	AAUAAUAU	m7b	Disrupted	HHFKP_147882_cluster-22649_9_27

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.5077469G>T		COSM1462576	TCGA-AZ-6598-01	[large_intestine][caecum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-3653-5p	tTCAGGAGtttgtaa	CCUCCUGA	m7b	Disrupted	HHFKP_147881_cluster-22649_8_6
hsa-miR-4668-3p	ttcaGGATTTTgtaa	GAAAAUCC	m7b	Created	HHFKP_147881_cluster-22649_8_6
hsa-miR-8063	ttcagGATTTTGtaa	UCAAAAUC	m7b	Created	HHFKP_147881_cluster-22649_8_6

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.5077469G>A		COSM27638	1141822	[haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][myelodysplastic-myeloproliferative_neoplasm-unclassifiable]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.5077468A>G		COSM1569947	TCGA-DC-5869-01	[large_intestine][rectum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-345-3p	gTTCAGGGgtttgta	GCCCUGAA	m7b	Created	HHFKP_147881_cluster-22649_8_6
hsa-miR-3653-5p	gtTCAGGAGtttgta	CCUCCUGA	m7b	(m7b->m6b)	HHFKP_147881_cluster-22649_8_6
hsa-miR-6771-3p	gttcaGGGGTTTGta	CAAACCCC	m8a	Created	HHFKP_147881_cluster-22649_8_6

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.5077467G>A		COSM1462575	TCGA-CK-6746-01	[large_intestine][caecum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-3653-5p	ggtTCAGGAGtttgt	CCUCCUGA	m7b	Disrupted	HHFKP_147881_cluster-22649_8_6

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.5077459T>C		COSM29120	TCGA-AZ-6606-01	[large_intestine][caecum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.5077454T>C		COSM2777212	LS411	[large_intestine][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-4288	atGCAGACAttctgg	UUGUCUGC	m7b	(m6b->m7b)	HHFKP_147881_cluster-22649_8_6
hsa-miR-632	atGCAGACAttctgg	GUGUCUGC	m7b	(m6b->m7b)	HHFKP_147881_cluster-22649_8_6
hsa-miR-654-3p	atgCAGACATtctgg	UAUGUCUG	m7b	Created	HHFKP_147881_cluster-22649_8_6

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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