SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_001297757
Gene Symbol: HELQ
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr4:g.83455686A>C COSM4411457 RMH008-R6 [kidney][NS][carcinoma][clear_cell_renal_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-181a-5p atggaTGAATGTggt AACAUUCA m7b Disrupted HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-181b-5p atggaTGAATGTggt AACAUUCA m7b Disrupted HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-181c-5p atggaTGAATGTggt AACAUUCA m7b Disrupted HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-181d-5p atggaTGAATGTggt AACAUUCA m7b Disrupted HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-324-5p atGGATGCatgtggt CGCAUCCC m6b Created HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-4262 atggaTGAATGTggt GACAUUCA m7b Disrupted HHRBC_9663_BC3-2of3-SCL_5995

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83455673C>A COSM4882502 OSCC-GB_01060111 [upper_aerodigestive_tract][mouth][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-425-3p gTTCCCGAatccgcc AUCGGGAA m7b Created HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-6771-5p gtTCCCGAatccgcc CUCGGGAG m6b Created HHRBC_9663_BC3-2of3-SCL_5995

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83455671AT>T COSM3733662 2P3 [pancreas][NS][pancreatic_intraepithelial_neoplasia_(PanIN)][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-25-5p ttcccgCTCCGCCgg AGGCGGAG m7b Created HHRBC_9663_BC3-2of3-SCL_5995
Mutation Mutation ID Sample Name Cancer Type
chr4:g.83455669C>T COSM110494 18T [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr4:g.83455668G>C COSM3365724 TCGA-B0-4690-01 [kidney][NS][carcinoma][clear_cell_renal_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4525 cgcATCCCCCggcgg GGGGGGAU m7b Created HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-5010-5p cgcATCCCCCggcgg AGGGGGAU m7b Created HHRBC_9663_BC3-2of3-SCL_5995

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83455654C>G COSM1291976 CLL116 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1343-5p ggtgtctCTCCCCAa UGGGGAGC m7a Disrupted HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-185-5p ggtgTCTCTCCccaa UGGAGAGA m7b Disrupted HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-3144-5p ggtgtctGTCCCCaa AGGGGACC m6b Created HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-3150a-3p ggtgtctCTCCCCAa CUGGGGAG m7b Disrupted HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-3175 ggtgtcTCTCCCCaa CGGGGAGA m7b Disrupted HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-3191-3p ggtgtctGTCCCCAa UGGGGACG m7a Created HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-4306 ggtgTCTCTCCccaa UGGAGAGA m7b Disrupted HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-4644 ggtgTCTCTCCccaa UGGAGAGA m7b Disrupted HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-4652-5p ggtgtctGTCCCCaa AGGGGACU m6b Created HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-6731-5p ggtgtCTCTCCCcaa UGGGAGAG m7b Disrupted HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-6763-5p ggtgtctCTCCCCAa CUGGGGAG m7b Disrupted HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-6810-5p ggtgtctGTCCCCAa AUGGGGAC m7b Created HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-6825-5p ggtgtctCTCCCCAa UGGGGAGG m7a Disrupted HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-8085 ggtgtCTCTCCCcaa UGGGAGAG m7b Disrupted HHRBC_9663_BC3-2of3-SCL_5995
hsa-miR-939-5p ggtgtctCTCCCCAa UGGGGAGC m7a Disrupted HHRBC_9663_BC3-2of3-SCL_5995

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83453896A>G COSM3606616 TCGA-FS-A1ZT-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-145-5p tttACTGGAaactcc GUCCAGUU m6b Created HHFKP_107120_cluster-17682_3_270
hsa-miR-222-5p ttTACTGAaaactcc CUCAGUAG m6b Disrupted HHFKP_107120_cluster-17682_3_270
hsa-miR-30a-3p tttACTGAAAactcc CUUUCAGU m7b Disrupted HHFKP_107120_cluster-17682_3_270
hsa-miR-30d-3p tttACTGAAAactcc CUUUCAGU m7b Disrupted HHFKP_107120_cluster-17682_3_270
hsa-miR-30e-3p tttACTGAAAactcc CUUUCAGU m7b Disrupted HHFKP_107120_cluster-17682_3_270
hsa-miR-3180-5p tttaCTGGAAactcc CUUCCAGA m6b Created HHFKP_107120_cluster-17682_3_270
hsa-miR-4712-5p ttTACTGGAaactcc UCCAGUAC m7a (m6a->m7a) HHFKP_107120_cluster-17682_3_270
hsa-miR-5195-3p tttACTGGAaactcc AUCCAGUU m6b Created HHFKP_107120_cluster-17682_3_270
hsa-miR-545-5p TTTACTGAaaactcc UCAGUAAA m8a Disrupted HHFKP_107120_cluster-17682_3_270
hsa-miR-770-5p ttTACTGGAaactcc UCCAGUAC m7a (m6a->m7a) HHFKP_107120_cluster-17682_3_270
hsa-miR-145-5p tttACTGGAaactcc GUCCAGUU m6b Created HPSEF_17237_G20788.1_84375042
hsa-miR-222-5p ttTACTGAaaactcc CUCAGUAG m6b Disrupted HPSEF_17237_G20788.1_84375042
hsa-miR-30a-3p tttACTGAAAactcc CUUUCAGU m7b Disrupted HPSEF_17237_G20788.1_84375042
hsa-miR-30d-3p tttACTGAAAactcc CUUUCAGU m7b Disrupted HPSEF_17237_G20788.1_84375042
hsa-miR-30e-3p tttACTGAAAactcc CUUUCAGU m7b Disrupted HPSEF_17237_G20788.1_84375042
hsa-miR-3180-5p tttaCTGGAAactcc CUUCCAGA m6b Created HPSEF_17237_G20788.1_84375042
hsa-miR-4712-5p ttTACTGGAaactcc UCCAGUAC m7a (m6a->m7a) HPSEF_17237_G20788.1_84375042
hsa-miR-5195-3p tttACTGGAaactcc AUCCAGUU m6b Created HPSEF_17237_G20788.1_84375042
hsa-miR-545-5p TTTACTGAaaactcc UCAGUAAA m8a Disrupted HPSEF_17237_G20788.1_84375042
hsa-miR-770-5p ttTACTGGAaactcc UCCAGUAC m7a (m6a->m7a) HPSEF_17237_G20788.1_84375042

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83453885A>G COSM3826344 TCGA-AO-A128-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1283 ctccTTTGTAGctca UCUACAAA m7b Created HPKTA_46818_G50537.1_84375036
hsa-miR-142-5p ctcCTTTATagctca CAUAAAGU m6b Disrupted HPKTA_46818_G50537.1_84375036
hsa-miR-187-5p ctcctTTGTAGCtca GGCUACAA m7b Created HPKTA_46818_G50537.1_84375036
hsa-miR-340-5p ctcCTTTATAgctca UUAUAAAG m7b Disrupted HPKTA_46818_G50537.1_84375036
hsa-miR-520d-5p ctcCTTTGTAGctca CUACAAAG m8a Created HPKTA_46818_G50537.1_84375036
hsa-miR-524-5p ctcCTTTGTAGctca CUACAAAG m8a Created HPKTA_46818_G50537.1_84375036
hsa-miR-5590-3p ctcCTTTATagctca AAUAAAGU m6b Disrupted HPKTA_46818_G50537.1_84375036
hsa-miR-1283 ctccTTTGTAGctca UCUACAAA m7b Created HPSEF_17237_G20788.1_84375042
hsa-miR-142-5p ctcCTTTATagctca CAUAAAGU m6b Disrupted HPSEF_17237_G20788.1_84375042
hsa-miR-187-5p ctcctTTGTAGCtca GGCUACAA m7b Created HPSEF_17237_G20788.1_84375042
hsa-miR-340-5p ctcCTTTATAgctca UUAUAAAG m7b Disrupted HPSEF_17237_G20788.1_84375042
hsa-miR-520d-5p ctcCTTTGTAGctca CUACAAAG m8a Created HPSEF_17237_G20788.1_84375042
hsa-miR-524-5p ctcCTTTGTAGctca CUACAAAG m8a Created HPSEF_17237_G20788.1_84375042
hsa-miR-5590-3p ctcCTTTATagctca AAUAAAGU m6b Disrupted HPSEF_17237_G20788.1_84375042

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83453793G>A COSM734444 TCGA-18-3409-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1199-5p tttGCTCAGaaagta CCUGAGCC m6b Created HPRO6_58674_G70134.1_84374950
hsa-miR-3124-3p tttgctcGGAAAGTa ACUUUCCU m7a Disrupted HPRO6_58674_G70134.1_84374950
hsa-miR-4303 tttGCTCAGAAagta UUCUGAGC m8a Created HPRO6_58674_G70134.1_84374950
hsa-miR-4762-3p tttgcTCAGAAagta CUUCUGAU m6b Created HPRO6_58674_G70134.1_84374950
hsa-miR-615-3p tttGCTCGGAaagta UCCGAGCC m7a Disrupted HPRO6_58674_G70134.1_84374950
hsa-miR-6751-3p tttGCTCAGaaagta ACUGAGCC m6b Created HPRO6_58674_G70134.1_84374950
hsa-miR-1199-5p tttGCTCAGaaagta CCUGAGCC m6b Created HPTK1_22382_G26765.1_84374950
hsa-miR-3124-3p tttgctcGGAAAGTa ACUUUCCU m7a Disrupted HPTK1_22382_G26765.1_84374950
hsa-miR-4303 tttGCTCAGAAagta UUCUGAGC m8a Created HPTK1_22382_G26765.1_84374950
hsa-miR-4762-3p tttgcTCAGAAagta CUUCUGAU m6b Created HPTK1_22382_G26765.1_84374950
hsa-miR-615-3p tttGCTCGGAaagta UCCGAGCC m7a Disrupted HPTK1_22382_G26765.1_84374950
hsa-miR-6751-3p tttGCTCAGaaagta ACUGAGCC m6b Created HPTK1_22382_G26765.1_84374950
hsa-miR-1199-5p tttGCTCAGaaagta CCUGAGCC m6b Created HPTK7_5712_G8558.1_84374950
hsa-miR-3124-3p tttgctcGGAAAGTa ACUUUCCU m7a Disrupted HPTK7_5712_G8558.1_84374950
hsa-miR-4303 tttGCTCAGAAagta UUCUGAGC m8a Created HPTK7_5712_G8558.1_84374950
hsa-miR-4762-3p tttgcTCAGAAagta CUUCUGAU m6b Created HPTK7_5712_G8558.1_84374950
hsa-miR-615-3p tttGCTCGGAaagta UCCGAGCC m7a Disrupted HPTK7_5712_G8558.1_84374950
hsa-miR-6751-3p tttGCTCAGaaagta ACUGAGCC m6b Created HPTK7_5712_G8558.1_84374950

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83453792G>A COSM734446 TCGA-18-3409-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3124-3p ttgctcGGAAAGTat ACUUUCCU m7a Disrupted HPRO6_58674_G70134.1_84374950
hsa-miR-5003-3p ttgctcGAAAAGTAt UACUUUUC m8a Created HPRO6_58674_G70134.1_84374950
hsa-miR-615-3p ttGCTCGGAaagtat UCCGAGCC m7a (m7a->m6a) HPRO6_58674_G70134.1_84374950
hsa-miR-3124-3p ttgctcGGAAAGTat ACUUUCCU m7a Disrupted HPTK1_22382_G26765.1_84374950
hsa-miR-5003-3p ttgctcGAAAAGTAt UACUUUUC m8a Created HPTK1_22382_G26765.1_84374950
hsa-miR-615-3p ttGCTCGGAaagtat UCCGAGCC m7a (m7a->m6a) HPTK1_22382_G26765.1_84374950
hsa-miR-3124-3p ttgctcGGAAAGTat ACUUUCCU m7a Disrupted HPTK7_5712_G8558.1_84374950
hsa-miR-5003-3p ttgctcGAAAAGTAt UACUUUUC m8a Created HPTK7_5712_G8558.1_84374950
hsa-miR-615-3p ttGCTCGGAaagtat UCCGAGCC m7a (m7a->m6a) HPTK7_5712_G8558.1_84374950

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83453772C>G COSM734447 TCGA-60-2698-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4663 acaaaCTCAGCatta AGCUGAGC m6b Disrupted HPCB1_30500_G38991.1_84374929
hsa-miR-4682 acaAACTCAGcatta UCUGAGUU m7b Disrupted HPCB1_30500_G38991.1_84374929
hsa-miR-4728-3p acaaacTCAGCATta CAUGCUGA m7b Disrupted HPCB1_30500_G38991.1_84374929
hsa-miR-8077 acaaACTCAGCatta GGCUGAGU m7b Disrupted HPCB1_30500_G38991.1_84374929
hsa-miR-4328 acAAACTGagcatta CCAGUUUU m6b Created HPCB3_17506_G24035.1_84374929
hsa-miR-4663 acaaaCTCAGCatta AGCUGAGC m6b Disrupted HPCB3_17506_G24035.1_84374929
hsa-miR-4682 acaAACTCAGcatta UCUGAGUU m7b Disrupted HPCB3_17506_G24035.1_84374929
hsa-miR-4728-3p acaaacTCAGCATta CAUGCUGA m7b Disrupted HPCB3_17506_G24035.1_84374929
hsa-miR-8077 acaaACTCAGCatta GGCUGAGU m7b Disrupted HPCB3_17506_G24035.1_84374929
hsa-miR-4328 acAAACTGagcatta CCAGUUUU m6b Created HPSEF_17236_G20787.1_84374929
hsa-miR-4663 acaaaCTCAGCatta AGCUGAGC m6b Disrupted HPSEF_17236_G20787.1_84374929
hsa-miR-4682 acaAACTCAGcatta UCUGAGUU m7b Disrupted HPSEF_17236_G20787.1_84374929
hsa-miR-4728-3p acaaacTCAGCATta CAUGCUGA m7b Disrupted HPSEF_17236_G20787.1_84374929
hsa-miR-8077 acaaACTCAGCatta GGCUGAGU m7b Disrupted HPSEF_17236_G20787.1_84374929

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83453299C>T COSM4513605 CSCC-19-T [skin][head_neck][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-6816-3p cttGGTCCTTtttat GAAGGACC m7b Disrupted HPCB1_30499_G38990.1_84374434

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83453298T>G COSM481617 TCGA-A3-3357-01 [kidney][NS][carcinoma][clear_cell_renal_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-424-3p ttggtcCGTTTTatt CAAAACGU m6b Created HPCB1_30499_G38990.1_84374434
hsa-miR-548ad-3p ttggtcCGTTTTatt GAAAACGA m6b Created HPCB1_30499_G38990.1_84374434
hsa-miR-553 ttggtCCGTTTTatt AAAACGGU m7a Created HPCB1_30499_G38990.1_84374434
hsa-miR-6816-3p ttGGTCCTTtttatt GAAGGACC m7b (m7b->m6b) HPCB1_30499_G38990.1_84374434

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83407510A>G COSM370127 LUAD-NYU1219 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-374b-3p aagagtTGCTAAGat CUUAGCAG m7a Created HHFCT_115247_cluster-17682_1_8
hsa-miR-4766-3p aagagTTGCTAagat AUAGCAAU m6b Created HHFCT_115247_cluster-17682_1_8
hsa-miR-802 aagaGTTACTaagat CAGUAACA m6b Disrupted HHFCT_115247_cluster-17682_1_8

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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