SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_005228
Gene Symbol: EGFR
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr7:g.55206898G>A COSN6886895 RK019_C [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3692-3p tagTGTGGAAttcag GUUCCACA m7b Disrupted HHFKP_134905_cluster-20793_82_41
hsa-miR-377-3p taGTGTGAaattcag AUCACACA m6b Created HHFKP_134905_cluster-20793_82_41
hsa-miR-4452 tagtgtgGAATTCAg UUGAAUUC m7b Disrupted HHFKP_134905_cluster-20793_82_41
hsa-miR-3692-3p tagTGTGGAAttcag GUUCCACA m7b Disrupted HHFKP_134905_cluster-20793_82_41
hsa-miR-377-3p taGTGTGAaattcag AUCACACA m6b Created HHFKP_134905_cluster-20793_82_41
hsa-miR-4452 tagtgtgGAATTCAg UUGAAUUC m7b Disrupted HHFKP_134905_cluster-20793_82_41

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55206679G>A COSN8029070 8031146 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-374c-5p agttTGTATTActta AUAAUACA m7b Created HHFCT_146505_cluster-20793_66_39
hsa-miR-655-3p agttTGTATTActta AUAAUACA m7b Created HHFCT_146505_cluster-20793_66_39
hsa-miR-802 agtttgTGTTACTta CAGUAACA m7b Disrupted HHFCT_146505_cluster-20793_66_39

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55206531G>A COSN9994283 AOCS-108-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1250-5p tAGCACCGcttttgt ACGGUGCU m7b Disrupted HHFKP_134901_cluster-20793_78_430
hsa-miR-4746-3p taGCACCGCTtttgt AGCGGUGC m8a Disrupted HHFKP_134901_cluster-20793_78_430
hsa-miR-4796-3p tagcaCCACTTTtgt UAAAGUGG m7b Created HHFKP_134901_cluster-20793_78_430
hsa-miR-548az-5p tagcacCACTTTTGt CAAAAGUG m8a Created HHFKP_134901_cluster-20793_78_430
hsa-miR-548t-5p tagcacCACTTTTGt CAAAAGUG m8a Created HHFKP_134901_cluster-20793_78_430

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55206521G>C COSN8029069 8067180 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-362-5p tacctAAGGATagca AAUCCUUG m6b Disrupted HHFKP_134901_cluster-20793_78_430
hsa-miR-500b-5p tacctAAGGATagca AAUCCUUG m6b Disrupted HHFKP_134901_cluster-20793_78_430
hsa-miR-501-5p tacctAAGGATagca AAUCCUUU m6b Disrupted HHFKP_134901_cluster-20793_78_430

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55206294C>T COSN229663
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-132-5p gtccCCACGGTactt ACCGUGGC m7a Disrupted HHFCT_146502_cluster-20793_61_40
hsa-miR-491-5p gTCCCCACggtactt AGUGGGGA m7b Disrupted HHFCT_146502_cluster-20793_61_40
hsa-miR-624-5p gtccccaTGGTACTt UAGUACCA m7b Created HHFCT_146502_cluster-20793_61_40
hsa-miR-7153-3p gtccCCATGGTactt CACCAUGG m7b Created HHFCT_146502_cluster-20793_61_40
hsa-miR-132-5p gtccCCACGGTactt ACCGUGGC m7a Disrupted HHFKP_134900_cluster-20793_77_768
hsa-miR-491-5p gTCCCCACggtactt AGUGGGGA m7b Disrupted HHFKP_134900_cluster-20793_77_768
hsa-miR-624-5p gtccccaTGGTACTt UAGUACCA m7b Created HHFKP_134900_cluster-20793_77_768
hsa-miR-7153-3p gtccCCATGGTactt CACCAUGG m7b Created HHFKP_134900_cluster-20793_77_768

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55205594A>C COSM4680403 T3064 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1251-3p gccaCAAAGCagtga CGCUUUGC m6b Disrupted HHFCT_146496_cluster-20793_52_27

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55205587G>A COSM82120 PCSI_0466_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4466 gggtCGCACCacaaa GGGUGCGG m6b Created HHFKP_134895_cluster-20793_72_16
hsa-miR-7108-5p gggtcgcGCCACAaa GUGUGGCC m6b Disrupted HHFCT_146496_cluster-20793_52_27
hsa-miR-4634 gggTCGCGCCacaaa CGGCGCGA m7b Disrupted HHFCT_146496_cluster-20793_52_27
hsa-miR-4474-3p gggtcgcGCCACAAa UUGUGGCU m7a Disrupted HHFKP_134895_cluster-20793_72_16
hsa-miR-4634 gggTCGCGCCacaaa CGGCGCGA m7b Disrupted HHFKP_134895_cluster-20793_72_16
hsa-miR-7108-5p gggtcgcGCCACAaa GUGUGGCC m6b Disrupted HHFKP_134895_cluster-20793_72_16
hsa-miR-4474-3p gggtcgcGCCACAAa UUGUGGCU m7a Disrupted HHFCT_146496_cluster-20793_52_27
hsa-miR-4466 gggtCGCACCacaaa GGGUGCGG m6b Created HHFCT_146496_cluster-20793_52_27

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55205517C>T COSM3639760 TCGA-EB-A44P-01 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-539-5p ttcTTTCTCaaggaa GGAGAAAU m6b Created HHFKP_134894_cluster-20793_71_113
hsa-miR-6733-5p ttCTTTCCCAaggaa UGGGAAAG m8a Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-6739-5p ttCTTTCCCAaggaa UGGGAAAG m8a Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-212-5p ttctttcCCAAGGaa ACCUUGGC m6b Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-3153 ttCTTTCCCaaggaa GGGGAAAG m7b (m7b->m6b) HHFKP_134894_cluster-20793_71_113
hsa-miR-3189-3p ttctttCCCAAGGaa CCCUUGGG m7b Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-450a-1-3p ttctTTCCCAAggaa AUUGGGAA m7b Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-4668-5p ttcTTTCCCaaggaa AGGGAAAA m6b Disrupted HHFKP_134894_cluster-20793_71_113

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55205492C>T COSM1732319 LIS03PT2 [soft_tissue][fat][liposarcoma][myxoid-round_cell]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-296-3p ggaCAACCCTgacta GAGGGUUG m7b Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-323b-5p gGACAACCctgacta AGGUUGUC m7b Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-494-5p gGACAACCctgacta AGGUUGUC m7b Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-6823-5p ggacAACCCTGActa UCAGGGUU m8a Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-759 ggacaACTCTGacta GCAGAGUG m6b Created HHFKP_134894_cluster-20793_71_113

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55205486G>A COSM145359 082-02-1TD [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-198 tagcCTGGACaaccc GGUCCAGA m6b Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-323b-5p tagcctgGACAACCc AGGUUGUC m7b Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-3912-5p tagccTGGACAaccc AUGUCCAU m6b Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-410-5p tagcctgGACAACCc AGGUUGUC m7b Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-4645-5p taGCCTGGacaaccc ACCAGGCA m6b Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-494-5p tagcctgGACAACCc AGGUUGUC m7b Disrupted HHFKP_134894_cluster-20793_71_113

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55205483C>A COSM1090895 TCGA-AP-A059-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-198 aattagcCTGGACaa GGUCCAGA m6b Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-3155a aattAGCCTGGacaa CCAGGCUC m7a Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-3155b aattAGCCTGGacaa CCAGGCUC m7a Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-3912-5p aattagcATGGACAa AUGUCCAU m7b Created HHFKP_134894_cluster-20793_71_113
hsa-miR-4645-5p aattaGCCTGGacaa ACCAGGCA m6b Disrupted HHFKP_134894_cluster-20793_71_113
hsa-miR-5581-3p aattaGCATGGAcaa UUCCAUGC m7b Created HHFKP_134894_cluster-20793_71_113
hsa-miR-6872-3p aattaGCATGGacaa CCCAUGCC m6b Created HHFKP_134894_cluster-20793_71_113

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55205432A>T COSM4934357 TCGA-DD-A1EK-01 [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3160-3p caaCAGCTCattcga AGAGCUGA m6b Created HHFKP_134893_cluster-20793_70_18
hsa-miR-4487 caaCAGCTCattcga AGAGCUGG m6b Created HHFKP_134893_cluster-20793_70_18
hsa-miR-556-5p caacAGCTCATtcga GAUGAGCU m7b Created HHFKP_134893_cluster-20793_70_18

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55205423G>A COSM4680402 T3527 [large_intestine][rectum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-514a-3p cacctGTGTCAAcag AUUGACAC m7b Disrupted HHFKP_134893_cluster-20793_70_18
hsa-miR-514b-3p cacctGTGTCAAcag AUUGACAC m7b Disrupted HHFKP_134893_cluster-20793_70_18
hsa-miR-642a-3p caccTGTGTCaacag AGACACAU m6b Disrupted HHFKP_134893_cluster-20793_70_18
hsa-miR-642b-3p caccTGTGTCaacag AGACACAU m6b Disrupted HHFKP_134893_cluster-20793_70_18
hsa-miR-6768-5p caCCTGTGTcaacag CACACAGG m7b (m7b->m6b) HHFKP_134893_cluster-20793_70_18

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55205338G>A COSM4680401 T368 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-2277-5p acCCCGCGCccagca AGCGCGGG m7b (m7b->m6b) HHFKP_134892_cluster-20793_69_314
hsa-miR-3178 acccCGCGCCCagca GGGGCGCG m7b Disrupted HHFKP_134892_cluster-20793_69_314
hsa-miR-4466 accCCGCACCCagca GGGUGCGG m8a Created HHFKP_134892_cluster-20793_69_314
hsa-miR-4486 accccgCGCCCAGCa GCUGGGCG m8a Disrupted HHFKP_134892_cluster-20793_69_314
hsa-miR-5589-5p accccgcACCCAGCa GGCUGGGU m7b Created HHFKP_134892_cluster-20793_69_314
hsa-miR-612 accccgcGCCCAGCa GCUGGGCA m7a Disrupted HHFKP_134892_cluster-20793_69_314
hsa-miR-6741-5p accccGCACCCAgca GUGGGUGC m7b Created HHFKP_134892_cluster-20793_69_314
hsa-miR-675-5p accCCGCACCcagca UGGUGCGG m7b Created HHFKP_134892_cluster-20793_69_314
hsa-miR-6776-5p accccgCACCCAGca UCUGGGUG m7b Created HHFKP_134892_cluster-20793_69_314

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55205336G>A COSM327142 CCRF-CEM [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][acute_lymphoblastic_leukaemia]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1268a gaacccCACGCCCag CGGGCGUG m7b Created HHFKP_134892_cluster-20793_69_314
hsa-miR-1268b gaacccCACGCCCag CGGGCGUG m7b Created HHFKP_134892_cluster-20793_69_314
hsa-miR-2277-5p gaacCCCGCGCccag AGCGCGGG m7b Disrupted HHFKP_134892_cluster-20793_69_314
hsa-miR-3170 gAACCCCAcgcccag CUGGGGUU m7b Created HHFKP_134892_cluster-20793_69_314
hsa-miR-3178 gaacccCGCGCCCag GGGGCGCG m7b Disrupted HHFKP_134892_cluster-20793_69_314
hsa-miR-6742-5p gaACCCCACgcccag AGUGGGGU m7b (m6b->m7b) HHFKP_134892_cluster-20793_69_314
hsa-miR-6853-5p gaacCCCACGCccag AGCGUGGG m7b Created HHFKP_134892_cluster-20793_69_314
hsa-miR-6855-5p gAACCCCAcgcccag UUGGGGUU m7b Created HHFKP_134892_cluster-20793_69_314

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55205309G>A COSM1292529 CLL107 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4524b-3p gaatCCTGTCTatca GAGACAGG m7b Disrupted HHFCT_146495_cluster-20793_51_238
hsa-miR-4524b-3p gaatCCTGTCTatca GAGACAGG m7b Disrupted HHFKP_134892_cluster-20793_69_314

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55205287C>T COSM1451621 TCGA-D5-6930-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-214-3p aaaggCCTGCTGgct ACAGCAGG m7b Created HHFCT_146495_cluster-20793_51_238
hsa-miR-3619-5p aaaggCCTGCTGgct UCAGCAGG m7b Created HHFCT_146495_cluster-20793_51_238
hsa-miR-4530 aaaggcCTGCTGGct CCCAGCAG m7b Created HHFCT_146495_cluster-20793_51_238
hsa-miR-4650-5p aaAGGCCTGctggct UCAGGCCU m7b (m6b->m7b) HHFCT_146495_cluster-20793_51_238
hsa-miR-4690-5p aaagGCCTGCTggct GAGCAGGC m7b Created HHFCT_146495_cluster-20793_51_238
hsa-miR-6749-5p aaAGGCCCGctggct UCGGGCCU m7b (m7b->m6b) HHFCT_146495_cluster-20793_51_238
hsa-miR-761 aaaggCCTGCTGgct GCAGCAGG m7b Created HHFCT_146495_cluster-20793_51_238
hsa-miR-1245b-5p aAAGGCCTgctggct UAGGCCUU m7b Created HHFKP_134892_cluster-20793_69_314
hsa-miR-214-3p aaaggCCTGCTGgct ACAGCAGG m7b Created HHFKP_134892_cluster-20793_69_314
hsa-miR-3619-5p aaaggCCTGCTGgct UCAGCAGG m7b Created HHFKP_134892_cluster-20793_69_314
hsa-miR-4530 aaaggcCTGCTGGct CCCAGCAG m7b Created HHFKP_134892_cluster-20793_69_314
hsa-miR-4650-5p aaAGGCCTGctggct UCAGGCCU m7b (m6b->m7b) HHFKP_134892_cluster-20793_69_314
hsa-miR-4690-5p aaagGCCTGCTggct GAGCAGGC m7b Created HHFKP_134892_cluster-20793_69_314
hsa-miR-6749-5p aaAGGCCCGctggct UCGGGCCU m7b (m7b->m6b) HHFKP_134892_cluster-20793_69_314
hsa-miR-761 aaaggCCTGCTGgct GCAGCAGG m7b Created HHFKP_134892_cluster-20793_69_314

Mutation Mutation ID Sample Name Cancer Type
chr7:g.55205284G>T COSM341496 LUAD-F00368 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-365a-5p ccaaAAGTCCCgctg AGGGACUU m7b Created HHFCT_146495_cluster-20793_51_238
hsa-miR-365b-5p ccaaAAGTCCCgctg AGGGACUU m7b Created HHFCT_146495_cluster-20793_51_238
hsa-miR-6749-5p ccaaaAGGCCCGctg UCGGGCCU m7b Disrupted HHFCT_146495_cluster-20793_51_238
hsa-miR-365a-5p ccaaAAGTCCCgctg AGGGACUU m7b Created HHFKP_134892_cluster-20793_69_314
hsa-miR-365b-5p ccaaAAGTCCCgctg AGGGACUU m7b Created HHFKP_134892_cluster-20793_69_314
hsa-miR-6749-5p ccaaaAGGCCCGctg UCGGGCCU m7b Disrupted HHFKP_134892_cluster-20793_69_314

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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