SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_000745
Gene Symbol: CHRNA5
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Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr15:g.78590593G>A COSM167539 TCGA-AG-A002-01 [large_intestine][rectum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1257 tctATTCACTacatt AGUGAAUG m7a Created HPRO6_27261_G32138.1_78882932
hsa-miR-3606-5p tctaTTCACTAcatt UUAGUGAA m7b Created HPRO6_27261_G32138.1_78882932
hsa-miR-5585-3p tCTATTCActacatt CUGAAUAG m7b Created HPRO6_27261_G32138.1_78882932
hsa-miR-6073 tctatTCACTACatt GGUAGUGA m7b Created HPRO6_27261_G32138.1_78882932
hsa-miR-7852-3p tctattcACTACATt UAUGUAGU m7b Created HPRO6_27261_G32138.1_78882932
hsa-miR-1257 tctATTCACTacatt AGUGAAUG m7a Created HPSLC_6875_G8130.1_78882933
hsa-miR-3606-5p tctaTTCACTAcatt UUAGUGAA m7b Created HPSLC_6875_G8130.1_78882933
hsa-miR-5585-3p tCTATTCActacatt CUGAAUAG m7b Created HPSLC_6875_G8130.1_78882933
hsa-miR-6073 tctatTCACTACatt GGUAGUGA m7b Created HPSLC_6875_G8130.1_78882933
hsa-miR-7852-3p tctattcACTACATt UAUGUAGU m7b Created HPSLC_6875_G8130.1_78882933

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78590583G>A COSM3736134 TCGA-AM-5820-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-219a-2-3p tgcgctCAATTCTat AGAAUUGU m7a Created HPRO6_27261_G32138.1_78882932
hsa-miR-219b-3p tgcgctCAATTCTat AGAAUUGC m7a Created HPRO6_27261_G32138.1_78882932
hsa-miR-5708 tgCGCTCAattctat AUGAGCGA m6b Created HPRO6_27261_G32138.1_78882932
hsa-miR-219a-2-3p tgcgctCAATTCTat AGAAUUGU m7a Created HPSLC_6875_G8130.1_78882933
hsa-miR-219b-3p tgcgctCAATTCTat AGAAUUGC m7a Created HPSLC_6875_G8130.1_78882933
hsa-miR-339-3p tGCGCTCAattctat UGAGCGCC m7a Created HPSLC_6875_G8130.1_78882933
hsa-miR-5708 tgCGCTCAattctat AUGAGCGA m6b Created HPSLC_6875_G8130.1_78882933

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78590189T>G COSM1608726 HCC84T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3662 tcTCATTTTtaactg GAAAAUGA m7b (m7b->m6b) HPRT3_9195_G12097.1_78882525
hsa-miR-548c-3p tctcATTTTTaactg CAAAAAUC m6b Disrupted HPRT3_9195_G12097.1_78882525

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78590181C>T COSM965391 TCGA-AP-A059-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4712-3p tattgggCTCTCATt AAUGAGAG m7b Disrupted HHFCT_53986_uc002bdy.1_8_7
hsa-miR-589-5p tattgGGTTCTCAtt UGAGAACC m8a Created HHFCT_53986_uc002bdy.1_8_7
hsa-miR-4712-3p tattgggCTCTCATt AAUGAGAG m7b Disrupted HPRT3_9195_G12097.1_78882525
hsa-miR-589-5p tattgGGTTCTCAtt UGAGAACC m8a Created HPRT3_9195_G12097.1_78882525

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78590170C>T COSM3504320 TCGA-EE-A3AE-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4797-5p ataatACTCTGTatt GACAGAGU m7b Created HHFCT_53986_uc002bdy.1_8_7
hsa-miR-496 atAATACTCtgtatt UGAGUAUU m7b (m6b->m7b) HHFCT_53986_uc002bdy.1_8_7
hsa-miR-503-3p atAATACCCtgtatt GGGGUAUU m7b (m7b->m6b) HHFCT_53986_uc002bdy.1_8_7

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78590085G>A COSM1740209 MAVER-1 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][mantle_cell_lymphoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-659-3p caGAACCAAcagctg CUUGGUUC m7b (m6b->m7b) HHFKP_51201_uc002bdy.1_3_8

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78589978C>T COSM1708432 YURUS [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4679 gatggATCACAGgtt UCUGUGAU m7b Disrupted HHFCT_53985_uc002bdy.1_7_7
hsa-miR-640 gaTGGATCAcaggtt AUGAUCCA m7b (m7b->m6b) HHFCT_53985_uc002bdy.1_7_7

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78589924C>T COSM108281 24T [cervix][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3153 ttTTTCCCatttgac GGGGAAAG m6b Disrupted HPCB3_7709_G10615.1_78882271
hsa-miR-3671 tttttccTATTTGAc AUCAAAUA m7b Created HPCB3_7709_G10615.1_78882271
hsa-miR-4496 ttTTTCCTatttgac GAGGAAAC m6b Created HPCB3_7709_G10615.1_78882271
hsa-miR-4694-3p tttttcCCATTTGac CAAAUGGA m7a Disrupted HPCB3_7709_G10615.1_78882271
hsa-miR-6124 tTTTTCCCatttgac GGGAAAAG m7a Disrupted HPCB3_7709_G10615.1_78882271

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78580904AC>A COSM1374791 TCGA-AA-3663-01 [large_intestine][caecum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-125a-3p gtggaaCACCTGaatg ACAGGUGA m6b Disrupted HHFKP_51199_uc002bdy.1_1_25
hsa-miR-3934-5p gtggaACACCTGAatg UCAGGUGU m8a Disrupted HHFKP_51199_uc002bdy.1_1_25
hsa-miR-4255 gtgGAACACTGaatg CAGUGUUC m8a Created HHFKP_51199_uc002bdy.1_1_25
hsa-miR-4276 gtggaaCACTGAatg CUCAGUGA m6b Created HHFKP_51199_uc002bdy.1_1_25
hsa-miR-6733-3p gtggaACACTGAatg UCAGUGUC m7a Created HHFKP_51199_uc002bdy.1_1_25
hsa-miR-764 gtggaaCACCTGaatg GCAGGUGC m6b Disrupted HHFKP_51199_uc002bdy.1_1_25

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78580896T>A COSM3504314 TCGA-EE-A2GC-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1273g-3p ttcgtcCAGTGGaac ACCACUGC m6b Created HHFKP_51199_uc002bdy.1_1_25
hsa-miR-181a-2-3p ttcgtcCAGTGGaac ACCACUGA m6b Created HHFKP_51199_uc002bdy.1_1_25
hsa-miR-3654 ttcGTCCAGTggaac GACUGGAC m7b Created HHFKP_51199_uc002bdy.1_1_25
hsa-miR-3692-3p ttcgtccTGTGGAAc GUUCCACA m7b Disrupted HHFKP_51199_uc002bdy.1_1_25
hsa-miR-4436b-5p ttcgtccAGTGGAac GUCCACUU m6b Created HHFKP_51199_uc002bdy.1_1_25
hsa-miR-4700-3p ttcGTCCTGTGgaac CACAGGAC m8a Disrupted HHFKP_51199_uc002bdy.1_1_25
hsa-miR-6509-3p ttcgtcCAGTGGAAc UUCCACUG m8a Created HHFKP_51199_uc002bdy.1_1_25

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78580895C>A COSM4672268 T3024 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4700-3p gttcGTCCTGTGgaa CACAGGAC m8a Disrupted HHFKP_51199_uc002bdy.1_1_25

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78580891C>T COSM3504313 TCGA-FS-A1ZZ-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1273d ATGGGTTCgtcctgt GAACCCAU m8a Disrupted HHFKP_51199_uc002bdy.1_1_25
hsa-miR-4436a atgggttTGTCCTGt GCAGGACA m7b Created HHFKP_51199_uc002bdy.1_1_25
hsa-miR-5000-3p atgggttTGTCCTGt UCAGGACA m7b Created HHFKP_51199_uc002bdy.1_1_25

Mutation Mutation ID Sample Name Cancer Type
chr15:g.78580879G>A COSM3504312 T1764 [large_intestine][rectum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3674 agaCTACAAaagatg AUUGUAGA m6b Created HHFCT_53982_uc002bdy.1_4_9
hsa-miR-3674 agaCTACAAaagatg AUUGUAGA m6b Created HHFKP_51199_uc002bdy.1_1_25

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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