SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

Transcript ID:	hsa_circ_0043960
Gene Symbol:	BRCA1
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Somatic mutations that impact miRNA target sites

Mutation		Mutation ID	Sample Name	Cancer Type
chr17:g.43124064A>CA		COSM24526	36	[haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][blast_phase_chronic_myeloid_leukaemia]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-134-5p	aagaAGTCACAaaatg	UGUGACUG	m7a	Created	HHFCT_63219_cluster-10350_30_12
hsa-miR-3118	aagaAGTCACAaaatg	UGUGACUG	m7a	Created	HHFCT_63219_cluster-10350_30_12
hsa-miR-3164	aagAAGTCACAaaatg	UGUGACUU	m8a	Created	HHFCT_63219_cluster-10350_30_12
hsa-miR-3682-5p	aAGAAGTAcaaaatg	CUACUUCU	m7b	Disrupted	HHFCT_63219_cluster-10350_30_12
hsa-miR-6505-3p	aAGAAGTCAcaaaatg	UGACUUCU	m8a	(m7a->m8a)	HHFCT_63219_cluster-10350_30_12
hsa-miR-6808-3p	aagaaGTCACAaaatg	GUGUGACC	m6b	Created	HHFCT_63219_cluster-10350_30_12
hsa-miR-6820-3p	aagAAGTCACAaaatg	UGUGACUU	m8a	Created	HHFCT_63219_cluster-10350_30_12
hsa-miR-758-3p	aagaaGTCACAAAatg	UUUGUGAC	m8a	Created	HHFCT_63219_cluster-10350_30_12

Mutation		Mutation ID	Sample Name	Cancer Type
chr17:g.43124029GA>A		COSM436670	TCGA-B6-A0X1-01	[breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Mutation		Mutation ID	Sample Name	Cancer Type
chr17:g.43124029AGA>A		COSM35893	SUM1315MO2	[breast][NS][carcinoma][ductal_carcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-3117-5p	aaatctTAGTGTCcc	AGACACUA	m7b	Created	HHHNE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-3117-5p	aaatctTAGTGTCcc	AGACACUA	m7b	Created	HHHSE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429

Mutation		Mutation ID	Sample Name	Cancer Type
chr17:g.43124027AGT>T		COSM3190162	HSJD_DIPG001	[central_nervous_system][brainstem][glioma][astrocytoma_Grade_III]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-1302	atcttagTGTCCCAt	UUGGGACA	m7b	Created	HHHNE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-3117-5p	atctTAGTGTCccat	AGACACUA	m7b	Created	HHHNE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-4298	atcttagTGTCCCAt	CUGGGACA	m7b	Created	HHHNE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-1302	atcttagTGTCCCAt	UUGGGACA	m7b	Created	HHHSE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-3117-5p	atctTAGTGTCccat	AGACACUA	m7b	Created	HHHSE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-4298	atcttagTGTCCCAt	CUGGGACA	m7b	Created	HHHSE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-1302	atcttagTGTCCCAt	UUGGGACA	m7b	Created	HHHNE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-3117-5p	atctTAGTGTCccat	AGACACUA	m7b	Created	HHHNE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-4298	atcttagTGTCCCAt	CUGGGACA	m7b	Created	HHHNE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-1302	atcttagTGTCCCAt	UUGGGACA	m7b	Created	HHHSE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-3117-5p	atctTAGTGTCccat	AGACACUA	m7b	Created	HHHSE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-4298	atcttagTGTCCCAt	CUGGGACA	m7b	Created	HHHSE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429

Mutation		Mutation ID	Sample Name	Cancer Type
chr17:g.43124016G>T		COSM3734724	1050652	[ovary][NS][carcinoma][serous_carcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Mutation		Mutation ID	Sample Name	Cancer Type
chr17:g.43124016G>A		COSM436669	TCGA-A1-A0SO-01	[breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-2115-3p	ccaTCTGATaagtca	CAUCAGAA	m6b	Created	HHHNE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-361-5p	ccaTCTGATAAgtca	UUAUCAGA	m8a	Created	HHHNE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-374a-3p	ccatCTGATAAGtca	CUUAUCAG	m8a	Created	HHHNE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-2115-3p	ccaTCTGATaagtca	CAUCAGAA	m6b	Created	HHHSE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-361-5p	ccaTCTGATAAgtca	UUAUCAGA	m8a	Created	HHHSE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-374a-3p	ccatCTGATAAGtca	CUUAUCAG	m8a	Created	HHHSE_2042_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429

Mutation		Mutation ID	Sample Name	Cancer Type
chr17:g.43115770G>T		COSM3190161	TCGA-BP-4160-01	[kidney][NS][carcinoma][clear_cell_renal_cell_carcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-3161	tggagtTTATCAagg	CUGAUAAG	m6b	Created	HHHNE_2041_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-3161	tggagtTTATCAagg	CUGAUAAG	m6b	Created	HHHSE_2041_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-3161	tggagtTTATCAagg	CUGAUAAG	m6b	Created	HHHNE_2041_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429
hsa-miR-3161	tggagtTTATCAagg	CUGAUAAG	m6b	Created	HHHSE_2041_BRCA1|NM_007299|exon_CDS|-7.02372634191907|0.012031601188429

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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