SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_001244249
Gene Symbol: APEX1
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Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr14:g.20457665A>G COSN8588396 3402_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3189-3p gCCCAAGGtttttta CCCUUGGG m7b Created HPRO6_23985_G28123.1_20925835
hsa-miR-548ac gcccaaGGTTTTTta CAAAAACC m7b Created HPRO6_23985_G28123.1_20925835
hsa-miR-548bb-3p gcccaaGGTTTTTta CAAAAACC m7b Created HPRO6_23985_G28123.1_20925835
hsa-miR-548c-3p gcccaaGATTTTTta CAAAAAUC m7b Disrupted HPRO6_23985_G28123.1_20925835
hsa-miR-548d-3p gcccaaGGTTTTTta CAAAAACC m7b Created HPRO6_23985_G28123.1_20925835
hsa-miR-548h-3p gcccaaGGTTTTTta CAAAAACC m7b Created HPRO6_23985_G28123.1_20925835
hsa-miR-548z gcccaaGGTTTTTta CAAAAACC m7b Created HPRO6_23985_G28123.1_20925835
hsa-miR-6813-3p gcCCAAGGTTtttta AACCUUGG m8a Created HPRO6_23985_G28123.1_20925835

Mutation Mutation ID Sample Name Cancer Type
chr14:g.20457577C>A COSN1639517 RK082_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HHFCT_46854_cluster-6301_6_37
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HHFCT_46854_cluster-6301_6_37
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HHFCT_46854_cluster-6301_6_37
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HHFCT_46854_cluster-6301_6_37
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HHKTA_50978_NM_001641|1321|1360|1.34130617260447|3.00376313105992
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HHKTA_50978_NM_001641|1321|1360|1.34130617260447|3.00376313105992
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HHKTA_50978_NM_001641|1321|1360|1.34130617260447|3.00376313105992
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HHKTA_50978_NM_001641|1321|1360|1.34130617260447|3.00376313105992
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HPCB3_6696_G9184.1_20925731
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HPCB3_6696_G9184.1_20925731
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HPCB3_6696_G9184.1_20925731
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HPCB3_6696_G9184.1_20925731
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HPRO6_23983_G28121.1_20925739
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HPRO6_23983_G28121.1_20925739
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HPRO6_23983_G28121.1_20925739
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HPRO6_23983_G28121.1_20925739
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HPSEF_6780_G8138.1_20925718
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HPSEF_6780_G8138.1_20925718
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HPSEF_6780_G8138.1_20925718
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HPSEF_6780_G8138.1_20925718
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HHFCT_46854_cluster-6301_6_37
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HHFCT_46854_cluster-6301_6_37
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HHFCT_46854_cluster-6301_6_37
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HHFCT_46854_cluster-6301_6_37
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HHKTA_50978_NM_001641|1321|1360|1.34130617260447|3.00376313105992
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HHKTA_50978_NM_001641|1321|1360|1.34130617260447|3.00376313105992
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HHKTA_50978_NM_001641|1321|1360|1.34130617260447|3.00376313105992
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HHKTA_50978_NM_001641|1321|1360|1.34130617260447|3.00376313105992
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HPCB3_6696_G9184.1_20925731
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HPCB3_6696_G9184.1_20925731
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HPCB3_6696_G9184.1_20925731
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HPCB3_6696_G9184.1_20925731
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HPRO6_23983_G28121.1_20925739
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HPRO6_23983_G28121.1_20925739
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HPRO6_23983_G28121.1_20925739
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HPRO6_23983_G28121.1_20925739
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HPSEF_6780_G8138.1_20925718
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HPSEF_6780_G8138.1_20925718
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HPSEF_6780_G8138.1_20925718
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HPSEF_6780_G8138.1_20925718
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HHFCT_46854_cluster-6301_6_37
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HHFCT_46854_cluster-6301_6_37
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HHFCT_46854_cluster-6301_6_37
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HHFCT_46854_cluster-6301_6_37
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HHKTA_50978_NM_001641|1321|1360|1.34130617260447|3.00376313105992
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HHKTA_50978_NM_001641|1321|1360|1.34130617260447|3.00376313105992
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HHKTA_50978_NM_001641|1321|1360|1.34130617260447|3.00376313105992
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HHKTA_50978_NM_001641|1321|1360|1.34130617260447|3.00376313105992
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HPCB3_6696_G9184.1_20925731
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HPCB3_6696_G9184.1_20925731
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HPCB3_6696_G9184.1_20925731
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HPCB3_6696_G9184.1_20925731
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HPRO6_23983_G28121.1_20925739
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HPRO6_23983_G28121.1_20925739
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HPRO6_23983_G28121.1_20925739
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HPRO6_23983_G28121.1_20925739
hsa-miR-4427 aaacacTATTCAGAg UCUGAAUA m8a Created HPSEF_6780_G8138.1_20925718
hsa-miR-4709-3p aaacaCTCTTCAgag UUGAAGAG m7b Disrupted HPSEF_6780_G8138.1_20925718
hsa-miR-5187-3p aaacactATTCAGag ACUGAAUC m6b Created HPSEF_6780_G8138.1_20925718
hsa-miR-5585-3p aaacaCTATTCAGag CUGAAUAG m8a Created HPSEF_6780_G8138.1_20925718

Mutation Mutation ID Sample Name Cancer Type
chr14:g.20457417ACT>A COSM1322743 TCGA-29-1781-01 [ovary][NS][carcinoma][serous_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4481 ttgtCCCACTCtctgtt GGAGUGGG m7b Disrupted HPRO6_23981_G28119.1_20925586
hsa-miR-4648 ttGTCCCACtctctgtt UGUGGGAC m7b (m7b->m6b) HPRO6_23981_G28119.1_20925586
hsa-miR-4693-3p ttgtccCACTCTCtgtt UGAGAGUG m7b Disrupted HPRO6_23981_G28119.1_20925586
hsa-miR-4745-5p ttgtCCCACTCtctgtt UGAGUGGG m7b Disrupted HPRO6_23981_G28119.1_20925586
hsa-miR-4797-5p ttgtcccACTCTGTt GACAGAGU m7b Created HPRO6_23981_G28119.1_20925586
hsa-miR-759 ttgtccCACTCTGtt GCAGAGUG m7b Created HPRO6_23981_G28119.1_20925586

Mutation Mutation ID Sample Name Cancer Type
chr14:g.20457416C>T COSM3814430 TCGA-AC-A23H-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1302 gtTGTCCCActctct UUGGGACA m7b (m7b->m6b) HPRO6_23981_G28119.1_20925586
hsa-miR-4298 gtTGTCCCActctct CUGGGACA m7b (m7b->m6b) HPRO6_23981_G28119.1_20925586
hsa-miR-4481 gttgtCCCACTCtct GGAGUGGG m7b Disrupted HPRO6_23981_G28119.1_20925586
hsa-miR-4648 gttGTCCCACtctct UGUGGGAC m7b Disrupted HPRO6_23981_G28119.1_20925586
hsa-miR-4693-3p gttgtccCACTCTCt UGAGAGUG m7b Disrupted HPRO6_23981_G28119.1_20925586
hsa-miR-4745-5p gttgtCCCACTCtct UGAGUGGG m7b Disrupted HPRO6_23981_G28119.1_20925586

Mutation Mutation ID Sample Name Cancer Type
chr14:g.20457319C>G COSM4830097 TCGA-UC-A7PF-01 [cervix][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-125a-3p ggCACCTGTacccca ACAGGUGA m7a (m6a->m7a) HPKTA_17913_G19337.1_20925488
hsa-miR-197-5p ggcaccTCTACCCca CGGGUAGA m7b Disrupted HPKTA_17913_G19337.1_20925488
hsa-miR-3132 ggcaccTCTACCCca UGGGUAGA m7b Disrupted HPKTA_17913_G19337.1_20925488
hsa-miR-4451 ggcacCTCTACCcca UGGUAGAG m7b Disrupted HPKTA_17913_G19337.1_20925488
hsa-miR-552-3p ggCACCTGTacccca AACAGGUG m7b (m6b->m7b) HPKTA_17913_G19337.1_20925488
hsa-miR-764 gGCACCTGtacccca GCAGGUGC m7b Created HPKTA_17913_G19337.1_20925488

Mutation Mutation ID Sample Name Cancer Type
chr14:g.20457043G>A COSM4662437 T368 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1252-3p ttgaCTCATTTGtgc CAAAUGAG m8a Created HHFCT_46851_cluster-6301_1_19
hsa-miR-4719 ttgactcATTTGTGc UCACAAAU m7b Created HHFCT_46851_cluster-6301_1_19
hsa-miR-937-5p tTGACTCAtttgtgc GUGAGUCA m7b Created HHFCT_46851_cluster-6301_1_19

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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