SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_178457
Gene Symbol: ZNF831
Description: Homo sapiens zinc finger protein 831 (ZNF831), mRNA.
Gene Location: chr20(+):57766074-57834167
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr20:g.59254921C>T 9_22814 CRC-3-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-141-3p cagccgCAGTGTTccccag
2
UAACACUG m7b Created 0.062 0.086 -1.01
hsa-miR-200a-3p cagccgCAGTGTTccccag
2
UAACACUG m7b Created 0.065 0.089 -1.19

Mutation Mutation ID Sample Name Cancer Type
chr20:g.59255866A>G COSN5975724 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-141-3p ttcccCAGTGTTccaagcc
1
UAACACUG m7b Created 0.062000 0.173000 No effect
hsa-miR-200a-3p ttcccCAGTGTTccaagcc
1
UAACACUG m7b Created 0.065000 0.176000 0.080000
hsa-miR-200b-3p ttcccCAGTATTccaagcc
3
UAAUACUG m7b Disrupted 0.214000 0.072000 0.080000
hsa-miR-200c-3p ttcccCAGTATTccaagcc
3
UAAUACUG m7b Disrupted 0.214000 0.072000 0.040000
hsa-miR-3673 ttccccagtATTCCAagcc
11
AUGGAAUG m6b Disrupted 0.091000 no TS 0.280000
hsa-miR-429 ttcccCAGTATTccaagcc
3
UAAUACUG m7b Disrupted 0.223000 0.072000 0.050000

Mutation Mutation ID Sample Name Cancer Type
chr20:g.59256191A>C COSN7099767 8067180 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-374c-3p ctgtgaCTAAGTatggtca
3
CACUUAGC m6b Disrupted 0.061000 no TS 0.610000

Mutation Mutation ID Sample Name Cancer Type
chr20:g.59256196G>A COSN4971003 SS6003302 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-591 actaagtATGGTCaaattt
2
AGACCAUG m6b Disrupted -0.345000 -0.321000 No effect
hsa-miR-625-3p actaagTATAGTCaaattt
0 GACUAUAG m7a Created NA NA No effect
hsa-miR-591 actaagtATGGTCaaattt
2
AGACCAUG m6b Disrupted -0.345000 -0.321000 No effect
hsa-miR-625-3p actaagTATAGTCaaattt
0 GACUAUAG m7a Created NA NA No effect

Mutation Mutation ID Sample Name Cancer Type
chr20:g.59256686A>G COSN7099768 8057726 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-141-5p atggcttGAAGATattccc
0 CAUCUUCC m6b Disrupted 0.092000 no TS No effect
hsa-miR-498 atgGCTTGAAgatattccc
2
UUUCAAGC m7b (m7b->m6b) 0.095000 no TS 2.280000

Mutation Mutation ID Sample Name Cancer Type
chr20:g.59256704A>G COSN5446687 RK087_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-218-1-3p ccatggGGAACCATtgcca
2
AUGGUUCC m8a Disrupted -0.157000 -0.214000 -0.020000
hsa-miR-218-2-3p ccatgggGAACCATtgcca
1
CAUGGUUC m7b Disrupted 0.122000 no TS -0.030000
hsa-miR-642b-5p ccatgGGGAACCattgcca
0 GGUUCCCU m7a Disrupted NA NA 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr20:g.59257297C>G 12_89 NA [upper_aerodigestive_tract][mouth][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1206 actttatATGAACAtgaat
0 UGUUCAUG m7a Created 0.056 0.095 1.59
hsa-miR-5007-3p actttATATGAacatgaat
0 AUCAUAUG m6b Created 0.026 0.119 -0.18
hsa-miR-5007-3p actttATATGAacatgaat
2
AUCAUAUG m6b Created 0.026000 0.119000 -0.180000

Mutation Mutation ID Sample Name Cancer Type
chr20:g.59257370A>T COSN1878074 RK031_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2116-3p atgaccctATGGGAGctgg
0 CCUCCCAU m7b Created no TS 0.022000 -0.220000
hsa-miR-4287 atgaccctAAGGGAGctgg
0 UCUCCCUU m7b Disrupted 0.008000 0.006000 1.620000
hsa-miR-4685-3p atgaccctAAGGGAGctgg
0 UCUCCCUU m7b Disrupted 0.064000 0.015000 No effect
hsa-miR-2116-3p atgaccctATGGGAGctgg
0 CCUCCCAU m7b Created no TS 0.022 -0.22
hsa-miR-4287 atgaccctAAGGGAGctgg
0 UCUCCCUU m7b Disrupted 0.008 0.006 1.62
hsa-miR-4685-3p atgaccctAAGGGAGctgg
0 UCUCCCUU m7b Disrupted 0.064 0.015 No effect

Mutation Mutation ID Sample Name Cancer Type
chr20:g.59258034C>A COSN1878075 RK133_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3173-3p aactggaatCCTCCTTctt
4
AAAGGAGG m7b (m7b->m6c) 0.026000 0.124000 0.020000
hsa-miR-496 aactggAATACTCcttctt
0 UGAGUAUU m7b Created no TS 0.015000 -1.310000
hsa-miR-3173-3p aactggaatCCTCCTTctt
0 AAAGGAGG m7b (m7b->m6c) 0.026 0.124 0.02
hsa-miR-496 aactggAATACTCcttctt
0 UGAGUAUU m7b Created no TS 0.015 -1.31

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table

Location SNP ID Ancestral
Allele
Allele miR ID Conservation miRSite FuncClass Validation context+
score change
59254921 rs78986299 C C hsa-miR-1292-5p
0 ccgcagCGTTCCC
Disrupted
N
-0.158
T hsa-miR-141-3p
hsa-miR-200a-3p
1
1
ccgCAGTGTTccc
ccgCAGTGTTccc
Created
Created
N
N
0.024
0.024
59255010 rs73916204 G G hsa-miR-591
2
caaATGGTCAacg
Disrupted
N
-0.103
A hsa-miR-579-3p
hsa-miR-664b-3p
1
1
CAAATGAtcaacg
CAAATGAtcaacg
Created
Created
N
N
0.021
0.012
59255693 rs6092761 C C hsa-miR-1247-5p
9
tcgtGACGGGAgc
Disrupted
N
-0.124
T hsa-miR-2116-3p
hsa-miR-6884-3p
8
8
tcgtgATGGGAGc
tcGTGATGGgagc
Created
Created
N
N
-0.02
-0.008
59256367 rs138363135 G G hsa-miR-2681-5p
hsa-miR-4287
hsa-miR-4685-3p
hsa-miR-4777-3p
2
5
5
2
aagggaGGTAAAA
AAGGGAGgtaaaa
AAGGGAGgtaaaa
aaggGAGGTAAaa
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
0.011
0.006
0.015
-0.02
T hsa-miR-188-5p
hsa-miR-6866-3p
5
5
AAGGGATgtaaaa
AAGGGATgtaaaa
Created
Created
N
N
-0.003
-0.022
59257445 rs76671897 C C hsa-miR-1206
hsa-miR-4445-5p
hsa-miR-5186
hsa-miR-6853-3p
3
6
6
3
aATGAACAatctc
aatgAACAATCtc
aatgaaCAATCTC
AATGAACAatctc
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
0.044
-0.011
-0.036
0.115
T hsa-miR-664a-3p
3
AATGAATAatctc
Created
N
0.22

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