SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_014897
Gene Symbol: ZNF652
Description: Homo sapiens zinc finger protein 652 (ZNF652), transcript variant 1, mRNA.
Gene Location: chr17(-):47366567-47439835
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr17:g.49289215A>- ICGC_ssm_v3_95560 HCC3T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3140-3p aaaaaaAAAAGCagccata
 0 AGCUUUUG m6b Disrupted -0.078000 -0.075000 No effect
hsa-miR-647 aaaaaaaaaGCAGCCAta
 0 GUGGCUGC m7b (m6b->m7b) -0.438000 -0.434000 -0.140000


Mutation Mutation ID Sample Name Cancer Type
chr17:g.49289227A>T COSN1197986 HCC48T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr17:g.49289228A>G COSN1197987 HCC48T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2681-5p caaaGTAAAAaaaaaaaaa
 11
 GUUUUACC m6b Disrupted -0.062000 no TS No effect
hsa-miR-2681-5p caaaGTAAAAaaaaaaaaa
 0 GUUUUACC m6b Disrupted -0.062 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr17:g.49290174A>C COSN6657650 CHC322T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1294 tgcctggccACCTCACccc
 0 UGUGAGGU m7b (m7b->m6b) 0.044000 no TS 0.770000
hsa-miR-1914-3p tgcctggcCCCCTCacccc
 0 GGAGGGGU m6b Created no TS -0.055000 -0.010000
hsa-miR-4435 tgcCTGGCCAcctcacccc
 4
 AUGGCCAG m7b (m7b->m6c) -0.298000 -0.276000 No effect
hsa-miR-4640-5p tgcCTGGCCCcctcacccc
 0 UGGGCCAG m7b (m6c->m7b) no TS -0.078000 -0.080000
hsa-miR-4726-5p tgcCTGGCCCcctcacccc
 0 AGGGCCAG m7b (m6c->m7b) no TS -0.050000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr17:g.49291935A>G COSN15456919 AOCS-164-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-136-3p tgtttGATGATGaataaat
 0 CAUCAUCG m7a Disrupted NA NA 0.110000
hsa-miR-664-3p tgtttgatgATGAATAaat
 5
 UAUUCAUU m7a (m7a->m6a) 0.229000 0.130000 -0.390000

Mutation Mutation ID Sample Name Cancer Type
chr17:g.49293107C>G COSN4769317 tumor_4139696 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-301a-5p gtatgGTCAGAGgttcctg
 10
 GCUCUGAC m7b Created -0.025000 -0.020000 No effect
hsa-miR-4256 gtatGGTCAGAggttcctg
 3
 AUCUGACC m7b Created -0.032000 -0.082000 No effect
hsa-miR-649 gtatggtcACAGGTTcctg
 4
 AAACCUGU m7b Disrupted 0.063000 0.022000 0.080000

Mutation Mutation ID Sample Name Cancer Type
chr17:g.49293192T>G COSN6105355 RK119_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-10b-3p gataGAATCTGTattgtag
 2
 ACAGAUUC m8a Disrupted -0.001000 0.082000 2.570000


Mutation Mutation ID Sample Name Cancer Type
chr17:g.49293442T>A COSN6105356 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr17:g.49294551G>A COSN8837990 AOCS-137-1-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2114-3p gtcagatAGGCTCattcgg
 7
 CGAGCCUC m6b Disrupted -0.178000 -0.138000 No effect
hsa-miR-627 gtcagatAGACTCAttcgg
 8
 GUGAGUCU m7b Created -0.190000 -0.233000 No effect
hsa-miR-924 gtcagatAGACTCattcgg
 10
 AGAGUCUU m6b Created -0.111000 -0.110000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr17:g.49295158G>A ICGC_8C7827CA-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-143-5p cgccACTGCACtccagcct
 0 GGUGCAGU m7b Created no TS 0.08 -0.29

Mutation Mutation ID Sample Name Cancer Type
chr17:g.49295537T>C COSN6105357 RK119_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3140-5p atATTCAGGTagtcatctt
 9
 ACCUGAAU m8a (m8a->m7b) -0.057000 -0.030000 -0.430000
hsa-miR-5002-3p atattcaGGCAGTCAtctt
 0 UGACUGCC m8a Created no TS -0.197000 -2.970000

Mutation Mutation ID Sample Name Cancer Type
chr17:g.49295698G>C ICGC_8C782C98-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-149-3p tcagCCTCCCaaagtgctg
 0 AGGGAGGG m6b Created 0.017 0.017 No effect
hsa-miR-30b-3p tcagCCTCCCAaagtgctg
 0 CUGGGAGG m7b Created -0.032 -0.005 No effect
hsa-miR-30c-1-3p tcagcCTCCCAaagtgctg
 0 CUGGGAGA m6b Created no TS 0.047 No effect
hsa-miR-30c-2-3p tcagcCTCCCAaagtgctg
 0 CUGGGAGA m6b Created no TS 0.044 No effect
hsa-miR-3122 tcagccTCCCAAagtgctg
 0 GUUGGGAC m6b Created no TS 0.08 No effect
hsa-miR-3689a-3p tcagCCTCCCAaagtgctg
 0 CUGGGAGG m7b Created -0.041 -0.014 No effect
hsa-miR-3689b-3p tcagCCTCCCAaagtgctg
 0 CUGGGAGG m7b Created -0.041 -0.014 No effect
hsa-miR-3689c tcagCCTCCCAaagtgctg
 0 CUGGGAGG m7b Created -0.041 -0.014 No effect
hsa-miR-4728-5p tcagCCTCCCAaagtgctg
 0 UGGGAGGG m7a Created 0.01 0.017 No effect

Mutation Mutation ID Sample Name Cancer Type
chr17:g.49296679T>A COSN1197988 HCC122T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-217 aggTGCAGTAatagcacac
 0 UACUGCAU m7a (m6b->m7a) no TS 0.024000 0.010000
hsa-miR-509-3-5p aggTGCAGTAatagcacac
 0 UACUGCAG m7a (m6b->m7a) -0.111000 -0.071000 No effect
hsa-miR-509-5p aggTGCAGTAatagcacac
 0 UACUGCAG m7a (m6b->m7a) -0.120000 -0.083000 No effect
hsa-miR-217 aggTGCAGTAatagcacac
 0 UACUGCAU m7a (m6b->m7a) no TS 0.024 0.01
hsa-miR-509-3-5p aggTGCAGTAatagcacac
 0 UACUGCAG m7a (m6b->m7a) -0.111 -0.071 No effect
hsa-miR-509-5p aggTGCAGTAatagcacac
 0 UACUGCAG m7a (m6b->m7a) -0.12 -0.083 No effect

Mutation Mutation ID Sample Name Cancer Type
chr17:g.49296697G>T COSN1197989 HCC35T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1273g-3p agtGCAGTGGctattcaca
 1
 ACCACUGC m7b (m7b->m6c) -0.123000 -0.051000 0.520000
hsa-miR-3117-5p agtgcAGTGTCTattcaca
 2
 AGACACUA m7a Created -0.108000 -0.108000 No effect
hsa-miR-4252 agtgCAGTGGCtattcaca
 8
 GGCCACUG m7b Disrupted -0.054000 -0.020000 No effect
hsa-miR-449b-3p agtgcaGTGGCTattcaca
 6
 CAGCCACA m6b Disrupted -0.250000 -0.253000 No effect
hsa-miR-1273g-3p agtGCAGTGGctattcaca
 0 ACCACUGC m7b (m7b->m6c) -0.123 -0.051 0.52
hsa-miR-3117-5p agtgcAGTGTCTattcaca
 0 AGACACUA m7a Created -0.108 -0.108 No effect
hsa-miR-4252 agtgCAGTGGCtattcaca
 0 GGCCACUG m7b Disrupted -0.054 -0.02 No effect
hsa-miR-449b-3p agtgcaGTGGCTattcaca
 0 CAGCCACA m6b Disrupted -0.25 -0.253 No effect

Mutation Mutation ID Sample Name Cancer Type
chr17:g.49296729T>C COSN6105358 RK163_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1245b-5p gagacAAGGCCTtgctatg
 0 UAGGCCUU m7b Created no TS -0.025000 -0.030000
hsa-miR-3142 gagacAAGGCCTTgctatg
 0 AAGGCCUU m8a Created no TS 0.003000 -0.020000
hsa-miR-3922-5p gagacaaGGCCTTGctatg
 0 UCAAGGCC m7b Created no TS -0.088000 No effect
hsa-miR-4312 gagACAAGGCCttgctatg
 0 GGCCUUGU m8a Created no TS 0.017000 No effect
hsa-miR-451b gagacaaggTCTTGCTAtg
 1
 UAGCAAGA m8a (m8a->m7a) 0.079000 0.058000 0.080000
hsa-miR-4696 gagacaagGTCTTGCtatg
 9
 UGCAAGAC m7b Disrupted 0.040000 0.046000 0.120000
hsa-miR-4708-3p gagacaagGCCTTGCTatg
 0 AGCAAGGC m8a Created -0.046000 -0.148000 -0.080000

Mutation Mutation ID Sample Name Cancer Type
chr17:g.49296999C>T COSN7437236 8057484 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-548c-3p accagcATTTTTaggcgat
 1
 CAAAAAUC m6b Created 2.444000 2.698000 -0.480000


Mutation Mutation ID Sample Name Cancer Type
chr17:g.49297348T>G COSN5220478 SS6003323 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr17:g.49297628T>A COSN5417243 RK134_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3655 ttcagaGACAAGatgtatc
 3
 GCUUGUCG m6b Created -0.024000 -0.076000 -0.020000
hsa-miR-4474-5p ttcaGAGACTAgatgtatc
 0 UUAGUCUC m7b Disrupted -0.093000 0.011000 1.310000
hsa-miR-554 ttcagaGACTAGatgtatc
 7
 GCUAGUCC m6b Disrupted -0.073000 no TS 0.110000
hsa-miR-593-3p ttCAGAGACAagatgtatc
 2
 UGUCUCUG m8a (m7b->m8a) -0.104000 -0.181000 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
49289214 rs72835477 G G hsa-miR-3140-3p
hsa-miR-604
hsa-miR-647
hsa-miR-6762-3p
0 aaAAAAGCAgcca
aaaaaaGCAGCCA
aaaaaaGCAGCCA
aaaaaAGCAGCCA
 Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
 -0.078
-0.303
-0.425
-0.63
C hsa-miR-29b-1-5p
hsa-miR-3652
hsa-miR-4430
hsa-miR-4505
hsa-miR-5787
hsa-miR-6842-3p
0 aaaAAACCAGcca
aaaaaaCCAGCCA
aaaaaaCCAGCCA
aaaaaaCCAGCCA
aaaaaaCCAGCCA
aaaaaaCCAGCCA
 Created
Created
Created
Created
Created
Created
N
N
N
N
N
N
 -0.245
-0.251
-0.251
-0.246
-0.246
-0.376
49289215 rs201606438 - AAAAA hsa-miR-3140-3p
hsa-miR-6762-3p
0 aaaaaaaAAAAGCAgccata
aaaaaaaaaaAGCAGCCAta
 Unknown
Unknown
N
N
 -0.006
-0.008
- hsa-miR-135a-5p
hsa-miR-135b-5p
hsa-miR-604
hsa-miR-647
hsa-miR-889-5p
0 aaaaaagcAGCCATA
aaaaaagcAGCCATA
aaaaaaGCAGCCAta
aaaaaaGCAGCCAta
aaaaaagCAGCCATA
 Unknown
Unknown
Unknown
Unknown
Unknown
N
N
N
N
N
 0.007
0.007
0.004
0.01
0.011
49289566 rs143456652 C C hsa-miR-1270
hsa-miR-4531
hsa-miR-4683
hsa-miR-620
6
6
7
6
 gaATCTCCAAagg
gaaTCTCCAAagg
gaATCTCCAaagg
gaATCTCCAAagg
 Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
 -0.232
-0.057
-0.069
-0.211
G hsa-miR-10b-3p
hsa-miR-1273h-3p
hsa-miR-3121-5p
hsa-miR-3678-3p
hsa-miR-6516-5p
4
6
1
6
7
 GAATCTGcaaagg
gaaTCTGCAAagg
gaatctGCAAAGG
gaaTCTGCAAagg
gaatCTGCAAAgg
 Created
Created
Created
Created
Created
N
N
N
N
N
 -0.059
-0.064
-0.214
-0.068
-0.039
49290174 rs3179840 C A hsa-miR-1294
hsa-miR-4435
hsa-miR-6134
hsa-miR-6815-5p
hsa-miR-6865-5p
hsa-miR-7854-3p
0 ctggccACCTCAC
CTGGCCAcctcac
ctggCCACCTCAc
ctgGCCACCTcac
ctgGCCACCTcac
ctggcCACCTCAc
 Created
Created
Created
Created
Created
Created
N
N
N
N
N
N
 0.044
-0.022
-0.07
-0.057
-0.057
-0.017
C hsa-miR-1914-3p
hsa-miR-3184-5p
hsa-miR-423-5p
hsa-miR-4640-5p
hsa-miR-4726-5p
hsa-miR-5194
hsa-miR-6734-5p
hsa-miR-6738-5p
hsa-miR-6762-5p
hsa-miR-6805-5p
hsa-miR-6845-5p
0 ctggcCCCCTCAc
ctggcCCCCTCAc
ctggcCCCCTCAc
CTGGCCCcctcac
CTGGCCCcctcac
ctggcCCCCTCAc
ctggcCCCCTCAc
ctggcCCCCTCAc
cTGGCCCCctcac
ctgGCCCCCTcac
cTGGCCCCctcac
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
N
N
N
N
N
 -0.055
-0.046
-0.043
-0.078
-0.05
-0.049
-0.008
-0.055
-0.111
-0.097
-0.121
49291940 rs4794037 T
C hsa-miR-136-3p
9
 tatgttCGATGAT
 Created
N
 -0.062
49293543 rs184481279 C C hsa-miR-3202
hsa-miR-4533
hsa-miR-493-3p
hsa-miR-6079
10
10
10
8
 gaCCTTCCAaccc
gaCCTTCCAaccc
GACCTTCcaaccc
gacCTTCCAAccc
 Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
 0.03
0.044
-0.013
0.054
G hsa-miR-4684-3p
hsa-miR-4708-3p
8
10
 gaccTTGCAACcc
gaCCTTGCAaccc
 Created
Created
N
N
 0.092
-0.007
49295017 rs34670347 - - hsa-miR-627-5p
hsa-miR-8081
hsa-miR-924
hsa-miR-937-5p
8
8
10
8
 ttaAGACTCAAac
ttaaGACTCAAAc
ttAAGACTCAaac
ttaaGACTCAAac
 Unknown
Unknown
Unknown
Unknown
N
N
N
N
 -0.058
0.007
-0.042
0.005
C hsa-miR-1304-5p
9
 ttaagaCCTCAAAc
 Unknown
N
 0.043

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