SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001135590
Gene Symbol: ZNF577
Description: Homo sapiens zinc finger protein 577 (ZNF577), transcript variant 2, mRNA.
Gene Location: chr19(-):52374550-52391189
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr19:g.51871386T>C ICGC_8ECA4076-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-204-3p cctgtaaTCCCAGCacttt
0 GCUGGGAA m7a Created -0.152 -0.152 No effect
hsa-miR-4663 cctgtaatCTCAGCacttt
0 AGCUGAGC m6b Disrupted -0.136 no TS 0.65
hsa-miR-5089 cctgtAATCCCAgcacttt
0 GUGGGAUU m7b Created no TS -0.104 No effect
hsa-miR-5186 cctgtAATCTCagcacttt
0 AGAGAUUG m6b Disrupted -0.027 no TS No effect
hsa-miR-5589-5p cctgtaatCCCAGCacttt
0 GGCUGGGU m6b Created no TS -0.173 -0.35

Mutation Mutation ID Sample Name Cancer Type
chr19:g.51871614G>C COSN8552999 tumor_4163639 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][diffuse_large_B_cell_lymphoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3662 gtatgttaaCATTTTattc
0 GAAAAUGA m6b Created no TS 0.027000 No effect
hsa-miR-4668-3p gtatgttaaGATTTTattc
1
GAAAAUCC m6b Disrupted -0.003000 no TS -0.190000

Mutation Mutation ID Sample Name Cancer Type
chr19:g.51872470A>T COSN8606234 1255_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1266 ttatatCCCTGAGagctca
0 CCUCAGGG m7b Created no TS -0.443000 -0.110000
hsa-miR-204-3p ttataTCCCAGagagctca
1
GCUGGGAA m6b Disrupted -0.152000 no TS No effect
hsa-miR-211-3p ttataTCCCTGagagctca
0 GCAGGGAC m6b Created no TS -0.161000 0.610000
hsa-miR-3191-5p ttatatcCCAGAGAGctca
1
CUCUCUGG m8a Disrupted -0.286000 -0.124000 No effect
hsa-miR-326 ttatatCCCAGAGagctca
1
CCUCUGGG m7b Disrupted -0.423000 no TS -1.200000
hsa-miR-330-5p ttatatCCCAGAGAgctca
1
UCUCUGGG m8a Disrupted -0.433000 no TS -1.150000
hsa-miR-4314 ttataTCCCAGAGagctca
1
CUCUGGGA m8a Disrupted -0.249000 no TS No effect
hsa-miR-4441 ttataTCCCTGagagctca
0 ACAGGGAG m6b Created no TS -0.148000 No effect
hsa-miR-4518 ttatatCCCTGAGagctca
0 GCUCAGGG m7b Created no TS -0.475000 -6.320000
hsa-miR-4646-5p ttataTCCCAGagagctca
1
ACUGGGAA m6b Disrupted -0.162000 no TS 1.580000
hsa-miR-769-3p ttatATCCCAGagagctca
0 CUGGGAUC m7a Disrupted NA NA -2.400000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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