SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_014951
Gene Symbol: ZNF365
Description: Homo sapiens zinc finger protein 365 (ZNF365), transcript variant A, mRNA.
Gene Location: chr10(+):64133915-64162217
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr10:g.62399800G>A COSN1496903 RK051_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-29a-3p agggtgggTGGTGCTggac
 2
 UAGCACCA m7b Disrupted 0.000000 no TS No effect
hsa-miR-29b-3p agggtgggTGGTGCTggac
 2
 UAGCACCA m7b Disrupted 0.000000 no TS No effect
hsa-miR-29c-3p agggtgggTGGTGCTggac
 2
 UAGCACCA m7b Disrupted 0.000000 no TS No effect
hsa-miR-3065-3p agggtgggtGGTGCTGgac
 2
 UCAGCACC m7b (m7b->m6c) 0.000000 -0.034000 No effect
hsa-miR-4999-3p agggtgGGTAGTGctggac
 0 UCACUACC m7b Created no TS 0.000000 No effect
hsa-miR-29a-3p agggtgggTGGTGCTggac
 0 UAGCACCA m7b Disrupted 0 no TS No effect
hsa-miR-29b-3p agggtgggTGGTGCTggac
 0 UAGCACCA m7b Disrupted 0 no TS No effect
hsa-miR-29c-3p agggtgggTGGTGCTggac
 0 UAGCACCA m7b Disrupted 0 no TS No effect
hsa-miR-3065-3p agggtgggtGGTGCTGgac
 0 UCAGCACC m7b (m7b->m6c) 0 -0.034 No effect
hsa-miR-4999-3p agggtgGGTAGTGctggac
 0 UCACUACC m7b Created no TS 0 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.62399861C>A COSN8716111 AOCS-091-3-0 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3617 cagtaATGTCTTTctggaa
 1
 AAAGACAU m8a Disrupted -0.212000 -0.080000 No effect
hsa-miR-641 cagtaATGTCTTTctggaa
 1
 AAAGACAU m8a Disrupted -0.203000 -0.080000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.62399878A>G COSN5880513 RK154_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1 aaACATTCCAtagtaagac
 2
 UGGAAUGU m8a (m8a->m7a) -0.367000 -0.200000 No effect
hsa-miR-206 aaACATTCCAtagtaagac
 2
 UGGAAUGU m8a (m8a->m7a) -0.357000 -0.191000 No effect
hsa-miR-3669 aaacATTCCGTagtaagac
 1
 ACGGAAUA m7a Created -0.137000 -0.137000 No effect
hsa-miR-3673 aaaCATTCCATagtaagac
 2
 AUGGAAUG m8a Disrupted -0.198000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.62400432C>A COSN6978275 8014187 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-15a-3p ttttggTGGCCTagatgca
 2
 CAGGCCAU m6b Disrupted -0.302000 -0.153000 No effect
hsa-miR-4717-5p ttttgGTGGCCTAgatgca
 2
 UAGGCCAC m8a Disrupted -0.357000 no TS No effect
hsa-miR-554 ttttggtGGACTAGatgca
 0 GCUAGUCC m7b Created no TS -0.322000 -0.080000
hsa-miR-5704 ttttggTGGCCTAgatgca
 2
 UUAGGCCA m7b Disrupted -0.162000 no TS 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.62400472G>A COSN1496904 RK177_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4426 acctctgCCATCTTCtttg
 0 GAAGAUGG m8a Created no TS -0.023000 0.130000
hsa-miR-4647 acctctgCCATCTTCtttg
 0 GAAGAUGG m8a Created no TS -0.051000 0.150000
hsa-miR-4662b acctctgCCATCTTctttg
 0 AAAGAUGG m7b Created no TS -0.032000 0.120000


Mutation Mutation ID Sample Name Cancer Type
chr10:g.62400652C>T COSN6978276 8058184 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr10:g.62401073A>G COSN1496905 RK100_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2276 ctCTTGCAGAgtttacaag
 0 UCUGCAAG m8a (m8a->m7a) -0.062000 -0.020000 No effect
hsa-miR-618 ctcttgcAGAGTTTacaag
 4
 AAACUCUA m7a Disrupted -0.199000 -0.199000 1.050000
hsa-miR-2276 ctCTTGCAGAgtttacaag
 0 UCUGCAAG m8a (m8a->m7a) -0.062 -0.02 No effect
hsa-miR-618 ctcttgcAGAGTTTacaag
 0 AAACUCUA m7a Disrupted -0.199 -0.199 1.05

Mutation Mutation ID Sample Name Cancer Type
chr10:g.62401118C>A COSN8187934 PCSI_0218_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3138 taatttTGTCCACAaatat
 0 UGUGGACA m8a Disrupted -0.634000 -0.398000 No effect
hsa-miR-3177-5p taatttTGTACACAaatat
 0 UGUGUACA m8a Created no TS -0.173000 -0.010000
hsa-miR-4752 taattttgTCCACAAatat
 12
 UUGUGGAU m7a Disrupted -0.118000 -0.041000 0.030000
hsa-miR-4800-5p taattttGTCCACaaatat
 0 AGUGGACC m6b Disrupted -0.299000 -0.181000 No effect
hsa-miR-5010-3p taattttgtACACAAAtat
 2
 UUUUGUGU m7b (m6c->m7b) -0.071000 -0.136000 -0.640000
hsa-miR-599 taattttgtACACAAatat
 3
 GUUGUGUC m6b Created -0.032000 -0.034000 -0.170000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.62401383T>A COSN8716112 AOCS-112-1-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4503 agcagtTGCTTAAAatgcc
 1
 UUUAAGCA m8a Disrupted -0.041000 no TS 0.030000
hsa-miR-491-3p agcagtTGCATAAaatgcc
 0 CUUAUGCA m7b Created no TS -0.058000 -0.020000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.62401469C>G 0_368 Small cell lung cancer
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3609 gaatctTCACTTTGacttt
 14
 CAAAGUGA m8a Disrupted 0.103 0.106 0.43
hsa-miR-3973 gaatcttcACTTTGacttt
 17
 ACAAAGUA m6b Disrupted 0.027 no TS 0.32
hsa-miR-520g gaatcttCACTTTGacttt
 14
 ACAAAGUG m7b Disrupted 0.011 0.053 1.02
hsa-miR-520h gaatcttCACTTTGacttt
 14
 ACAAAGUG m7b Disrupted 0.011 0.053 0.05
hsa-miR-548ah-5p gaatctTCACTTTgacttt
 16
 AAAAGUGA m7b Disrupted 0.065 0.059 0.02

Mutation Mutation ID Sample Name Cancer Type
chr10:g.62402135G>C COSN5289168 RK140_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4521 ttgaCCTTAGagttaaggc
 3
 GCUAAGGA m6b Disrupted -0.260000 -0.182000 0.290000
hsa-miR-5684 ttgacctTAGAGTTaaggc
 0 AACUCUAG m7a Disrupted NA NA No effect
hsa-miR-618 ttgacctTAGAGTTaaggc
 4
 AAACUCUA m7b Disrupted -0.199000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.62402206G>T COSN8716113 AOCS-152-1-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-136-5p tgaAATGGAGagtagattt
 1
 ACUCCAUU m7b (m7b->m6b) -0.366000 -0.032000 0.090000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.62402227T>A COSN8716114 AOCS-076-1-3 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3671 tttTATTTGActtgtaggg
 8
 AUCAAAUA m7b (m6b->m7b) 0.057000 -0.034000 -1.930000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.62402234G>T COSN8716115 AOCS-152-1-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-300 tgtCTTGTATggaagaaat
 0 UAUACAAG m7b (m6b->m7b) no TS -0.095000 -15.340000
hsa-miR-3162-3p tgtcttGTAGGGAagaaat
 2
 UCCCUACC m7a Disrupted -0.201000 no TS 4.160000
hsa-miR-381 tgtCTTGTATggaagaaat
 0 UAUACAAG m7b (m6b->m7b) no TS -0.113000 -12.170000
hsa-miR-587 tgtcttgTATGGAAgaaat
 0 UUUCCAUA m7b Created no TS -0.099000 -1.180000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.62402369G>T COSN6978277 8057726 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-let-7a-2-3p agtTGTACAGaagttggaa
 0 CUGUACAG m7a (m7a->m6a) NA NA -0.480000
hsa-let-7g-3p agtTGTACAGaagttggaa
 0 CUGUACAG m7a (m7a->m6a) NA NA -0.480000
hsa-miR-3182 agttgtACAGAAGttggaa
 4
 GCUUCUGU m7b Disrupted -0.144000 no TS 0.040000
hsa-miR-3686 agttgTACAGAagttggaa
 4
 AUCUGUAA m6b Disrupted -0.388000 -0.311000 No effect
hsa-miR-3924 agttgTACATAagttggaa
 0 AUAUGUAU m6b Created -0.055000 -0.119000 -2.400000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
62400472 rs148627158 G
A hsa-miR-4426
hsa-miR-4647
hsa-miR-4662b
2
2
2
 tctgCCATCTTct
tctgCCATCTTct
tctgCCATCTTct
 Created
Created
Created
N
N
N
 -0.023
-0.051
-0.032
62400796 rs76598947 C T hsa-miR-3609
hsa-miR-3612
hsa-miR-520g-3p
hsa-miR-520h
hsa-miR-548ah-5p
hsa-miR-650
5
8
5
5
5
8
 TCACTTTgcctcc
tcacttTGCCTCC
tCACTTTGcctcc
tCACTTTGcctcc
TCACTTTgcctcc
tcacttTGCCTCC
 Created
Created
Created
Created
Created
Created
N
N
N
N
N
N
 0.106
-0.112
0.053
0.053
0.059
-0.093

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