SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_005095
Gene Symbol: ZMYM4
Description: Homo sapiens zinc finger, MYM-type 4 (ZMYM4), mRNA.
Gene Location: chr1(+):35734567-35887545
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr1:g.35420029G>T COSN1444261 RK194_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3183 cttAGAGAGGtagctttgg
 12
 GCCUCUCU m7b (m7b->m6b) -0.217000 no TS 0.410000
hsa-miR-4723-3p cttAGAGAGGtagctttgg
 12
 CCCUCUCU m7b (m7b->m6b) -0.198000 no TS 0.760000
hsa-miR-618 cttagAGAGTTagctttgg
 0 AAACUCUA m6b Created no TS -0.069000 -0.070000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.35420250G>T COSN14857354 LP6007438-DNA_A01 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3182 aggACAGAAGCttttgcca
 0 GCUUCUGU m8a Disrupted 0.003000 no TS 0.090000
hsa-miR-4778-5p aggACAGAATcttttgcca
 0 AAUUCUGU m7b (m6b->m7b) no TS 0.010000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr1:g.35421142A>G COSN10047809 C0074T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3662 gggtatcTCATTTTttagg
 2
 GAAAAUGA m7b Disrupted 0.267000 0.178000 No effect
hsa-miR-548ad gggtatcTCGTTTTttagg
 0 GAAAACGA m7b Created no TS -0.040000 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
35420111 rs55850358 T
T hsa-miR-3664-5p
hsa-miR-4764-3p
hsa-miR-618
7
8
8
 ACAGAGTtaagag
acaGAGTTAAgag
acAGAGTTAagag
 Disrupted
Disrupted
Disrupted
N
N
N
 -0.174
-0.04
-0.059

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