| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_020338 |
|---|---|
| Gene Symbol: | ZMIZ1 |
| Description: | Homo sapiens zinc finger, MIZ-type containing 1 (ZMIZ1), mRNA. |
| Gene Location: | chr10(+):80828791-81076285 |
| Browse Associations | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr10:g.79313043->T | ICGC_ssm_v3_126842 | HCC62T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4655-5p |
ccagCCCGGTaagagggca |
1 |
CACCGGGG | m6b | Disrupted | -0.228000 | no TS | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr10:g.79313228G>T | COSN1123037 | HCC66T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4508 |
atggGCCCCGagccttgga |
0 | GCGGGGCU | m6b | Disrupted | -0.182000 | no TS | No effect | |
| hsa-miR-5090 |
atggGCCCCGagccttgga |
0 | CCGGGGCA | m6b | Disrupted | -0.346000 | -0.159000 | No effect | |
| hsa-miR-4508 |
atggGCCCCGagccttgga |
0 | GCGGGGCU | m6b | Disrupted | -0.182 | no TS | No effect | |
| hsa-miR-5090 |
atggGCCCCGagccttgga |
0 | CCGGGGCA | m6b | Disrupted | -0.346 | -0.159 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr10:g.79313351G>C | COSN4695230 | PD3945a | [breast][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr10:g.79313675G>A | COSN15227582 | LP6005334-DNA_E03 | [oesophagus][NS][carcinoma][adenocarcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-744-3p |
ttttaaacaGCAACAattt |
0 | CUGUUGCC | m6b | Disrupted | -0.064000 | no TS |
1.190000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr10:g.79313906A>G | COSN1123038 | HCC74T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1273g-3p |
cccaggGCAGTGGTgtctg |
0 | ACCACUGC | m8a | Created | no TS | 0.030000 |
-0.010000 |
|
| hsa-miR-18a-3p |
cccAGGGCAGTggtgtctg |
0 | ACUGCCCU | m8a | Created | -0.047000 | -0.057000 |
-0.090000 |
|
| hsa-miR-4317 |
cccagGGCAATGgtgtctg |
2 |
ACAUUGCC | m7b | Disrupted | 0.035000 | no TS |
-0.299000 |
|
| hsa-miR-874 |
ccCAGGGCAGtggtgtctg |
2 |
CUGCCCUG | m8a | (m7a->m8a) | -0.081000 | 0.011000 |
-0.030000 |
|
| hsa-miR-1273g-3p |
cccaggGCAGTGGTgtctg |
0 | ACCACUGC | m8a | Created | no TS | 0.030000 |
-0.010000 |
|
| hsa-miR-18a-3p |
cccAGGGCAGTggtgtctg |
0 | ACUGCCCU | m8a | Created | -0.047000 | -0.057000 |
-0.090000 |
|
| hsa-miR-4317 |
cccagGGCAATGgtgtctg |
2 |
ACAUUGCC | m7b | Disrupted | 0.035000 | no TS |
-0.299000 |
|
| hsa-miR-874 |
ccCAGGGCAGtggtgtctg |
2 |
CUGCCCUG | m8a | (m7a->m8a) | -0.081000 | 0.011000 |
-0.030000 |
|
| hsa-miR-1273g-3p |
cccaggGCAGTGGTgtctg |
0 | ACCACUGC | m8a | Created | no TS | 0.03 |
-0.01 |
|
| hsa-miR-18a-3p |
cccAGGGCAGTggtgtctg |
0 | ACUGCCCU | m8a | Created | -0.047 | -0.057 |
-0.09 |
|
| hsa-miR-4317 |
cccagGGCAATGgtgtctg |
2 |
ACAUUGCC | m7b | Disrupted | 0.035 | no TS |
-0.299 |
|
| hsa-miR-874 |
ccCAGGGCAGtggtgtctg |
2 |
CUGCCCUG | m8a | (m7a->m8a) | -0.081 | 0.011 |
-0.03 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr10:g.79314975C>A | 9_93750 | CRC-8-Tumor | Colorectal adenocarcinoma | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-19a-3p |
atacTTTGCACcagaaagg |
9 |
UGUGCAAA | m7b | Created | no TS | 0.056 |
-1.7 |
|
| hsa-miR-19b-3p |
atacTTTGCACcagaaagg |
9 |
UGUGCAAA | m7b | Created | no TS | 0.056 |
-0.98 |
|
| hsa-miR-4299 |
atactttgCACCAGaaagg |
17 |
GCUGGUGA | m6b | Created | -0.06 | -0.072 |
-0.15 |
|
| hsa-miR-4456 |
atactttgCACCAGaaagg |
17 |
CCUGGUGG | m6b | Created | -0.234 | -0.226 | No effect | |
| hsa-miR-4667-5p |
atactttgCCCCAGaaagg |
17 |
ACUGGGGA | m6b | Disrupted | -0.028 | 0.009 |
0.39 |
|
| hsa-miR-4700-5p |
atactttgCCCCAGAaagg |
14 |
UCUGGGGA | m7a | Disrupted | -0.055 | -0.021 |
0.21 |
|
| hsa-miR-486-3p |
atacttTGCCCCagaaagg |
10 |
CGGGGCAG | m6b | Disrupted | -0.119 | -0.072 |
0.01 |
|
| hsa-miR-518a-5p |
ataCTTTGCAccagaaagg |
9 |
CUGCAAAG | m7b | (m6b->m7b) | no TS | 0.078 |
-0.07 |
|
| hsa-miR-527 |
ataCTTTGCAccagaaagg |
9 |
CUGCAAAG | m7b | (m6b->m7b) | no TS | 0.078 |
-0.07 |
|
| hsa-miR-548q |
atactttGCACCAGaaagg |
11 |
GCUGGUGC | m7b | Created | -0.702 | -0.883 |
-0.38 |
|
| hsa-miR-637 |
atactttgCCCCAGaaagg |
17 |
ACUGGGGG | m6b | Disrupted | -0.312 | -0.284 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr10:g.79315677C>T | COSN5291188 | RK316_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1275 |
cctgaTCCCCCAgagagct |
0 | GUGGGGGA | m7b | Disrupted | -0.129000 | no TS |
0.060000 |
|
| hsa-miR-146a-3p |
cctgatcccTCAGAGagct |
0 | CCUCUGAA | m6b | Created | no TS | 0.015000 |
-0.070000 |
|
| hsa-miR-301a-5p |
cctgatcccTCAGAGagct |
0 | GCUCUGAC | m6b | Created | no TS | 0.014000 |
-0.070000 |
|
| hsa-miR-3191-5p |
cctgatcccCCAGAGAGct |
0 | CUCUCUGG | m8a | (m8a->m7b) | -0.041000 | -0.059000 | No effect | |
| hsa-miR-326 |
cctgatccCCCAGAGagct |
0 | CCUCUGGG | m7b | Disrupted | -0.042000 | 0.068000 |
0.020000 |
|
| hsa-miR-330-5p |
cctgatccCCCAGAGAgct |
0 | UCUCUGGG | m8a | Disrupted | -0.042000 | 0.068000 | No effect | |
| hsa-miR-3921 |
cctgatccCTCAGAGAgct |
0 | UCUCUGAG | m8a | Created | no TS | -0.046000 |
1.020000 |
|
| hsa-miR-4314 |
cctgatccCCCAGAGagct |
9 |
CUCUGGGA | m7a | Disrupted | 0.078000 | 0.078000 |
0.010000 |
|
| hsa-miR-4525 |
cctgATCCCCCagagagct |
0 | GGGGGGAU | m7b | Disrupted | -0.191000 | no TS |
0.010000 |
|
| hsa-miR-4653-5p |
cctgatccCTCAGAGAgct |
0 | UCUCUGAG | m8a | Created | no TS | -0.078000 |
-2.460000 |
|
| hsa-miR-4665-5p |
cctgaTCCCCCAGagagct |
0 | CUGGGGGA | m8a | Disrupted | -0.101000 | no TS | No effect | |
| hsa-miR-4667-5p |
cctgatcCCCCAGagagct |
0 | ACUGGGGA | m6b | Disrupted | -0.028000 | 0.049000 |
0.010000 |
|
| hsa-miR-5010-5p |
cctgATCCCCCagagagct |
0 | AGGGGGAU | m7b | Disrupted | -0.180000 | no TS |
0.360000 |
|
| hsa-miR-625-5p |
cctgaTCCCCCagagagct |
0 | AGGGGGAA | m6b | Disrupted | -0.081000 | no TS |
0.160000 |
|
| hsa-miR-637 |
cctgatCCCCCAGagagct |
0 | ACUGGGGG | m7b | Disrupted | -0.312000 | -0.013000 |
0.190000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr10:g.79316208C>G | COSN8640528 | 1409_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-210 |
aagtaactCGCACAGaaac |
0 | CUGUGCGU | m7a | Created | NA | NA |
0.350000 |
| hsa-miR-4265 |
aagtaactCCCACAGaaac |
1 |
CUGUGGGC | m7a | Disrupted | -0.001000 | -0.001000 | No effect |
| hsa-miR-4322 |
aagtaactCCCACAGaaac |
1 |
CUGUGGGC | m7a | Disrupted | -0.001000 | -0.001000 |
0.010000 |
| hsa-miR-4653-3p |
aagTAACTCCcacagaaac |
5 |
UGGAGUUA | m7b | (m7b->m6b) | -0.194000 | -0.084000 |
0.860000 |
| hsa-miR-4769-5p |
aagtaacTCCCACagaaac |
5 |
GGUGGGAU | m6b | Disrupted | -0.161000 | no TS | No effect |
| hsa-miR-5008-3p |
aagtaactcGCACAGaaac |
0 | CCUGUGCU | m6b | Created | no TS | -0.131000 |
-0.080000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 79312847 | rs138798050 | A | G |
hsa-miR-4466 hsa-miR-4706 hsa-miR-4749-5p hsa-miR-548q hsa-miR-675-5p hsa-miR-744-5p |
1 1 1 1 1 1 |
cgccCCGCACCAg cgCCCCGCAccag cgCCCCGCAccag cgccccGCACCAG cgccCCGCACCAg cGCCCCGCAccag |
Created Created Created Created Created Created |
N N N N N N |
-0.471 -0.218 -0.225 -0.2 -0.429 -0.496 |
| A |
hsa-miR-3151-5p hsa-miR-3180 hsa-miR-3180-3p hsa-miR-3196 hsa-miR-3650 hsa-miR-4447 hsa-miR-4472 hsa-miR-491-5p hsa-miR-6742-5p hsa-miR-6796-5p hsa-miR-6816-5p hsa-miR-7978 |
1 1 1 1 1 1 1 1 1 1 1 1 |
cGCCCCACAccag CGCCCCAcaccag CGCCCCAcaccag CGCCCCAcaccag cgcccCACACCAg cgCCCCACAccag cgCCCCACAccag cgCCCCACAccag cgCCCCACAccag cgCCCCACAccag CGCCCCAcaccag cgccccACACCAG |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N N N N N |
-0.366 -0.273 -0.274 -0.278 -0.08 -0.117 -0.117 -0.116 -0.125 -0.126 -0.275 -0.15 |
|||
| 79312934 | rs201108326 | - | CCAGG |
hsa-miR-1343-3p hsa-miR-548q hsa-miR-6783-3p |
1 0 1 |
caccagtgcaCCAGGAAggct caccagtGCACCAGgaaggct caccagtgcaCCAGGAAggct |
Unknown Unknown Unknown |
N N N |
-0.075 -0.173 -0.062 |
| - |
hsa-miR-3121-5p hsa-miR-4325 hsa-miR-507 hsa-miR-557 hsa-miR-7703 |
0 |
caccagtGCAAAGGct caccAGTGCAAaggct caccaGTGCAAAggct caccaGTGCAAAggct caccAGTGCAAaggct |
Unknown Unknown Unknown Unknown Unknown |
N N N N N |
-0.1 -0.087 -0.047 -0.057 -0.086 |
|||
| 79313620 | rs180937029 | A | A |
hsa-miR-103a-2-5p hsa-miR-3977 hsa-miR-4256 hsa-miR-6885-3p |
0 |
gtcAGAAGCAaac gtcaGAAGCAAac GTCAGAAgcaaac gtcagAAGCAAAc |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.019 -0.007 -0.005 0.103 |
| G |
hsa-miR-2682-3p hsa-miR-301a-5p hsa-miR-3152-5p hsa-miR-4774-3p hsa-miR-6781-3p hsa-miR-6836-3p |
0 |
gtcAGAGGCAaac GTCAGAGgcaaac gtcaGAGGCAAAc gtcagAGGCAAAc gtcAGAGGCAaac gtcaGAGGCAAac |
Created Created Created Created Created Created |
N N N N N N |
-0.071 -0.054 -0.144 -0.026 -0.071 -0.053 |
|||
| 79313859 | rs114939330 | C | C |
hsa-miR-106b-3p hsa-miR-18a-3p hsa-miR-6886-3p hsa-miR-6890-3p hsa-miR-938 |
1 2 2 2 2 |
caagggCAGTGCG caAGGGCAGtgcg cAAGGGCAgtgcg caagGGCAGTGcg cAAGGGCAgtgcg |
Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N |
-0.094 -0.047 -0.024 -0.02 -0.04 |
| T |
hsa-miR-4999-3p |
2 |
caagGGTAGTGcg |
Created |
N |
-0.011 |
|||
| 79313955 | rs41306560 | C | |||||||
| A |
hsa-miR-486-3p hsa-miR-661 hsa-miR-6852-5p |
8 8 8 |
TGCCCCAggctgc tgcCCCAGGCtgc tgCCCCAGGctgc |
Created Created Created |
N N N |
-0.099 -0.03 -0.002 |
|||
| 79314041 | rs55865960 | G | G |
hsa-miR-1231 hsa-miR-4667-5p hsa-miR-4700-5p hsa-miR-637 hsa-miR-6733-3p hsa-miR-7155-5p hsa-miR-8089 |
2 2 2 2 2 2 2 |
gccCCAGACActg gCCCCAGAcactg gCCCCAGAcactg gCCCCAGAcactg gccccaGACACTG gCCCCAGAcactg gCCCCAGAcactg |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N |
0.086 0.006 0.006 0.015 0.091 -0.008 0.009 |
| A |
hsa-miR-1227-5p hsa-miR-4260 hsa-miR-450a-2-3p hsa-miR-5572 hsa-miR-6740-5p |
2 2 2 2 2 |
GCCCCAAacactg GCCCCAAAcactg gCCCCAAAcactg gCCCCAAAcactg gcCCCAAACActg |
Created Created Created Created Created |
N N N N N |
-0.031 -0.06 0.034 0.022 0.076 |