SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_014870
Gene Symbol: ZBTB40
Description: Homo sapiens zinc finger and BTB domain containing 40 (ZBTB40), transcript variant 1, mRNA.
Gene Location: chr1(+):22778343-22857650
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr1:g.22526516C>T COSN1099292 HCC41T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3152-3p agcaccaaCTAACACAgtc
0 UGUGUUAG m8a Created no TS -0.306000 -1.010000
hsa-miR-4259 agcaCCAACTaacacagtc
2
CAGUUGGG m6b Created -0.257000 -0.372000 No effect
hsa-miR-4715-5p agcaCCAACTaacacagtc
0 AAGUUGGC m6b Created no TS -0.134000 -1.100000
hsa-miR-92a-1-5p agcaCCAACCaacacagtc
5
AGGUUGGG m6b Disrupted -0.142000 no TS 0.020000
hsa-miR-3152-3p agcaccaaCTAACACAgtc
0 UGUGUUAG m8a Created no TS -0.306 -1.01
hsa-miR-4259 agcaCCAACTaacacagtc
0 CAGUUGGG m6b Created -0.257 -0.372 No effect
hsa-miR-4715-5p agcaCCAACTaacacagtc
0 AAGUUGGC m6b Created no TS -0.134 -1.1
hsa-miR-92a-1-5p agcaCCAACCaacacagtc
5
AGGUUGGG m6b Disrupted -0.142 no TS 0.02


Mutation Mutation ID Sample Name Cancer Type
chr1:g.22526533G>T COSN15422583 AOCS-139-19-0 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr1:g.22526648G>A COSN6446204 CHC205T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1184 cgctGCTGCAGcctctatg
0 CCUGCAGC m7b Created no TS -0.108000 0.040000
hsa-miR-3188 cgctgctgcAGCCTCTatg
0 AGAGGCUU m7a (m6b->m7a) NA NA 0.210000
hsa-miR-485-5p cgctgctgCAGCCTCTatg
0 AGAGGCUG m8a Created -0.039000 -0.151000 0.020000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.22527060A>C COSN15613457 C0046T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2052 tccCAAAACAaagctctgg
2
UGUUUUGA m7a (m7a->m6a) 0.107000 0.070000 0.140000
hsa-miR-29b-2-5p tcccaAAACCAagctctgg
0 CUGGUUUC m6b Created no TS 0.042000 No effect
hsa-miR-4453 tcccaaaaCCAAGCTCtgg
0 GAGCUUGG m8a Created no TS -0.140000 -5.450000
hsa-miR-4538 tcccaaaaCCAAGCTCtgg
0 GAGCUUGG m8a Created no TS -0.159000 -5.420000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.22527151T>C COSN8436943 AOCS-169-1-0 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3927 tggtattccCTACCTGaag
0 CAGGUAGA m7a (m6b->m7a) NA NA -0.290000
hsa-miR-5584-5p tggtaTTCCCTacctgaag
0 CAGGGAAA m6b Created 0.150000 0.117000 -0.030000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.22528406G>A COSN6025918 RK183_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-129-1-3p attgctgAGGGCTTatagg
0 AAGCCCUU m7a Disrupted 0.005000 0.005000 1.510000
hsa-miR-129-2-3p attgctgAGGGCTTatagg
0 AAGCCCUU m7a Disrupted 0.005000 0.005000 1.960000
hsa-miR-4687-5p attgctGAGGGCTtatagg
2
CAGCCCUC m7b Disrupted -0.293000 -0.154000 1.720000
hsa-miR-99a-3p attgctgaGAGCTTatagg
0 CAAGCUCG m6b Created no TS -0.034000 -0.470000
hsa-miR-99b-3p attgctgaGAGCTTatagg
0 CAAGCUCG m6b Created no TS -0.024000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr1:g.22528462C>T COSN5367037 RK169_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4671-5p aaaacTCTTCGGaataaag
0 ACCGAAGA m7b Disrupted -0.332000 -0.172000 0.150000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.22528804A>G ICGC_92B7352C-2A78-11E2-8335-12FD496BB9B8 CPCG_0102_Pr_P_P2 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4530 caaagTGCTGGGattacag
0 CCCAGCAG m7a Created -0.418 -0.418 No effect
hsa-miR-4733-5p caaagtgcTGGGATTacag
0 AAUCCCAA m7a Created NA NA -0.01

Mutation Mutation ID Sample Name Cancer Type
chr1:g.22529225A>G COSN9025251 8057646 [pancreas][NS][carcinoid-endocrine_tumour][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4491 tgagTCCACATcgctcgct
4
AAUGUGGA m7b Disrupted 0.133000 0.039000 -0.250000
hsa-miR-4657 tgagTCCACATcgctcgct
4
AAUGUGGA m7b Disrupted 0.170000 0.048000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr1:g.22530108T>C COSN6446209 CHC205T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-let-7a-2-3p aaccaTGTACAGagtgggc
0 CUGUACAG m7a Created NA NA -0.350000
hsa-let-7a-3p aaccaTGTATAGagtgggc
0 CUAUACAA m7a Disrupted 0.018000 0.018000 0.010000
hsa-let-7b-3p aaccaTGTATAGagtgggc
0 CUAUACAA m7a Disrupted 0.021000 0.021000 0.660000
hsa-let-7f-1-3p aaccaTGTATAGagtgggc
0 CUAUACAA m7a Disrupted 0.021000 0.021000 0.050000
hsa-let-7f-2-3p aaccaTGTATAGagtgggc
0 CUAUACAG m7a Disrupted -0.101000 -0.101000 0.010000
hsa-let-7g-3p aaccaTGTACAGagtgggc
0 CUGUACAG m7a Created NA NA No effect
hsa-miR-1284 aaccaTGTATAGAgtgggc
1
UCUAUACA m8a Disrupted 0.037000 no TS 0.040000
hsa-miR-3664-5p aaccatgtACAGAGTgggc
0 AACUCUGU m7b Created no TS 0.036000 No effect
hsa-miR-4666a-5p aacCATGTATagagtgggc
0 AUACAUGU m7a (m7a->m6a) NA NA No effect
hsa-miR-493-5p aaccATGTACAgagtgggc
0 UUGUACAU m7b Created 0.144000 0.235000 -0.160000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.22530465C>A COSN7207021 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-186-3p ctgtctgtaCTTTGGGgac
6
GCCCAAAG m7b (m7b->m6c) 0.163000 0.233000 0.050000
hsa-miR-3973 ctgtctgTACTTTGgggac
8
ACAAAGUA m7b Disrupted 0.007000 -0.050000 0.230000
hsa-miR-548av-5p ctgtctGTACTTTggggac
9
AAAAGUAC m7b Disrupted -0.143000 -0.174000 0.080000
hsa-miR-548k ctgtctGTACTTTggggac
9
AAAAGUAC m7b Disrupted -0.143000 -0.174000 0.010000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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