SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_016653
Gene Symbol: ZAK
Description: Homo sapiens sterile alpha motif and leucine zipper containing kinase AZK (ZAK), transcript variant 1, mRNA.
Gene Location: chr2(+):173940564-174132737
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr2:g.173266784->A ICGC_ssm_v3_3457 BN06T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr2:g.173266784A>- ICGC_ssm_v3_76947 HCC139T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr2:g.173266810T>C COSN1228887 HCC88T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1537 gaaatgtaACGGTTTTtga
 0 AAAACCGU m8a Created no TS -0.343000 -2.120000
hsa-miR-451a gaaatgtAACGGTTTttga
 0 AAACCGUU m8a Created no TS -0.369000 -2.120000
hsa-miR-548aa gaaatgtaaTGGTTTTTga
 2
 AAAAACCA m8a (m8a->m7b) -0.214000 no TS 0.170000
hsa-miR-548ap-3p gaaatgtaaTGGTTTTTga
 2
 AAAAACCA m8a (m8a->m7b) -0.214000 no TS 0.480000
hsa-miR-548at-3p gaaatgtaaCGGTTTTtga
 0 CAAAACCG m7b (m6c->m7b) no TS -0.266000 -0.700000
hsa-miR-548t-3p gaaatgtaaTGGTTTTTga
 2
 AAAAACCA m8a (m8a->m7b) -0.214000 no TS 0.170000
hsa-miR-885-5p gaaatGTAATGGtttttga
 7
 UCCAUUAC m7b Disrupted -0.293000 no TS 3.980000
hsa-miR-1537 gaaatgtaACGGTTTTtga
 0 AAAACCGU m8a Created no TS -0.343 -2.12
hsa-miR-451a gaaatgtAACGGTTTttga
 0 AAACCGUU m8a Created no TS -0.369 -2.12
hsa-miR-548aa gaaatgtaaTGGTTTTTga
 0 AAAAACCA m8a (m8a->m7b) -0.214 no TS 0.17
hsa-miR-548ap-3p gaaatgtaaTGGTTTTTga
 0 AAAAACCA m8a (m8a->m7b) -0.214 no TS 0.48
hsa-miR-548at-3p gaaatgtaaCGGTTTTtga
 0 CAAAACCG m7b (m6c->m7b) no TS -0.266 -0.7
hsa-miR-548t-3p gaaatgtaaTGGTTTTTga
 0 AAAAACCA m8a (m8a->m7b) -0.214 no TS 0.17
hsa-miR-885-5p gaaatGTAATGGtttttga
 7
 UCCAUUAC m7b Disrupted -0.293 no TS 3.98

Mutation Mutation ID Sample Name Cancer Type
chr2:g.173267444T>G COSN7117137 8015127 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4719 gtaagatATTTGTGtctgt
 8
 UCACAAAU m7b Disrupted -0.118000 -0.043000 -0.850000
hsa-miR-4789-3p gtaagaTATGTGTGtctgt
 0 CACACAUA m8a Created no TS -0.075000 -3.630000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.173267474G>A COSN7117138 8014807 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4277 agttGAACTGatctggctt
 9
 GCAGUUCU m6b Disrupted -0.060000 no TS 8.420000
hsa-miR-5000-5p agtTGAACTGatctggctt
 8
 CAGUUCAG m7a (m7a->m6a) 0.000000 0.000000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.173267559C>A COSN9116751 AOCS-093-3-6 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3161 acgatTTATCAGaaaccaa
 0 CUGAUAAG m7a Disrupted NA NA No effect
hsa-miR-4762-3p acgatttATCAGAAaccaa
 9
 CUUCUGAU m7b Disrupted -0.241000 -0.060000 0.340000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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