SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_022459 |
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Gene Symbol: | XPO4 |
Description: | Homo sapiens exportin 4 (XPO4), mRNA. |
Gene Location: | chr13(-):21351467-21476913 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.20778369T>C | COSN8776346 | AOCS-116-1-3 | [ovary][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3662 |
gtTCATTTTCaacctgaat |
2 |
GAAAAUGA | m8a | (m7b->m8a) | 0.391000 | 0.418000 | No effect | |
hsa-miR-548c-3p |
gttcATTTTTaacctgaat |
4 |
CAAAAAUC | m6b | Disrupted | 2.286000 | 2.127000 |
0.080000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.20778393A>G | COSN5189800 | SS6003117 | [oesophagus][NS][carcinoma][adenocarcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4325 |
ttaaagaAAGTGCAtcttt |
12 |
UUGCACUU | m7b | Created | -0.217000 | -0.339000 |
-0.280000 |
|
hsa-miR-586 |
ttaaagaaAATGCATcttt |
2 |
UAUGCAUU | m7b | Disrupted | -0.081000 | 0.032000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.20778949T>C | COSN6223339 | RK214_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-374a-3p |
tcaggtTGATAAaatttta |
0 | CUUAUCAG | m6b | Disrupted | 0.074000 | no TS | No effect | |
hsa-miR-505-3p |
tcagGTTGACaaaatttta |
0 | CGUCAACA | m6b | Created | no TS | -0.024000 |
-0.120000 |
|
hsa-miR-590-3p |
tcaggttgaTAAAATTtta |
3 |
UAAUUUUA | m7b | (m7b->m6b) | 1.546000 | 1.381000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.20780321G>T | COSN6538637 | ICGC_MB69 | [central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3653 |
catcaTTCTTAaccctgaa |
2 |
CUAAGAAG | m6b | Created | 0.023000 | 0.157000 |
-0.010000 |
|
hsa-miR-3658 |
catcaTTCTTAAccctgaa |
2 |
UUUAAGAA | m7b | Created | 0.179000 | 0.330000 |
-0.020000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.20780980T>C | COSN6223340 | RK308_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4475 |
attttattTCCCTTGaccc |
0 | CAAGGGAC | m7a | Created | NA | NA |
-0.040000 |
|
hsa-miR-5584-5p |
attttaTTTCCCTtgaccc |
0 | CAGGGAAA | m7b | Created | no TS | -0.031000 |
-0.750000 |
|
hsa-miR-561-5p |
attttatttTCCTTGAccc |
2 |
AUCAAGGA | m7b | (m7b->m6b) | -0.050000 | no TS |
0.960000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.20781345T>C | COSN8776347 | AOCS-139-12-5 | [ovary][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4691-3p |
tcaggGTGGCTGtgtccat |
0 | CCAGCCAC | m7b | Created | -0.017000 | -0.026000 |
-0.890000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.20781891T>C | COSN7395154 | 8031146 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3148 |
tttttTTTTTCCccttaaa |
1 |
UGGAAAAA | m7b | Disrupted | 0.158000 | 0.177000 | No effect | |
hsa-miR-4668-5p |
ttttttTTTTCCCcttaaa |
3 |
AGGGAAAA | m7b | Disrupted | 0.076000 | 0.115000 |
0.010000 |
|
hsa-miR-4716-3p |
ttttttttTCCCCCTTaaa |
0 | AAGGGGGA | m8a | Created | no TS | -0.242000 |
-0.020000 |
|
hsa-miR-625-5p |
tttttttTTCCCCCTtaaa |
5 |
AGGGGGAA | m8a | Created | -0.121000 | -0.262000 |
-0.010000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.20782736A>G | COSN6223341 | RK200_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-103b |
ttagctGCTATGAacctgt |
11 |
UCAUAGCC | m7a | Disrupted | -0.280000 | -0.246000 |
0.260000 |
|
hsa-miR-3120-3p |
ttagcTGCTGTGaacctgt |
2 |
CACAGCAA | m7a | Created | 0.037000 | 0.037000 | No effect | |
hsa-miR-376a-3p |
ttagctgCTATGAacctgt |
4 |
AUCAUAGA | m6b | Disrupted | 0.090000 | 0.060000 | No effect | |
hsa-miR-376b |
ttagctgCTATGAacctgt |
4 |
AUCAUAGA | m6b | Disrupted | 0.090000 | 0.060000 | No effect | |
hsa-miR-4524a-5p |
ttaGCTGCTATgaacctgt |
1 |
AUAGCAGC | m8a | Disrupted | -0.274000 | -0.128000 |
0.330000 |
|
hsa-miR-4524b-5p |
ttaGCTGCTATgaacctgt |
1 |
AUAGCAGC | m8a | Disrupted | -0.274000 | -0.128000 |
0.040000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr13:g.20782874T>C | 9_77158 | CRC-7-Tumor | Colorectal adenocarcinoma | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
20780094 | rs190606708 | A | A |
hsa-miR-103b hsa-miR-4662a-5p |
2 2 |
ttGGCTATGAggt TTGGCTAtgaggt |
Disrupted Disrupted |
N N |
-0.132 -0.038 |
C |
hsa-miR-6501-3p |
2 |
ttgGCTCTGAggt |
Created |
N |
-0.011 |
|||
20781891 | rs147997558 | - | T |
hsa-miR-3148 hsa-miR-4668-5p hsa-miR-6783-5p |
1 1 1 |
ttTTTTTCCcctt tttTTTTCCCctt tttttTTCCCCTt |
Unknown Unknown Unknown |
N N N |
-0.004 -0.013 0.008 |
- |