SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_016206
Gene Symbol: VGLL3
Description: Homo sapiens vestigial like 3 (Drosophila) (VGLL3), mRNA.
Gene Location: chr3(-):86987122-87040257
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr3:g.86938094A>G COSN6782711 RK183_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4659a-3p aacagaaatGAAGAAAaat
11
UUUCUUCU m7a (m6a->m7a) 0.076000 0.003000 -0.010000
hsa-miR-4659b-3p aacagaaatGAAGAAAaat
11
UUUCUUCU m7a (m6a->m7a) 0.076000 0.003000 No effect
hsa-miR-5696 aacagAAATGAagaaaaat
3
CUCAUUUA m6b Created 0.430000 0.413000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86938666C>G COSN5150336 PD3890a [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-383 gctgCTGATCaataaatga
7
AGAUCAGA m6b Disrupted -0.093000 no TS No effect
hsa-miR-4772-5p gctgCTGATCAataaatga
7
UGAUCAGG m7a Disrupted -0.094000 no TS 0.040000
hsa-miR-664-3p gctgctgATGAATAaatga
6
UAUUCAUU m7a Created 0.153000 0.197000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86938959T>C COSN5544632 RK155_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-570-3p tgaagtgTGTTTTCtctgg
9
CGAAAACA m7b Disrupted 0.357000 0.258000 No effect
hsa-miR-603 tgaAGTGTGTtttctctgg
0 CACACACU m7b (m7b->m6c) -0.053000 no TS 0.250000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86939201C>T COSN8929717 SS6003302 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4275 tcttGTAATTGagaaggac
5
CCAAUUAC m7b Created 0.238000 0.328000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86939268T>C COSN8929718 SS6003317 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3691-3p gattagGACTTGGagccat
0 ACCAAGUC m7b Disrupted -0.096000 -0.053000 0.020000
hsa-miR-5695 gattaggaCTTGGAGccat
0 ACUCCAAG m7b Disrupted -0.208000 -0.165000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86939378T>C ICGC_72A824C6-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4530 cccaaagTGCTGGGattac
0 CCCAGCAG m7a Created -0.076 -0.076 -0.2
hsa-miR-4733-5p cccaaagtgTTGGGATTac
0 AAUCCCAA m8a (m8a->m7a) 0.052 no TS 0.76

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86939450A>G ICGC_D8AB4C62-2A78-11E2-B303-24FD496BB9B8 CPCG_0103_Pr_P_P6 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-605 agagacGGGATTTcaccat
0 UAAAUCCC m7b Disrupted 0.006 -0.079 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86939526C>T COSN14442081 8066037 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1827 cccCTGCCTCAgcctctcg
2
UGAGGCAG m8a Disrupted 0.026000 -0.038000 0.020000
hsa-miR-3714 cccCTGCCTTagcctctcg
1
GAAGGCAG m7b (m6c->m7b) 0.121000 0.242000 No effect
hsa-miR-3910 ccccTGCCTTagcctctcg
0 AAAGGCAU m6b Created no TS 0.084000 No effect
hsa-miR-3929 cccctgccTCAGCCTCtcg
8
GAGGCUGA m8a Disrupted 0.123000 0.018000 0.030000
hsa-miR-3975 cccctgcctTAGCCTCtcg
0 UGAGGCUA m7b (m6b->m7b) no TS 0.031000 -0.770000
hsa-miR-4419b cccctgccTCAGCCTCtcg
8
GAGGCUGA m8a Disrupted 0.105000 0.000000 0.020000
hsa-miR-4478 cccctgccTCAGCCTCtcg
8
GAGGCUGA m8a Disrupted 0.104000 0.018000 0.040000
hsa-miR-4649-3p cccctGCCTCAGcctctcg
2
UCUGAGGC m7b Disrupted 0.048000 no TS 0.070000
hsa-miR-485-5p cccctgcctCAGCCTCTcg
2
AGAGGCUG m8a (m8a->m7a) 0.038000 no TS 0.170000
hsa-miR-940 ccCCTGCCTTagcctctcg
1
AAGGCAGG m8a (m7b->m8a) 0.106000 0.079000 -0.390000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86939565C>G ICGC_C02CE11E-2A78-11E2-BDED-1EFD496BB9B8 CPCG_0103_Pr_P_P4 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-122-5p cggctCACTCCAacctcca
0 UGGAGUGU m7a Disrupted -0.067 -0.125 No effect
hsa-miR-3198 cggctcACTCCAacctcca
0 GUGGAGUC m6b Disrupted 0.064 no TS 2.15
hsa-miR-4309 cggctcACTCCAacctcca
0 CUGGAGUC m6b Disrupted 0.064 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86939921A>T COSN15284431 SM-4B295 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4728-3p catTCAGCATagatcttag
2
CAUGCUGA m7b (m6c->m7b) -0.365000 -0.370000 No effect
hsa-miR-628-5p catTCAGCATagatcttag
1
AUGCUGAC m7a (m6b->m7a) -0.180000 -0.184000 -0.020000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86939989T>A COSN15372044 0091_CRUK_PC_0091_T1_DNA [prostate][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2054 ctacATTACAacaacgata
2
CUGUAAUA m6b Created 0.331000 0.424000 0.010000
hsa-miR-3613-5p ctacatTACAACAacgata
2
UGUUGUAC m7a Created 0.013000 0.039000 -0.040000


Mutation Mutation ID Sample Name Cancer Type
chr3:g.86940041T>C COSN5048743 HX21T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr3:g.86940229A>G COSN7715165 8034061 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-130b-5p attgaAAAGAGaattccaa
4
ACUCUUUC m6b Disrupted 0.236000 0.152000 No effect
hsa-miR-204-5p attgaAAAGGGAAttccaa
6
UUCCCUUU m8a Created 0.026000 0.044000 -0.010000
hsa-miR-211-5p attgaAAAGGGAAttccaa
6
UUCCCUUU m8a Created 0.047000 0.065000 -0.010000
hsa-miR-3938 attgaaaAGGGAATTccaa
0 AAUUCCCU m8a Created no TS -0.034000 -0.190000
hsa-miR-4753-3p attgaAAAGAGAAttccaa
4
UUCUCUUU m8a Disrupted 0.450000 0.325000 No effect
hsa-miR-4755-5p attgaaAAGGGAAttccaa
7
UUUCCCUU m7b Created 0.151000 0.150000 No effect
hsa-miR-5006-3p attgaaAAGGGAAttccaa
7
UUUCCCUU m7b Created 0.154000 0.153000 No effect
hsa-miR-5571-5p attgaaaaGAGAATTccaa
0 CAAUUCUC m7b Disrupted 0.143000 0.044000 No effect
hsa-miR-623 attgaaAAGGGAattccaa
7
AUCCCUUG m6b Created 0.036000 0.041000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86940354G>A COSN5544633 RK101_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-548ao-5p taatacaaTACTTCTaagg
0 AGAAGUAA m7a Created NA NA -0.080000
hsa-miR-548ax taatacaaTACTTCTaagg
0 AGAAGUAA m7a Created NA NA No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86941104T>C COSN5150337 PD3945a [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3657 gaagatGGACACAatttgt
0 UGUGUCCC m7a Created no TS -0.064000 No effect
hsa-miR-3713 gaagatGGATACaatttgt
2
GGUAUCCG m6b Disrupted -0.058000 no TS 0.120000
hsa-miR-4669 gaagatGGACACAatttgt
0 UGUGUCCG m7a Created no TS -0.062000 -0.550000
hsa-miR-599 gaagatgGACACAAtttgt
4
GUUGUGUC m7b Created 0.043000 0.032000 -0.060000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86941781G>T COSN1969766 RK046_C02 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-300 aatCTTGTATtgctctctg
0 UAUACAAG m7b (m6c->m7b) 0.234000 0.304000 -0.010000
hsa-miR-381 aatCTTGTATtgctctctg
0 UAUACAAG m7b (m6c->m7b) 0.234000 0.295000 -0.010000
hsa-miR-3942-5p aatcttgTATTGCTctctg
2
AAGCAAUA m7b Created -0.079000 0.012000 -3.020000
hsa-miR-4703-5p aatcttgTATTGCTctctg
2
UAGCAAUA m7b Created -0.060000 -0.006000 -0.210000
hsa-miR-300 aatCTTGTATtgctctctg
0 UAUACAAG m7b (m6c->m7b) 0.234 0.304 -0.01
hsa-miR-381 aatCTTGTATtgctctctg
0 UAUACAAG m7b (m6c->m7b) 0.234 0.295 -0.01
hsa-miR-3942-5p aatcttgTATTGCTctctg
0 AAGCAAUA m7b Created -0.079 0.012 -3.02
hsa-miR-4703-5p aatcttgTATTGCTctctg
0 UAGCAAUA m7b Created -0.06 -0.006 -0.21

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86942603A>G COSN5544634 RK131_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-606 tcattcaccGTAGTTTata
2
AAACUACU m7a (m6a->m7a) 0.002000 0.002000 -0.010000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86942755T>C COSN8368946 tumor_4166706 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3653 gtacgtTTCTTAattagct
0 CUAAGAAG m6b Disrupted 0.427000 0.295000 0.960000
hsa-miR-3658 gtacgtTTCTTAAttagct
8
UUUAAGAA m7b Disrupted 0.467000 0.377000 0.020000
hsa-miR-4261 gtacGTTTCCTaattagct
6
AGGAAACA m7a Created -0.240000 -0.240000 No effect
hsa-miR-4496 gtacGTTTCCTaattagct
5
GAGGAAAC m7b Created 0.157000 0.256000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86942777A>G COSN1282972 HX10T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-155-3p ctacctggTGTAGGAGata
1
CUCCUACA m8a Created -0.013000 -0.001000 No effect
hsa-miR-337-3p ctacctggTATAGGAGata
2
CUCCUAUA m8a Disrupted 0.188000 0.089000 -0.010000
hsa-miR-4733-3p ctaCCTGGTGtaggagata
0 CCACCAGG m7b (m6c->m7b) no TS -0.086000 -0.050000
hsa-miR-155-3p ctacctggTGTAGGAGata
0 CUCCUACA m8a Created -0.013 -0.001 No effect
hsa-miR-337-3p ctacctggTATAGGAGata
0 CUCCUAUA m8a Disrupted 0.188 0.089 -0.01
hsa-miR-4733-3p ctaCCTGGTGtaggagata
0 CCACCAGG m7b (m6c->m7b) no TS -0.086 -0.05

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86943011G>C ICGC_72A829B2-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1231 acacacaCAGACACacaca
0 GUGUCUGG m7a Disrupted -0.18 -0.18 0.01
hsa-miR-147a acacacacaCACACACaca
0 GUGUGUGG m7a (m6a->m7a) -0.789 -0.789 0.03
hsa-miR-4711-3p acacacacAGACACacaca
0 CGUGUCUU m6b Disrupted -0.005 -0.041 2.86
hsa-miR-632 acacacaCAGACACacaca
0 GUGUCUGC m7a Disrupted 0.022 0.022 2.19

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86943804C>T COSN6782712 RK183_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4764-3p catcgGGAGTTAAgaaaca
2
UUAACUCC m8a Created -0.096000 -0.052000 -0.140000


Mutation Mutation ID Sample Name Cancer Type
chr3:g.86943933G>A COSN9726878 C0004T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr3:g.86944169C>A COSN9726879 C0059T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr3:g.86944231G>T COSN7715166 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4789-3p caggaccTATGTGTttggg
9
CACACAUA m7b Created -0.171000 -0.046000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86944291A>T COSN15132844 PD3851a [breast][NS][carcinoma][ductal_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4434 caccactgTTCTCCagctt
0 AGGAGAAG m6b Created no TS 0.085000 No effect
hsa-miR-4516 caccactgTTCTCCagctt
0 GGGAGAAG m6b Created no TS 0.085000 No effect
hsa-miR-4531 caccactgTTCTCCAgctt
9
AUGGAGAA m7b Created -0.035000 0.084000 No effect
hsa-miR-4773 caccaCTGTTCTccagctt
0 CAGAACAG m7b Created no TS 0.115000 No effect
hsa-miR-5703 caccactgTTCTCCagctt
0 AGGAGAAG m6b Created no TS 0.088000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86944404G>T COSN15478654 AOCS-095-1-4 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-365a-3p attacctGGGCATTgtggg
2
UAAUGCCC m7b Disrupted -0.359000 -0.331000 0.050000
hsa-miR-365b-3p attacctGGGCATTgtggg
2
UAAUGCCC m7b Disrupted -0.359000 -0.331000 0.050000
hsa-miR-4726-3p attACCTGGGcattgtggg
2
ACCCAGGU m7b (m7b->m6c) -0.129000 -0.052000 -1.200000
hsa-miR-365a-3p attacctGGGCATTgtggg
2
UAAUGCCC m7b Disrupted -0.359000 -0.331000 0.050000
hsa-miR-365b-3p attacctGGGCATTgtggg
2
UAAUGCCC m7b Disrupted -0.359000 -0.331000 0.050000
hsa-miR-4726-3p attACCTGGGcattgtggg
2
ACCCAGGU m7b (m7b->m6c) -0.129000 -0.052000 -1.200000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86944417A>G COSN5544635 RK050_C [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-30a-3p aaatttCTGAAAaattacc
9
CUUUCAGU m6b Disrupted 0.367000 0.283000 No effect
hsa-miR-30d-3p aaatttCTGAAAaattacc
9
CUUUCAGU m6b Disrupted 0.367000 0.283000 0.010000
hsa-miR-30e-3p aaatttCTGAAAaattacc
9
CUUUCAGU m6b Disrupted 0.371000 0.283000 No effect
hsa-miR-3180-5p aaattTCTGGAAaattacc
1
CUUCCAGA m7b Created 0.058000 0.100000 -0.010000
hsa-miR-3942-3p aaattTCTGAAAaattacc
3
UUUCAGAU m7a Disrupted 0.135000 0.077000 0.010000
hsa-miR-520a-5p aaattTCTGGAaaattacc
1
CUCCAGAG m6b Created -0.136000 -0.135000 -0.020000
hsa-miR-525-5p aaattTCTGGAaaattacc
1
CUCCAGAG m6b Created -0.136000 -0.125000 -0.050000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86945060T>A COSN8929719 SS6003320 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4282 aggttAAATTTTctatact
2
UAAAAUUU m7b Disrupted 1.507000 1.294000 -0.040000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86945138T>C COSN1969767 RK004_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-128 tttttacCACTGTGgggtc
11
UCACAGUG m7b Created -0.011000 0.049000 -0.050000
hsa-miR-3681-3p tttttacCACTGTGgggtc
11
ACACAGUG m7b Created -0.029000 0.022000 -0.050000
hsa-miR-128 tttttacCACTGTGgggtc
0 UCACAGUG m7b Created -0.011 0.049 -0.05
hsa-miR-3681-3p tttttacCACTGTGgggtc
0 ACACAGUG m7b Created -0.029 0.022 -0.05

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86945349G>T cosmic_v64_1751963 ccRCC
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-548at-5p catatatgcTAACTTTTta
0 AAAAGUUA m8a (m7a->m8a) 0.293 0.443 -13.45

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86945464T>C COSN9576890 AOCS-080-1-9 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-548ae gagaAGTTTTTtagcttta
4
CAAAAACU m7b Disrupted 0.636000 0.537000 No effect
hsa-miR-548ah-3p gagaAGTTTTTtagcttta
4
CAAAAACU m7b Disrupted 0.672000 0.573000 No effect
hsa-miR-548aj-3p gagaAGTTTTTtagcttta
4
UAAAAACU m7b Disrupted 0.636000 0.537000 No effect
hsa-miR-548am-3p gagaAGTTTTTtagcttta
4
CAAAAACU m7b Disrupted 0.672000 0.573000 No effect
hsa-miR-548aq-3p gagaAGTTTTTtagcttta
4
CAAAAACU m7b Disrupted 0.636000 0.537000 No effect
hsa-miR-548x-3p gagaAGTTTTTtagcttta
4
UAAAAACU m7b Disrupted 0.636000 0.537000 No effect
hsa-miR-5582-3p gagAAGTTTTttagcttta
2
UAAAACUU m7b (m7b->m6c) 0.274000 0.136000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86945484T>G COSN8929720 SS6003320 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4637 gtaaaaaAGTTAGTgtatt
8
UACUAACU m7b Disrupted -0.043000 no TS 0.300000
hsa-miR-4999-3p gtaaaaaaGGTAGTGtatt
2
UCACUACC m7b Created -0.026000 -0.187000 -4.910000


Mutation Mutation ID Sample Name Cancer Type
chr3:g.86945635C>A COSN8929721 SS6003317 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr3:g.86945711T>A cosmic_v64_1751955 ccRCC
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr3:g.86945787T>C COSN8929722 SS6003121 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1297 tggcttTACTTGAtttaat
2
UUCAAGUA m7b Disrupted 0.015000 0.072000 0.010000
hsa-miR-26a-5p tggcttTACTTGAtttaat
2
UUCAAGUA m7b Disrupted -0.006000 0.060000 0.020000
hsa-miR-26b-5p tggcttTACTTGAtttaat
2
UUCAAGUA m7b Disrupted 0.003000 0.060000 No effect
hsa-miR-4465 tggcttTACTTGAtttaat
2
CUCAAGUA m7b Disrupted 0.025000 0.082000 0.010000
hsa-miR-551b-5p tggctttacTTGATTTaat
8
GAAAUCAA m7b (m7b->m6b) 0.411000 0.357000 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86945961C>A COSN15411904 AOCS-167-16-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3145-3p ttgaaggaaAAATATCTgg
2
AGAUAUUU m8a (m7a->m8a) 0.028000 0.093000 No effect
hsa-miR-4326 ttgaAGGAACAatatctgg
0 UGUUCCUC m7a Disrupted -0.005000 0.035000 0.030000
hsa-miR-3145-3p ttgaaggaaAAATATCTgg
2
AGAUAUUU m8a (m7a->m8a) 0.028000 0.093000 No effect
hsa-miR-4326 ttgaAGGAACAatatctgg
0 UGUUCCUC m7a Disrupted -0.005000 0.035000 0.030000
hsa-miR-3145-3p ttgaaggaaAAATATCTgg
2
AGAUAUUU m8a (m7a->m8a) 0.028000 0.093000 No effect
hsa-miR-4326 ttgaAGGAACAatatctgg
0 UGUUCCUC m7a Disrupted -0.005000 0.035000 0.030000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86946139C>T COSN1969768 RK004_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1193 ctagcCCATCCaaatttga
11
GGGAUGGU m6b Disrupted -0.105000 no TS No effect
hsa-miR-432-3p ctagcCCATCCAaatttga
10
CUGGAUGG m7b Disrupted -0.196000 no TS 0.080000
hsa-miR-4790-3p ctagcCCATTCAaatttga
1
UGAAUGGU m7a Created -0.118000 -0.175000 No effect
hsa-miR-5004-3p ctagcccATCCAAatttga
8
CUUGGAUU m6b Disrupted -0.099000 -0.092000 0.050000
hsa-miR-1193 ctagcCCATCCaaatttga
0 GGGAUGGU m6b Disrupted -0.105 no TS No effect
hsa-miR-432-3p ctagcCCATCCAaatttga
0 CUGGAUGG m7b Disrupted -0.196 no TS 0.08
hsa-miR-4790-3p ctagcCCATTCAaatttga
0 UGAAUGGU m7a Created -0.118 -0.175 No effect
hsa-miR-5004-3p ctagcccATCCAAatttga
0 CUUGGAUU m6b Disrupted -0.099 -0.092 0.05

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86946358A>T COSN9576892 AOCS-135-8-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4251 ttacattgaTTCTCAGtaa
18
CCUGAGAA m7b (m6b->m7b) -0.058000 -0.194000 -0.010000
hsa-miR-5186 ttacattgAATCTCagtaa
9
AGAGAUUG m6b Disrupted -0.059000 no TS No effect
hsa-miR-580 ttacattgATTCTCAgtaa
0 UUGAGAAU m7b Created no TS -0.076000 -0.070000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86946405A>C COSN4822244 tumor_4135350 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][Burkitt_lymphoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5707 tcttaCAAACGTagctata
0 ACGUUUGA m7a Created NA NA No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86946526C>A COSN1969769 RK023_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-148a-5p tttaaAGAACTTgctctca
20
AAAGUUCU m7b Disrupted -0.013000 0.093000 No effect
hsa-miR-5584-3p tttaAAGAACTtgctctca
22
UAGUUCUU m7b Disrupted -0.014000 0.081000 No effect
hsa-miR-148a-5p tttaaAGAACTTgctctca
0 AAAGUUCU m7b Disrupted -0.013 0.093 4.11
hsa-miR-5584-3p tttaAAGAACTtgctctca
0 UAGUUCUU m7b Disrupted -0.014 0.081 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86946604G>T COSN5544636 RK030_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1323 aaaaAGTTTTGtttagcat
2
UCAAAACU m7b Created 0.153000 0.017000 No effect
hsa-miR-495 aaaaagtTTTGTTTagcat
2
AAACAAAC m7a Created 0.137000 0.137000 No effect
hsa-miR-497-3p aaaaagttTGGTTTagcat
0 CAAACCAC m6b Disrupted 0.092000 0.134000 No effect
hsa-miR-548o-3p aaaaAGTTTTGtttagcat
2
CCAAAACU m7b Created 0.149000 0.023000 No effect
hsa-miR-5582-3p aaaAAGTTTTgtttagcat
2
UAAAACUU m7b (m6c->m7b) 0.274000 0.203000 -0.010000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.86946635G>T COSN6575780 ICGC_MB76 [central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-376c gcTCTATGTTcatctattt
8
AACAUAGA m8a (m7b->m8a) -0.163000 -0.190000 -0.070000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table

Location SNP ID Ancestral
Allele
Allele miR ID Conservation miRSite FuncClass Validation context+
score change
86938124 rs192121161 G
A hsa-miR-3145-3p
hsa-miR-580-5p
1
1
AATATCAttaagt
aatATCATTAagt
Created
Created
N
N
-0.095
-0.064
86938125 rs115182530 C C hsa-miR-3145-3p
2
AAATATCgttaag
Disrupted
N
-0.072
T hsa-miR-16-2-3p
hsa-miR-195-3p
hsa-miR-338-5p
1
1
2
aAATATTGttaag
aAATATTGttaag
aaATATTGTtaag
Created
Created
Created
N
N
N
-0.105
-0.096
-0.117
86938130 rs147262877 A A hsa-miR-3145-3p
hsa-miR-4446-5p
2
2
tgggaAAATATCg
tGGGAAAAtatcg
Disrupted
Disrupted
N
N
-0.072
-0.104
C hsa-miR-190a-5p
hsa-miR-190b
hsa-miR-642b-5p
2
2
2
tgggaACATATCg
tgggaACATATCg
tGGGAACAtatcg
Created
Created
Created
N
N
N
-0.149
-0.158
-0.177
86938567 rs14416 A A hsa-miR-4728-3p
hsa-miR-8075
0 aTCAGCATtgatc
ATCAGCAttgatc
Disrupted
Disrupted
N
N
-0.139
-0.111
T hsa-miR-320a
hsa-miR-320b
hsa-miR-320c
hsa-miR-320d
hsa-miR-330-3p
hsa-miR-4429
14
14
14
14
17
14
atCAGCTTTgatc
atCAGCTTTgatc
atCAGCTTTgatc
atCAGCTTTgatc
atcaGCTTTGAtc
atCAGCTTTgatc
Created
Created
Created
Created
Created
Created
N
N
N
N
N
N
-0.093
-0.093
-0.093
-0.093
-0.025
-0.093
86938666 rs76771757 C C hsa-miR-383-5p
hsa-miR-4772-5p
7
7
gCTGATCAataaa
gCTGATCAataaa
Disrupted
Disrupted
N
N
-0.093
-0.094
G hsa-miR-664a-3p
13
gctgATGAATAaa
Created
N
0.044
86938718 rs74615560 T T hsa-miR-1323
hsa-miR-548o-3p
8
8
catGTTTTGAtag
catGTTTTGAtag
Disrupted
Disrupted
N
N
0.012
0.008
C hsa-miR-2115-3p
hsa-miR-361-5p
hsa-miR-589-3p
9
11
8
catgTTCTGATAg
catgtTCTGATAg
caTGTTCTGAtag
Created
Created
Created
N
N
N
-0.107
-0.089
-0.181
86939071 rs191278188 A A hsa-miR-606
1
tcatGTAGTTAtt
Disrupted
N
-0.018
G hsa-miR-6776-3p
1
tcatGTGGTTAtt
Created
N
-0.051
86939201 rs116104226 T C hsa-miR-516a-5p
0 tgtaaTCGAGAAg
Created
N
-0.096
T hsa-miR-4275
hsa-miR-513c-5p
hsa-miR-514b-5p
0 tGTAATTGAgaag
tgtaaTTGAGAAg
tgtaaTTGAGAAg
Disrupted
Disrupted
Disrupted
N
N
N
0.09
0.049
0.046
86939961 rs143440980 A A hsa-miR-3606-3p
hsa-miR-5010-3p
hsa-miR-513a-3p
hsa-miR-513c-3p
hsa-miR-599
4
4
4
4
4
aacacAAATTTAt
aACACAAAtttat
aacacAAATTTAt
aacacAAATTTAt
aACACAAAtttat
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
0.206
0.025
0.203
0.203
0.043
86940210 rs2232711 T T hsa-miR-300
hsa-miR-381-3p
2
2
CTTGTATtctgaa
CTTGTATtctgaa
Disrupted
Disrupted
N
N
0.103
0.103
C hsa-miR-759
2
cttgtACTCTGAa
Created
N
0.035
86940216 rs144668674 - C hsa-miR-300
hsa-miR-381-3p
hsa-miR-624-3p
2
2
1
caagacCTTGTAT
caagacCTTGTAT
caagACCTTGTAt
Unknown
Unknown
Unknown
N
N
N
0.05
0.05
No Change
- hsa-miR-1264
hsa-miR-6882-5p
4
1
cAAGACTTgtat
caaGACTTGTAt
Unknown
Unknown
N
N
0.089
-0.011
86941116 rs193207763 A A hsa-miR-204-5p
hsa-miR-211-5p
hsa-miR-4755-5p
hsa-miR-5006-3p
hsa-miR-623
hsa-miR-6832-3p
6
6
7
7
7
6
atttAAAGGGAAg
atttAAAGGGAAg
atttaAAGGGAAg
atttaAAGGGAAg
atttaAAGGGAAg
atttAAAGGGAag
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
-0.035
-0.014
-0.026
-0.026
-0.008
0.016
G hsa-miR-3127-3p
hsa-miR-6756-3p
hsa-miR-6826-3p
6
6
7
atttAAGGGGAag
atttAAGGGGAag
atttaAGGGGAAg
Created
Created
Created
N
N
N
-0.045
-0.052
-0.056
86941262 rs78993102 G G hsa-miR-551b-5p
10
acaaTTGATTTAa
Disrupted
N
0.143
T hsa-miR-5692a
12
acaatTTATTTAa
Created
N
0.173
86941980 rs192031605 C
T hsa-miR-1250-3p
hsa-miR-153-5p
hsa-miR-181a-5p
hsa-miR-181b-5p
hsa-miR-181c-5p
hsa-miR-181d-5p
hsa-miR-4262
hsa-miR-5696
hsa-miR-579-3p
hsa-miR-664a-3p
hsa-miR-664b-3p
1
1
1
1
1
1
1
1
1
1
1
caAAAATGAatgt
cAAAAATGAatgt
caaaaaTGAATGT
caaaaaTGAATGT
caaaaaTGAATGT
caaaaaTGAATGT
caaaaaTGAATGT
caaAAATGAAtgt
caaAAATGAAtgt
caaaAATGAATgt
caaAAATGAAtgt
Created
Created
Created
Created
Created
Created
Created
Created
Created
Created
Created
N
N
N
N
N
N
N
N
N
N
N
0.164
0.22
0.002
0.002
0.011
-0.008
0.011
0.133
0.13
0.111
0.144
86941999 rs189704743 T T hsa-miR-488-3p
hsa-miR-548at-5p
hsa-miR-653-5p
1
0
2
ctaaCTTTCAAca
cTAACTTTcaaca
ctaactTTCAACA
Disrupted
Disrupted
Disrupted
N
N
N
0.082
0.137
0.027
G hsa-miR-4645-3p
0 ctaACTGTCAaca
Created
N
0.001
86942673 rs138843924 T T hsa-miR-4496
hsa-miR-548a-3p
hsa-miR-548ar-3p
hsa-miR-548az-3p
hsa-miR-548e-3p
hsa-miR-548f-3p
hsa-miR-8065
1
1
1
1
1
1
0
cagtTTTCCTAca
CAGTTTTcctaca
CAGTTTTcctaca
CAGTTTTcctaca
CAGTTTTcctaca
CAGTTTTcctaca
cagttTTCCTACA
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
N
0.092
0.08
0.099
0.099
0.099
0.089
-0.112
C hsa-miR-135b-3p
hsa-miR-4738-3p
hsa-miR-5584-5p
hsa-miR-6750-5p
hsa-miR-6822-5p
0 cagtttCCCTACA
CAGTTTCcctaca
cagTTTCCCTAca
cagtTTCCCTAca
cagtTTCCCTAca
Created
Created
Created
Created
Created
N
N
N
N
N
-0.107
0.016
0.069
0.016
0.006
86942721 rs13087378 A A hsa-miR-205-5p
hsa-miR-6868-3p
7
7
ttcTGAAGGAaaa
ttctGAAGGAAaa
Disrupted
Disrupted
N
N
-0.012
0.012
G hsa-miR-4446-5p
hsa-miR-4755-5p
hsa-miR-5006-3p
hsa-miR-642a-5p
7
8
8
7
ttctgAGGGAAAA
ttctgAGGGAAAa
ttctgAGGGAAAa
ttctGAGGGAAaa
Created
Created
Created
Created
N
N
N
N
0.052
-0.003
No Change
-0.063
86942734 rs9834197 G
G hsa-miR-425-5p
hsa-miR-603
hsa-miR-642a-3p
hsa-miR-642b-3p
0 tttagtGTGTCAT
tttAGTGTGTcat
tttagTGTGTCAt
tttagTGTGTCAt
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
-0.042
-0.022
-0.019
-0.019
86943011 rs201753357 C G hsa-miR-4711-3p
0 cacacAGACACAc
Created
N
0.036
C hsa-miR-6867-5p
0 CACACACAcacac
Disrupted
N
0.244
86943012 rs67714439 - CA hsa-miR-4711-3p
hsa-miR-6867-5p
0 cacacacAGACACAc
CACACACAgacacac
Unknown
Unknown
N
N
No Change
0.087
-
86943013 rs10609628 - AC hsa-miR-6867-5p
2
aCACACACAgacaca
Unknown
N
0.087
- hsa-miR-4711-3p
0 acacacAGACACA
Unknown
N
No Change
86943021 rs62257343 C C hsa-miR-6867-5p
1
CACACACAcacac
Disrupted
N
0.128
G hsa-miR-4711-3p
3
cacacAGACACAc
Created
N
0.038
86943248 rs139135645 A G hsa-miR-614
0 agtGGCGTTAagt
Created
N
-0.077
A hsa-miR-155-5p
hsa-miR-365a-3p
hsa-miR-365b-3p
hsa-miR-4252
0 agtgGCATTAAgt
agtGGCATTAagt
agtGGCATTAagt
AGTGGCAttaagt
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
0.091
0.035
0.035
-0.043
86943884 rs144669218 A A hsa-miR-3145-3p
2
ttctAAATATCtg
Disrupted
N
0.1
G hsa-miR-374c-3p
2
ttCTAAGTAtctg
Created
N
0.031
86943948 rs186163643 C C hsa-miR-122-5p
hsa-miR-504-3p
hsa-miR-6880-5p
3
3
3
acCACTCCAcctt
acCACTCCAcctt
accaCTCCACCtt
Disrupted
Disrupted
Disrupted
N
N
N
-0.025
-0.016
-0.083
G hsa-miR-143-5p
hsa-miR-18a-5p
hsa-miR-18b-5p
hsa-miR-4735-3p
hsa-miR-6499-3p
3
3
3
3
3
accACTGCACctt
accactGCACCTT
accactGCACCTT
accactGCACCTT
acCACTGCAcctt
Created
Created
Created
Created
Created
N
N
N
N
N
-0.004
-0.09
-0.09
-0.09
-0.012
86944885 rs188452008 C C hsa-miR-1827
3
tattTGCCTCAtc
Disrupted
N
0.012
A hsa-miR-3671
hsa-miR-5702
hsa-miR-937-5p
3
3
3
TATTTGActcatc
tattTGACTCAtc
tattTGACTCAtc
Created
Created
Created
N
N
N
0.163
0.017
-0.008
86945628 rs192560770 G G hsa-miR-1200
hsa-miR-4324
hsa-miR-544b
5
1
5
tCTCAGGAtctaa
TCTCAGGAtctaa
tCTCAGGAtctaa
Disrupted
Disrupted
Disrupted
N
N
N
-0.068
-0.067
-0.02
A hsa-miR-376a-5p
hsa-miR-4251
hsa-miR-4303
hsa-miR-4329
hsa-miR-4760-5p
hsa-miR-6761-5p
hsa-miR-8061
5
1
5
1
6
1
6
tctcaGAATCTAA
TCTCAGAatctaa
tCTCAGAAtctaa
TCTCAGAatctaa
tctcagAATCTAA
TCTCAGAatctaa
tctcagAATCTAA
Created
Created
Created
Created
Created
Created
Created
N
N
N
N
N
N
N
-0.036
-0.01
No Change
-0.016
0.05
-0.036
0.042
86945974 rs1436639 G G hsa-miR-105-5p
hsa-miR-365a-3p
hsa-miR-365b-3p
hsa-miR-6886-3p
hsa-miR-7853-5p
hsa-miR-938
2
0
0
0
2
0
tgaaggGCATTTG
tgaaGGGCATTtg
tgaaGGGCATTtg
tGAAGGGCAtttg
tgaaggGCATTTG
tgAAGGGCAtttg
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
-0.049
-0.15
-0.15
-0.231
-0.056
-0.108
T hsa-miR-6759-3p
0 tgAAGGTCAtttg
Created
N
-0.05
86946109 rs149885454 A A hsa-miR-410-3p
hsa-miR-568
2
4
gGTTATATAcaac
ggttaTATACAAc
Disrupted
Disrupted
N
N
0.076
0.041
G hsa-let-7a-2-3p
hsa-let-7c-3p
hsa-let-7g-3p
hsa-miR-3613-5p
hsa-miR-493-5p
4
4
4
4
4
ggttaTGTACAAc
ggttaTGTACAAc
ggttaTGTACAAc
ggttatGTACAAC
ggttATGTACAAc
Created
Created
Created
Created
Created
N
N
N
N
N
No Change
0.006
-0.004
-0.137
-0.07
86946371 rs189973672 G G hsa-miR-548ac
hsa-miR-548ae
hsa-miR-548ah-3p
hsa-miR-548aj-3p
hsa-miR-548am-3p
hsa-miR-548aq-3p
hsa-miR-548d-3p
hsa-miR-548h-3p
hsa-miR-548j-3p
hsa-miR-548x-3p
hsa-miR-548z
5
5
5
5
5
5
5
5
5
5
5
agtattGTTTTTA
agtattGTTTTTA
agtattGTTTTTA
agtattGTTTTTA
agtattGTTTTTA
agtattGTTTTTA
agtattGTTTTTA
agtattGTTTTTA
agtattGTTTTTA
agtattGTTTTTA
agtattGTTTTTA
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
N
N
N
N
N
0.074
0.077
0.077
0.077
0.077
0.077
0.08
0.074
0.07
0.077
0.074

Genome Browser