SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001080491
Gene Symbol: USP6NL
Description: Homo sapiens USP6 N-terminal like (USP6NL), transcript variant 2, mRNA.
Gene Location: chr10(-):11502508-11574274
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr10:g.11460606C>T COSN6961329 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-223-5p atatatATACACacaagca
 4
 CGUGUAUU m6b Disrupted -0.118000 -0.126000 -0.080000
hsa-miR-5011-5p ataTATATATAcacaagca
 5
 UAUAUAUA m8a Created -2.904000 -3.126000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.11460656T>A COSN8639063 3030_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-410 tgtagatttTTATATatat
 0 AAUAUAAC m6b Disrupted 0.010000 0.019000 -0.430000
hsa-miR-5011-5p tgtagattTATATATAtat
 5
 UAUAUAUA m8a Created -2.904000 -3.076000 0.010000
hsa-miR-548c-3p tgtaGATTTTTatatatat
 7
 CAAAAAUC m7b Disrupted 0.070000 0.217000 0.230000
hsa-miR-410 tgtagatttTTATATatat
 0 AAUAUAAC m6b Disrupted 0.010000 0.019000 -0.430000
hsa-miR-5011-5p tgtagattTATATATAtat
 5
 UAUAUAUA m8a Created -2.904000 -3.076000 0.010000
hsa-miR-548c-3p tgtaGATTTTTatatatat
 7
 CAAAAAUC m7b Disrupted 0.070000 0.217000 0.230000
hsa-miR-410 tgtagatttTTATATatat
 0 AAUAUAAC m6b Disrupted 0.01 0.019 -0.43
hsa-miR-5011-5p tgtagattTATATATAtat
 0 UAUAUAUA m8a Created -2.904 -3.076 0.01
hsa-miR-548c-3p tgtaGATTTTTatatatat
 0 CAAAAAUC m7b Disrupted 0.07 0.217 0.23

Mutation Mutation ID Sample Name Cancer Type
chr10:g.11461393C>T COSN1471848 RK089_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-18a-5p gctGCACCTTAtcaggcca
 0 UAAGGUGC m8a Created no TS -0.212000 -1.160000
hsa-miR-18b-5p gctGCACCTTAtcaggcca
 0 UAAGGUGC m8a Created no TS -0.212000 -0.990000
hsa-miR-3161 gctgcacCTTATCAGgcca
 2
 CUGAUAAG m8a Created 0.021000 0.071000 -0.080000
hsa-miR-4502 gctgcaccTCATCAGgcca
 1
 GCUGAUGA m7b Disrupted -0.014000 no TS 2.230000
hsa-miR-4735-3p gctGCACCTTatcaggcca
 0 AAAGGUGC m7b (m6c->m7b) no TS -0.233000 -3.510000
hsa-miR-18a-5p gctGCACCTTAtcaggcca
 0 UAAGGUGC m8a Created no TS -0.212 -1.16
hsa-miR-18b-5p gctGCACCTTAtcaggcca
 0 UAAGGUGC m8a Created no TS -0.212 -0.99
hsa-miR-3161 gctgcacCTTATCAGgcca
 0 CUGAUAAG m8a Created 0.021 0.071 -0.08
hsa-miR-4502 gctgcaccTCATCAGgcca
 0 GCUGAUGA m7b Disrupted -0.014 no TS 2.23
hsa-miR-4735-3p gctGCACCTTatcaggcca
 0 AAAGGUGC m7b (m6c->m7b) no TS -0.233 -3.51

Mutation Mutation ID Sample Name Cancer Type
chr10:g.11461797C>T COSN1471850 RK096_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1252 attcTCCTTCagctgttgc
 8
 AGAAGGAA m6b Disrupted -0.047000 no TS 0.670000
hsa-miR-3173-3p attCTCCTTTagctgttgc
 0 AAAGGAGG m7a (m6b->m7a) NA NA -0.310000
hsa-miR-4509 attctCCTTTAGctgttgc
 0 ACUAAAGG m7b Created no TS -0.108000 -0.020000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.11462024A>G COSN6475665 CHC205T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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