SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_025218
Gene Symbol: ULBP1
Description: Homo sapiens UL16 binding protein 1 (ULBP1), mRNA.
Gene Location: chr6(+):150285142-150294846
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr6:g.149972278T>C ICGC_sm200271 RK041_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-29a-5p ttcgaAAATCAGTgctgga
0 ACUGAUUU m8a Created no TS 0.037 -0.1
hsa-miR-4735-5p ttcgaAAATTAGtgctgga
0 CCUAAUUU m7b Disrupted 0.103 no TS 0.93
hsa-miR-4775 ttcgAAAATTAgtgctgga
0 UUAAUUUU m7b Disrupted 0.276 0.055 No effect

Mutation Mutation ID Sample Name Cancer Type
chr6:g.149972510G>A ICGC_7BB8761A-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3189-5p acaaATGGGGCctcattaa
0 UGCCCCAU m7b Disrupted -0.149 no TS No effect
hsa-miR-5008-5p acaaatgGGGCCTCAttaa
0 UGAGGCCC m8a Disrupted -0.292 no TS -2.65

Mutation Mutation ID Sample Name Cancer Type
chr6:g.149972514C>A ICGC_A15123EA-2A78-11E2-8335-12FD496BB9B8 CPCG_0102_Pr_P_P2 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5008-5p atgGGGCCTCAttaaacta
0 UGAGGCCC m8a Disrupted -0.292 no TS 1.02

Mutation Mutation ID Sample Name Cancer Type
chr6:g.149972540A>C ICGC_7BB87AE8-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4652-3p tctgcACAGAAaaagaaac
0 GUUCUGUU m6b Disrupted -0.033 -0.088 0.12


Mutation Mutation ID Sample Name Cancer Type
chr6:g.149972603C>G 9_45526 CRC-5-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr6:g.149972712T>C ICGC_C346153C-2A78-11E2-BDED-1EFD496BB9B8 CPCG_0103_Pr_P_P4 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1253 cagacaCTTCTCaaaagaa
0 AGAGAAGA m6b Created -0.073 -0.069 -0.04
hsa-miR-548t-5p cagaCACTTTTcaaaagaa
0 CAAAAGUG m7b Disrupted 0.035 no TS 0.27
hsa-miR-580 cagacacTTCTCAAaagaa
0 UUGAGAAU m7a Created -0.053 -0.048 No effect

Mutation Mutation ID Sample Name Cancer Type
chr6:g.149972799T>G ICGC_sm453233 RK126_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1915-5p aaactGCAAGGagttacca
0 ACCUUGCC m6b Created -0.085 -0.163 -1.29
hsa-miR-25-3p aaacTGCAATGagttacca
0 CAUUGCAC m7a Disrupted NA NA -0.16
hsa-miR-4317 aaactGCAATGagttacca
0 ACAUUGCC m6b Disrupted -0.137 -0.088 0.01
hsa-miR-4764-3p aaactgcaaGGAGTTAcca
0 UUAACUCC m7b (m6c->m7b) no TS -0.082 -6.14
hsa-miR-502-5p aaactGCAAGGAgttacca
0 AUCCUUGC m7b Created -0.171 -0.298 -1.15

Mutation Mutation ID Sample Name Cancer Type
chr6:g.149973333C>T 10_18690 6408 Breast cancer
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table

Location SNP ID Ancestral
Allele
Allele miR ID Conservation miRSite FuncClass Validation context+
score change
149972277 rs12661158 T T hsa-miR-4735-5p
hsa-miR-4775
hsa-miR-590-3p
2
2
2
cgaAAATTAGtgc
cgAAAATTAgtgc
cgAAAATTAgtgc
Disrupted
Disrupted
Disrupted
N
N
N
0.103
0.221
0.196
149972494 rs4388299 G G hsa-miR-4652-3p
hsa-miR-4743-3p
2
2
aaAACAGAAAttg
aaaACAGAAAttg
Disrupted
Disrupted
N
N
0.011
0.023
149972666 rs75643450 A A hsa-miR-4659a-3p
hsa-miR-4659b-3p
hsa-miR-4778-3p
hsa-miR-6875-3p
2
2
2
2
agcaAGAAGAAAa
agcaAGAAGAAAa
agcAAGAAGAaaa
agcaaGAAGAAAa
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
0.007
0.007
0.032
0.047
G hsa-miR-1915-5p
hsa-miR-4279
hsa-miR-502-5p
hsa-miR-629-3p
hsa-miR-6841-3p
2
2
2
2
2
aGCAAGGAgaaaa
agcaAGGAGAAaa
aGCAAGGAgaaaa
agcaaGGAGAAAa
aGCAAGGAgaaaa
Created
Created
Created
Created
Created
N
N
N
N
N
-0.08
-0.03
-0.136
-0.015
-0.083
149972708 rs141741582 A A hsa-miR-548az-5p
hsa-miR-548t-5p
2
2
acagaCACTTTTc
acagaCACTTTTc
Disrupted
Disrupted
N
N
0.035
0.035
149972795 rs146225839 G G hsa-miR-4317
hsa-miR-4328
hsa-miR-6516-5p
2
1
2
aaaactGCAATGA
AAAACTGcaatga
aaaACTGCAAtga
Disrupted
Disrupted
Disrupted
N
N
N
-0.049
0.038
-0.096
T hsa-miR-3616-5p
hsa-miR-4670-3p
hsa-miR-573
2
2
2
aaaACTTCAAtga
aaAACTTCAatga
aaaACTTCAAtga
Created
Created
Created
N
N
N
-0.017
-0.001
-0.017
149973412 rs116605216 C C hsa-miR-1253
hsa-miR-6770-5p
hsa-miR-7160-5p
2
2
2
cctcagCTTCTCA
cctcagCTTCTCA
CCTCAGCttctca
Disrupted
Disrupted
Disrupted
N
N
N
-0.073
-0.088
-0.173
T hsa-miR-4738-3p
hsa-miR-539-5p
2
2
cctCAGTTTCtca
cctcagTTTCTCA
Created
Created
N
N
-0.1
-0.054
149973688 rs12110324 A C hsa-miR-135b-3p
0 aCCCTACAAttaa
Created
N
-0.551
A hsa-miR-2909
hsa-miR-4775
hsa-miR-590-3p
0 aCCCTAAAattaa
accctAAAATTAA
acccTAAAATTAa
Disrupted
Disrupted
Disrupted
N
N
N
-0.195
-0.054
0.028

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