SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_183415
Gene Symbol: UBE3B
Description: Homo sapiens ubiquitin protein ligase E3B (UBE3B), transcript variant 1, mRNA.
Gene Location: chr12(+):109915438-109974507
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr12:g.109535311A>T COSN15356577 AOCS-034-3-8 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1231 tcttcCCAGACAgccaggc
 3
 GUGUCUGG m7b Disrupted -0.042000 no TS 0.220000
hsa-miR-3120-5p tcttccCAGACAGccaggc
 2
 CCUGUCUG m7b Disrupted -0.010000 no TS No effect
hsa-miR-4314 tctTCCCAGAcagccaggc
 2
 CUCUGGGA m7b (m7b->m6b) -0.166000 -0.094000 0.010000
hsa-miR-4646-5p tcTTCCCAGTcagccaggc
 2
 ACUGGGAA m8a (m7a->m8a) -0.239000 -0.145000 0.390000
hsa-miR-626 tcttcccAGACAGCcaggc
 2
 AGCUGUCU m7b Disrupted -0.165000 -0.144000 No effect
hsa-miR-1231 tcttcCCAGACAgccaggc
 3
 GUGUCUGG m7b Disrupted -0.042000 no TS 0.220000
hsa-miR-3120-5p tcttccCAGACAGccaggc
 2
 CCUGUCUG m7b Disrupted -0.010000 no TS No effect
hsa-miR-4314 tctTCCCAGAcagccaggc
 2
 CUCUGGGA m7b (m7b->m6b) -0.166000 -0.094000 0.010000
hsa-miR-4646-5p tcTTCCCAGTcagccaggc
 2
 ACUGGGAA m8a (m7a->m8a) -0.239000 -0.145000 0.390000
hsa-miR-626 tcttcccAGACAGCcaggc
 2
 AGCUGUCU m7b Disrupted -0.165000 -0.144000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr12:g.109535343C>A COSN10097412 C0089T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1539 agggaaGCGCAGGcgcctg
 2
 UCCUGCGC m7b Disrupted -0.207000 no TS 8.330000
hsa-miR-191-3p agggaAGCGCAGgcgcctg
 1
 GCUGCGCU m7b Disrupted -0.115000 no TS No effect
hsa-miR-4790-5p agggAAGCGAaggcgcctg
 0 AUCGCUUU m6b Created no TS -0.071000 -0.020000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.109535416C>T COSN5930002 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3622b-5p cgcgctCCATGCCgcggcc
 2
 AGGCAUGG m7b Created -0.277000 -0.316000 No effect
hsa-miR-4304 cgcgctcCATGCCGcggcc
 2
 CCGGCAUG m7b Created -0.190000 -0.295000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr12:g.109536322G>A COSN8694264 AOCS-138-3-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4643 cttctgaaCATGTGTgcgc
 0 GACACAUG m7b Created no TS -0.079000 -0.690000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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