| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_015294 |
|---|---|
| Gene Symbol: | TRIM37 |
| Description: | Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant 2, mRNA. |
| Gene Location: | chr17(-):57075560-57184266 |
| Browse Associations | |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr17:g.58998328G>C | COSN9671640 | C0067T | [kidney][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1245b-3p |
atcTCATCTGctgtatttt |
5 |
UCAGAUGA | m7b | (m7b->m6c) | -0.145000 | no TS | No effect | |
| hsa-miR-143-3p |
atcTCATCTCctgtatttt |
3 |
UGAGAUGA | m7b | (m6c->m7b) | -0.117000 | -0.293000 | No effect | |
| hsa-miR-214-3p |
atctcatCTGCTGTatttt |
0 | ACAGCAGG | m7a | Disrupted | NA | NA |
-0.130000 |
|
| hsa-miR-3120-3p |
atctcatcTGCTGTatttt |
0 | CACAGCAA | m6b | Disrupted | -0.490000 | -0.328000 |
0.110000 |
|
| hsa-miR-4433-3p |
atctcatCTCCTGTatttt |
0 | ACAGGAGU | m7a | Created | NA | NA |
-0.480000 |
|
| hsa-miR-4700-3p |
atctcatcTCCTGTatttt |
0 | CACAGGAC | m6b | Created | no TS | -0.174000 |
-0.170000 |
|
| hsa-miR-4768-3p |
atctcaTCTCCTGtatttt |
0 | CCAGGAGA | m7b | Created | no TS | -0.276000 |
-0.210000 |
|
| hsa-miR-4770 |
atcTCATCTCctgtatttt |
3 |
UGAGAUGA | m7b | (m6c->m7b) | -0.110000 | -0.286000 | No effect | |
| hsa-miR-922 |
atctcaTCTGCTGtatttt |
2 |
GCAGCAGA | m7b | Disrupted | -0.259000 | no TS | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr17:g.58998494T>A | COSN9671641 | C0013T | [kidney][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-548a-5p |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.136000 | -0.170000 |
-1.220000 |
|
| hsa-miR-548ab |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.098000 | -0.150000 |
-0.010000 |
|
| hsa-miR-548ak |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.098000 | -0.141000 |
-0.550000 |
|
| hsa-miR-548am-5p |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.098000 | -0.141000 |
-1.170000 |
|
| hsa-miR-548ap-5p |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.117000 | -0.169000 |
-0.020000 |
|
| hsa-miR-548aq-5p |
ataaggtTTACTTTCatac |
5 |
GAAAGUAA | m8a | Created | -0.098000 | -0.141000 |
-0.010000 |
|
| hsa-miR-548ar-5p |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.117000 | -0.160000 |
-0.900000 |
|
| hsa-miR-548as-5p |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.098000 | -0.123000 |
-0.010000 |
|
| hsa-miR-548au-5p |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.098000 | -0.141000 |
-0.490000 |
|
| hsa-miR-548b-5p |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.098000 | -0.141000 |
-0.030000 |
|
| hsa-miR-548c-5p |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.098000 | -0.141000 |
-1.170000 |
|
| hsa-miR-548d-5p |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.098000 | -0.141000 |
-0.040000 |
|
| hsa-miR-548h-5p |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.098000 | -0.141000 |
-2.020000 |
|
| hsa-miR-548i |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.098000 | -0.150000 |
-0.510000 |
|
| hsa-miR-548j |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.117000 | -0.169000 | No effect | |
| hsa-miR-548o-5p |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.098000 | -0.141000 |
-1.170000 |
|
| hsa-miR-548w |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.098000 | -0.141000 |
-1.940000 |
|
| hsa-miR-548y |
ataaggtTTACTTTcatac |
5 |
AAAAGUAA | m7b | Created | -0.098000 | -0.141000 |
-0.440000 |
|
| hsa-miR-559 |
ataaggtTTACTTTcatac |
5 |
UAAAGUAA | m7b | Created | -0.108000 | -0.160000 |
-0.020000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr17:g.58999169T>A | COSN5418642 | RK309_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3133 |
tgggaagaGTTCTTTgtaa |
6 |
UAAAGAAC | m7b | Disrupted | -0.098000 | -0.007000 |
3.370000 |
|
| hsa-miR-3156-5p |
tgggaagAGATCTTTgtaa |
0 | AAAGAUCU | m8a | Created | no TS | -0.107000 |
-0.270000 |
|
| hsa-miR-4511 |
tgggaagAGTTCTTtgtaa |
6 |
GAAGAACU | m7b | Disrupted | -0.123000 | no TS |
1.500000 |
|
| hsa-miR-4680-5p |
tgggaAGAGTTCTttgtaa |
8 |
AGAACUCU | m8a | Disrupted | -0.199000 | no TS |
3.360000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr17:g.58999255T>C | COSN1724369 | RK091_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-205-3p |
atctcgacCTGAAATagta |
4 |
GAUUUCAG | m7b | Disrupted | -0.149000 | no TS |
0.330000 |
| hsa-miR-431-3p |
atctCGACCTGaaatagta |
0 | CAGGUCGU | m7a | Disrupted | NA | NA |
4.250000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 58998618 | rs191702204 | T | |||||||
| C |
hsa-miR-548a-5p hsa-miR-548ab hsa-miR-548ak hsa-miR-548am-5p hsa-miR-548ap-5p hsa-miR-548aq-5p hsa-miR-548ar-5p hsa-miR-548as-5p hsa-miR-548au-5p hsa-miR-548av-5p hsa-miR-548ay-5p hsa-miR-548b-5p hsa-miR-548c-5p hsa-miR-548d-5p hsa-miR-548h-5p hsa-miR-548i hsa-miR-548j-5p hsa-miR-548k hsa-miR-548l hsa-miR-548o-5p hsa-miR-548w hsa-miR-548y hsa-miR-559 hsa-miR-8054 |
8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 4 8 8 8 8 8 |
caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaATACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa caaaTACTTTAaa |
Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created |
N N N N N N N N N N N N N N N N N N N N N N N N |
0.018 0.015 0.012 0.012 0.018 0.005 0.012 0.018 0.012 0.004 0.012 0.012 0.012 0.012 0.012 0.018 0.018 0.004 -0.078 0.012 0.012 0.005 -0.002 0.015 |
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| 58999004 | rs145973955 | A | A |
hsa-miR-2278 hsa-miR-4645-3p hsa-miR-4732-5p hsa-miR-936 |
1 1 1 1 |
TGCTCTActgtct tgctcTACTGTCt tGCTCTACtgtct tgcTCTACTGtct |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.067 -0.113 -0.177 -0.09 |
| G |
hsa-miR-6501-3p hsa-miR-922 |
1 1 |
TGCTCTGctgtct tgcTCTGCTGtct |
Created Created |
N N |
-0.098 -0.068 |