SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_001204192 |
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Gene Symbol: | TP73 |
Description: | Homo sapiens tumor protein p73 (TP73), transcript variant 2, mRNA. |
Gene Location: | chr1(+):3614609-3652765 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr1:g.3733327G>T | COSN1103580 | BN02T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3943 |
ttgtggggcGGGGGCTggc |
2 |
UAGCCCCC | m7b | (m7b->m6c) | -0.453000 | -0.314000 | No effect |
hsa-miR-4323 |
ttgtggggcTGGGGCTGgc |
0 | CAGCCCCA | m8a | (m7b->m8a) | no TS | -0.210000 |
-0.120000 |
hsa-miR-3943 |
ttgtggggcGGGGGCTggc |
0 | UAGCCCCC | m7b | (m7b->m6c) | -0.453 | -0.314 | No effect |
hsa-miR-4323 |
ttgtggggcTGGGGCTGgc |
0 | CAGCCCCA | m8a | (m7b->m8a) | no TS | -0.21 |
-0.12 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr1:g.3734201G>A | COSN10047886 | C0004T | [kidney][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4732-3p |
gcggtggcaGTCAGGGaac |
2 |
GCCCUGAC | m7b | (m7b->m6c) | -0.278000 | -0.168000 |
0.290000 |
hsa-miR-5002-3p |
gcggtGGCAGTCAgggaac |
2 |
UGACUGCC | m8a | Disrupted | -0.145000 | no TS |
0.070000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr1:g.3734741C>T | COSN7218293 | 8031704 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-376a-3p |
cctggTCTATGAagacgca |
0 | AUCAUAGA | m7b | Created | no TS | 0.193000 | No effect |
hsa-miR-376b |
cctggTCTATGAagacgca |
0 | AUCAUAGA | m7b | Created | no TS | 0.193000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr1:g.3735047A>C | COSN8468010 | AOCS-034-3-8 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-185-3p |
ggcgCAGCCCCcccagctg |
0 | AGGGGCUG | m7b | Created | -0.063000 | -0.051000 |
-0.020000 |
hsa-miR-342-5p |
ggcgcagcCACCCCagctg |
2 |
AGGGGUGC | m6b | Disrupted | -0.182000 | -0.157000 | No effect |
hsa-miR-4483 |
ggcgcagCCACCCCagctg |
0 | GGGGUGGU | m7a | Disrupted | -0.021000 | -0.021000 | No effect |
hsa-miR-4651 |
ggcgcagCCACCCCagctg |
0 | CGGGGUGG | m7b | Disrupted | -0.090000 | -0.015000 | No effect |
hsa-miR-608 |
ggcgcagCCACCCCagctg |
0 | AGGGGUGG | m7b | Disrupted | -0.104000 | -0.018000 | No effect |
hsa-miR-637 |
ggcgcagccCCCCCAGctg |
2 |
ACUGGGGG | m7b | (m6c->m7b) | -0.353000 | -0.352000 | No effect |
hsa-miR-647 |
ggcGCAGCCACcccagctg |
0 | GUGGCUGC | m8a | Disrupted | -0.440000 | -0.475000 | No effect |