SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001204186
Gene Symbol: TP73
Description: Homo sapiens tumor protein p73 (TP73), transcript variant 2, mRNA.
Gene Location: chr1(+):3569128-3652765
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr1:g.3733327G>T COSN1103580 BN02T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3943 ttgtggggcGGGGGCTggc
 0 UAGCCCCC m7b (m7b->m6c) -0.363000 -0.269000 No effect
hsa-miR-4323 ttgtggggcTGGGGCTGgc
 0 CAGCCCCA m8a (m7b->m8a) no TS -0.120000 -0.120000
hsa-miR-3943 ttgtggggcGGGGGCTggc
 0 UAGCCCCC m7b (m7b->m6c) -0.363 -0.269 No effect
hsa-miR-4323 ttgtggggcTGGGGCTGgc
 0 CAGCCCCA m8a (m7b->m8a) no TS -0.12 -0.12

Mutation Mutation ID Sample Name Cancer Type
chr1:g.3734201G>A COSN10047886 C0004T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4732-3p gcggtggcaGTCAGGGaac
 2
 GCCCUGAC m7b (m7b->m6c) -0.163000 -0.098000 0.290000
hsa-miR-5002-3p gcggtGGCAGTCAgggaac
 2
 UGACUGCC m8a Disrupted -0.065000 no TS 0.070000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.3734741C>T COSN7218293 8031704 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-376a-3p cctggTCTATGAagacgca
 0 AUCAUAGA m7b Created no TS 0.193000 No effect
hsa-miR-376b cctggTCTATGAagacgca
 0 AUCAUAGA m7b Created no TS 0.193000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr1:g.3735047A>C COSN8468010 AOCS-034-3-8 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-185-3p ggcgCAGCCCCcccagctg
 0 AGGGGCUG m7b Created -0.063000 -0.051000 -0.030000
hsa-miR-342-5p ggcgcagcCACCCCagctg
 2
 AGGGGUGC m6b Disrupted -0.102000 -0.077000 No effect
hsa-miR-4483 ggcgcagCCACCCCagctg
 0 GGGGUGGU m7a Disrupted 0.004000 0.004000 No effect
hsa-miR-4651 ggcgcagCCACCCCagctg
 0 CGGGGUGG m7b Disrupted -0.055000 0.020000 No effect
hsa-miR-608 ggcgcagCCACCCCagctg
 0 AGGGGUGG m7b Disrupted -0.069000 0.017000 No effect
hsa-miR-637 ggcgcagccCCCCCAGctg
 2
 ACUGGGGG m7b (m6c->m7b) -0.263000 -0.262000 No effect
hsa-miR-647 ggcGCAGCCACcccagctg
 0 GUGGCUGC m8a Disrupted -0.360000 -0.395000 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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