SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001126116
Gene Symbol: TP53
Description: Homo sapiens tumor protein p53 (TP53), transcript variant 1, mRNA.
Gene Location: chr17(-):7571719-7578811
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr17:g.7668450C>T 0_24 Melanoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr17:g.7668750G>A cosmic_v64_1760522 Leukemia/T-ALL
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3150a-3p tgcCTCCCCAGctcgagca
 0 CUGGGGAG m8a Created no TS -0.078 No effect
hsa-miR-4487 tgcctccCCAGCTCgagca
 0 AGAGCUGG m7b Created no TS -0.107 -2.8
hsa-miR-4667-5p tgccTCCCCAGctcgagca
 0 ACUGGGGA m7b Created no TS -0.129 -0.38
hsa-miR-4700-5p tgccTCCCCAGctcgagca
 0 UCUGGGGA m7b Created no TS -0.082 -2.8
hsa-miR-4731-5p tgcctCCCCAGCtcgagca
 0 UGCUGGGG m7b Created no TS -0.163 -1.59


Mutation Mutation ID Sample Name Cancer Type
chr17:g.7668837T>C 9_79159 CRC-7-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr17:g.7669668T>T ICGC_49411 TCGA-DK-A1AC-01A-11D-A13W-08 BladderUrothelialCarcinoma(TCGA,US)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-151a-3p aaaaagggtCAGTCTAcct
 0 CUAGACUG m7b (m7b->m6b) -0.147 no TS 0.06
hsa-miR-4463 aaaaagggtCAGTCTacct
 0 GAGACUGG m6b Disrupted -0.071 no TS No effect
hsa-miR-4499 aaaaagggTCAGTCTacct
 0 AAGACUGA m7b Disrupted -0.233 no TS No effect
hsa-miR-4513 aaaaaggGTCAGTCTacct
 0 AGACUGAC m8a Disrupted -0.18 no TS 0.08
hsa-miR-4725-5p aaaaAGGGTCagtctacct
 0 AGACCCUG m6b Disrupted -0.756 -0.587 1.21
hsa-miR-504 aaaaAGGGTCagtctacct
 0 AGACCCUG m6b Disrupted -0.766 -0.608 1.68
hsa-miR-652-5p aaaaAGGGTTagtctacct
 0 CAACCCUA m6b Created -0.212 -0.344 -4.2

Mutation Mutation ID Sample Name Cancer Type
chr17:g.7670664G>T ICGC_ssm_v3_21357 BN49T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4424 gaggccttgTAACTCaagg
 0 AGAGUUAA m6b Created no TS -0.06 -10.335
hsa-miR-624-3p gaggCCTTGTaactcaagg
 0 CACAAGGU m6b Created no TS -0.093 -1.23

Mutation Mutation ID Sample Name Cancer Type
chr17:g.7670665G>T ICGC_ssm_v3_21358 BN49T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3922-5p tgaGGCCTTGgaactcaag
 0 UCAAGGCC m7b (m7b->m6c) -0.539 -0.317 0.07

Mutation Mutation ID Sample Name Cancer Type
chr17:g.7670685C>T ICGC_0085_SNP_97258 8012347 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3615 gagatgttCCGAGAGctga
 0 UCUCUCGG m7b Disrupted -0.312 no TS -0.04
hsa-miR-3917 gagatgtTCCGAGagctga
 0 GCUCGGAC m6b Disrupted -0.197 no TS No effect
hsa-miR-4330 gagatgtTCTGAGagctga
 0 CCUCAGAU m6b Created no TS -0.073 -0.08
hsa-miR-4773 gagaTGTTCTGagagctga
 0 CAGAACAG m7a Created NA NA No effect
hsa-miR-589-3p gagaTGTTCTGAgagctga
 0 UCAGAACA m8a Created no TS -0.232 No effect

Mutation Mutation ID Sample Name Cancer Type
chr17:g.7670699G>A ICGC_ssm_v3_68964 HCC123T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1178 ggcGTGAGCActtcgagat
 0 UUGCUCAC m7b (m6c->m7b) no TS -0.122 -1.4
hsa-miR-302a-3p ggcgtgAGCACTTcgagat
 0 UAAGUGCU m7b Created no TS -0.054 -0.01
hsa-miR-302b-3p ggcgtgAGCACTTcgagat
 0 UAAGUGCU m7b Created no TS -0.054 -0.12
hsa-miR-302c-3p ggcgtgAGCACTTcgagat
 0 UAAGUGCU m7b Created no TS -0.054 No effect
hsa-miR-302d-3p ggcgtgAGCACTTcgagat
 0 UAAGUGCU m7b Created no TS -0.054 -0.02
hsa-miR-302e ggcgtgAGCACTTcgagat
 0 UAAGUGCU m7b Created no TS -0.072 -0.11
hsa-miR-372 ggcgtgAGCACTTcgagat
 0 AAAGUGCU m7b Created no TS -0.072 -0.03
hsa-miR-373-3p ggcgtgAGCACTTCgagat
 0 GAAGUGCU m8a Created no TS -0.054 No effect
hsa-miR-518e-3p ggcgtgAGCGCTTcgagat
 0 AAAGCGCU m7b Disrupted -0.219 no TS 5.31
hsa-miR-520a-3p ggcgtgAGCACTTcgagat
 0 AAAGUGCU m7b Created no TS -0.072 No effect
hsa-miR-520b ggcgtgAGCACTTcgagat
 0 AAAGUGCU m7b Created no TS -0.054 No effect
hsa-miR-520c-3p ggcgtgAGCACTTcgagat
 0 AAAGUGCU m7b Created no TS -0.054 No effect
hsa-miR-520d-3p ggcgtgAGCACTTcgagat
 0 AAAGUGCU m7b Created no TS -0.063 No effect
hsa-miR-520e ggcgtgAGCACTTcgagat
 0 AAAGUGCU m7b Created no TS -0.054 No effect

Mutation Mutation ID Sample Name Cancer Type
chr17:g.7673215G>A cosmic_v64_1760519 Leukemia/T-ALL
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1305 tcgtaaGTTGAAAAtatt
 0 UUUUCAAC m8a Disrupted -0.197 no TS 5.91


Mutation Mutation ID Sample Name Cancer Type
chr17:g.7673252A>C ICGC_ssm_v3_125114 HCC60T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr17:g.7673289T>A cosmic_v64_1760522 Leukemia/T-ALL
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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