SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001126113
Gene Symbol: TP53
Description: Homo sapiens tumor protein p53 (TP53), transcript variant 1, mRNA.
Gene Location: chr17(-):7571719-7590863
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Browse Pathways

Somatic mutations that impact miRNA target sites




Mutation Mutation ID Sample Name Cancer Type
chr17:g.7668450C>T 0_24 Melanoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr17:g.7668750G>A cosmic_v64_1760522 Leukemia/T-ALL
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3150a-3p tgcCTCCCCAGctcgagca
0 CUGGGGAG m8a Created no TS -0.078 No effect
hsa-miR-4487 tgcctccCCAGCTCgagca
0 AGAGCUGG m7b Created no TS -0.107 -2.8
hsa-miR-4667-5p tgccTCCCCAGctcgagca
0 ACUGGGGA m7b Created no TS -0.129 -0.38
hsa-miR-4700-5p tgccTCCCCAGctcgagca
0 UCUGGGGA m7b Created no TS -0.082 -2.8
hsa-miR-4731-5p tgcctCCCCAGCtcgagca
0 UGCUGGGG m7b Created no TS -0.163 -1.59


Mutation Mutation ID Sample Name Cancer Type
chr17:g.7668837T>C 9_79159 CRC-7-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr17:g.7669668T>T ICGC_49411 TCGA-DK-A1AC-01A-11D-A13W-08 BladderUrothelialCarcinoma(TCGA,US)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-151a-3p aaaaagggtCAGTCTAcct
0 CUAGACUG m7b (m7b->m6b) -0.16 no TS 0.06
hsa-miR-4463 aaaaagggtCAGTCTacct
0 GAGACUGG m6b Disrupted -0.081 no TS No effect
hsa-miR-4499 aaaaagggTCAGTCTacct
0 AAGACUGA m7b Disrupted -0.256 no TS No effect
hsa-miR-4513 aaaaaggGTCAGTCTacct
0 AGACUGAC m8a Disrupted -0.192 no TS 0.08
hsa-miR-4725-5p aaaaAGGGTCagtctacct
0 AGACCCUG m6b Disrupted -0.766 -0.587 1.21
hsa-miR-504 aaaaAGGGTCagtctacct
0 AGACCCUG m6b Disrupted -0.776 -0.608 1.68
hsa-miR-652-5p aaaaAGGGTTagtctacct
0 CAACCCUA m6b Created -0.231 -0.373 -4.2

Mutation Mutation ID Sample Name Cancer Type
chr17:g.7670664G>T ICGC_ssm_v3_21357 BN49T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4424 gaggccttgTAACTCaagg
0 AGAGUUAA m6b Created no TS -0.07 -0.87
hsa-miR-624-3p gaggCCTTGTaactcaagg
0 CACAAGGU m6b Created no TS -0.103 -2.12

Mutation Mutation ID Sample Name Cancer Type
chr17:g.7670665G>T ICGC_ssm_v3_21358 BN49T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3922-5p tgaGGCCTTGgaactcaag
0 UCAAGGCC m7b (m7b->m6c) -0.574 -0.339 0.03

Mutation Mutation ID Sample Name Cancer Type
chr17:g.7670685C>T ICGC_0085_SNP_97258 8012347 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3615 gagatgttCCGAGAGctga
0 UCUCUCGG m7b Disrupted -0.325 no TS -0.04
hsa-miR-4330 gagatgtTCTGAGagctga
0 CCUCAGAU m6b Created no TS -0.083 -0.07
hsa-miR-4773 gagaTGTTCTGagagctga
0 CAGAACAG m7a Created NA NA No effect
hsa-miR-3917 gagatgtTCCGAGagctga
0 GCUCGGAC m6b Disrupted -0.207 no TS -16.92
hsa-miR-589-3p gagaTGTTCTGAgagctga
0 UCAGAACA m8a Created no TS -0.255 -8.28

Mutation Mutation ID Sample Name Cancer Type
chr17:g.7670699G>A ICGC_ssm_v3_68964 HCC123T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1178 ggcGTGAGCActtcgagat
0 UUGCUCAC m7b (m6c->m7b) no TS -0.132 -1.11
hsa-miR-302a-3p ggcgtgAGCACTTcgagat
0 UAAGUGCU m7b Created no TS -0.064 No effect
hsa-miR-302b-3p ggcgtgAGCACTTcgagat
0 UAAGUGCU m7b Created no TS -0.064 -0.03
hsa-miR-302c-3p ggcgtgAGCACTTcgagat
0 UAAGUGCU m7b Created no TS -0.064 No effect
hsa-miR-302d-3p ggcgtgAGCACTTcgagat
0 UAAGUGCU m7b Created no TS -0.064 No effect
hsa-miR-302e ggcgtgAGCACTTcgagat
0 UAAGUGCU m7b Created no TS -0.082 -0.03
hsa-miR-372 ggcgtgAGCACTTcgagat
0 AAAGUGCU m7b Created no TS -0.082 -0.01
hsa-miR-373-3p ggcgtgAGCACTTCgagat
0 GAAGUGCU m8a Created no TS -0.064 No effect
hsa-miR-518e-3p ggcgtgAGCGCTTcgagat
0 AAAGCGCU m7b Disrupted -0.229 no TS 3.65
hsa-miR-520a-3p ggcgtgAGCACTTcgagat
0 AAAGUGCU m7b Created no TS -0.082 No effect
hsa-miR-520b ggcgtgAGCACTTcgagat
0 AAAGUGCU m7b Created no TS -0.064 No effect
hsa-miR-520c-3p ggcgtgAGCACTTcgagat
0 AAAGUGCU m7b Created no TS -0.064 No effect
hsa-miR-520d-3p ggcgtgAGCACTTcgagat
0 AAAGUGCU m7b Created no TS -0.073 No effect
hsa-miR-520e ggcgtgAGCACTTcgagat
0 AAAGUGCU m7b Created no TS -0.064 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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