SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_001126113 |
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Gene Symbol: | TP53 |
Description: | Homo sapiens tumor protein p53 (TP53), transcript variant 1, mRNA. |
Gene Location: | chr17(-):7571719-7590863 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr17:g.7668450C>T | 0_24 | Melanoma | ||||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr17:g.7668750G>A | cosmic_v64_1760522 | Leukemia/T-ALL | ||||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3150a-3p |
tgcCTCCCCAGctcgagca |
0 | CUGGGGAG | m8a | Created | no TS | -0.078 | No effect |
hsa-miR-4487 |
tgcctccCCAGCTCgagca |
0 | AGAGCUGG | m7b | Created | no TS | -0.107 |
-2.8 |
hsa-miR-4667-5p |
tgccTCCCCAGctcgagca |
0 | ACUGGGGA | m7b | Created | no TS | -0.129 |
-0.38 |
hsa-miR-4700-5p |
tgccTCCCCAGctcgagca |
0 | UCUGGGGA | m7b | Created | no TS | -0.082 |
-2.8 |
hsa-miR-4731-5p |
tgcctCCCCAGCtcgagca |
0 | UGCUGGGG | m7b | Created | no TS | -0.163 |
-1.59 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr17:g.7668837T>C | 9_79159 | CRC-7-Tumor | Colorectal adenocarcinoma | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr17:g.7669668T>T | ICGC_49411 | TCGA-DK-A1AC-01A-11D-A13W-08 | BladderUrothelialCarcinoma(TCGA,US) | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-151a-3p |
aaaaagggtCAGTCTAcct |
0 | CUAGACUG | m7b | (m7b->m6b) | -0.16 | no TS |
0.06 |
hsa-miR-4463 |
aaaaagggtCAGTCTacct |
0 | GAGACUGG | m6b | Disrupted | -0.081 | no TS | No effect |
hsa-miR-4499 |
aaaaagggTCAGTCTacct |
0 | AAGACUGA | m7b | Disrupted | -0.256 | no TS | No effect |
hsa-miR-4513 |
aaaaaggGTCAGTCTacct |
0 | AGACUGAC | m8a | Disrupted | -0.192 | no TS |
0.08 |
hsa-miR-4725-5p |
aaaaAGGGTCagtctacct |
0 | AGACCCUG | m6b | Disrupted | -0.766 | -0.587 |
1.21 |
hsa-miR-504 |
aaaaAGGGTCagtctacct |
0 | AGACCCUG | m6b | Disrupted | -0.776 | -0.608 |
1.68 |
hsa-miR-652-5p |
aaaaAGGGTTagtctacct |
0 | CAACCCUA | m6b | Created | -0.231 | -0.373 |
-4.2 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr17:g.7670664G>T | ICGC_ssm_v3_21357 | BN49T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4424 |
gaggccttgTAACTCaagg |
0 | AGAGUUAA | m6b | Created | no TS | -0.07 |
-0.87 |
hsa-miR-624-3p |
gaggCCTTGTaactcaagg |
0 | CACAAGGU | m6b | Created | no TS | -0.103 |
-2.12 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr17:g.7670665G>T | ICGC_ssm_v3_21358 | BN49T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3922-5p |
tgaGGCCTTGgaactcaag |
0 | UCAAGGCC | m7b | (m7b->m6c) | -0.574 | -0.339 |
0.03 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr17:g.7670685C>T | ICGC_0085_SNP_97258 | 8012347 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3615 |
gagatgttCCGAGAGctga |
0 | UCUCUCGG | m7b | Disrupted | -0.325 | no TS |
-0.04 |
hsa-miR-4330 |
gagatgtTCTGAGagctga |
0 | CCUCAGAU | m6b | Created | no TS | -0.083 |
-0.07 |
hsa-miR-4773 |
gagaTGTTCTGagagctga |
0 | CAGAACAG | m7a | Created | NA | NA | No effect |
hsa-miR-3917 |
gagatgtTCCGAGagctga |
0 | GCUCGGAC | m6b | Disrupted | -0.207 | no TS |
-16.92 |
hsa-miR-589-3p |
gagaTGTTCTGAgagctga |
0 | UCAGAACA | m8a | Created | no TS | -0.255 |
-8.28 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr17:g.7670699G>A | ICGC_ssm_v3_68964 | HCC123T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1178 |
ggcGTGAGCActtcgagat |
0 | UUGCUCAC | m7b | (m6c->m7b) | no TS | -0.132 |
-1.11 |
hsa-miR-302a-3p |
ggcgtgAGCACTTcgagat |
0 | UAAGUGCU | m7b | Created | no TS | -0.064 | No effect |
hsa-miR-302b-3p |
ggcgtgAGCACTTcgagat |
0 | UAAGUGCU | m7b | Created | no TS | -0.064 |
-0.03 |
hsa-miR-302c-3p |
ggcgtgAGCACTTcgagat |
0 | UAAGUGCU | m7b | Created | no TS | -0.064 | No effect |
hsa-miR-302d-3p |
ggcgtgAGCACTTcgagat |
0 | UAAGUGCU | m7b | Created | no TS | -0.064 | No effect |
hsa-miR-302e |
ggcgtgAGCACTTcgagat |
0 | UAAGUGCU | m7b | Created | no TS | -0.082 |
-0.03 |
hsa-miR-372 |
ggcgtgAGCACTTcgagat |
0 | AAAGUGCU | m7b | Created | no TS | -0.082 |
-0.01 |
hsa-miR-373-3p |
ggcgtgAGCACTTCgagat |
0 | GAAGUGCU | m8a | Created | no TS | -0.064 | No effect |
hsa-miR-518e-3p |
ggcgtgAGCGCTTcgagat |
0 | AAAGCGCU | m7b | Disrupted | -0.229 | no TS |
3.65 |
hsa-miR-520a-3p |
ggcgtgAGCACTTcgagat |
0 | AAAGUGCU | m7b | Created | no TS | -0.082 | No effect |
hsa-miR-520b |
ggcgtgAGCACTTcgagat |
0 | AAAGUGCU | m7b | Created | no TS | -0.064 | No effect |
hsa-miR-520c-3p |
ggcgtgAGCACTTcgagat |
0 | AAAGUGCU | m7b | Created | no TS | -0.064 | No effect |
hsa-miR-520d-3p |
ggcgtgAGCACTTcgagat |
0 | AAAGUGCU | m7b | Created | no TS | -0.073 | No effect |
hsa-miR-520e |
ggcgtgAGCACTTcgagat |
0 | AAAGUGCU | m7b | Created | no TS | -0.064 | No effect |