SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_014729
Gene Symbol: TOX
Description: Homo sapiens thymocyte selection-associated high mobility group box (TOX), mRNA.
Gene Location: chr8(-):59717976-60031767
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr8:g.58805485A>G COSN4881523 tumor_4104893 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1256 aaattCAATGCCaaataca
0 AGGCAUUG m7b Created no TS -0.493000 -3.100000
hsa-miR-1271-5p aaattcaaTGCCAAataca
20
CUUGGCAC m6b Created -0.089000 -0.259000 -3.050000
hsa-miR-4642 aaattcaATGCCAaataca
0 AUGGCAUC m6b Created no TS -0.165000 -14.290000
hsa-miR-5002-5p aaattcaatACCAAATaca
9
AAUUUGGU m7b (m7b->m6b) -0.313000 -0.090000 No effect
hsa-miR-5681b aaattCAATACCaaataca
0 AGGUAUUG m7b Disrupted -0.422000 no TS -0.080000

Mutation Mutation ID Sample Name Cancer Type
chr8:g.58806217T>C COSN2282407 RK021_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3622a-5p gctgtctttCGTGCCTcta
0 CAGGCACG m7b (m6b->m7b) no TS -0.220000 -2.780000
hsa-miR-5582-5p gctgtctttTGTGCCTcta
0 UAGGCACA m7b (m7b->m6b) -0.178000 no TS 1.210000
hsa-miR-3622a-5p gctgtctttCGTGCCTcta
0 CAGGCACG m7b (m6b->m7b) no TS -0.22 -2.78
hsa-miR-5582-5p gctgtctttTGTGCCTcta
0 UAGGCACA m7b (m7b->m6b) -0.178 no TS 1.21

Mutation Mutation ID Sample Name Cancer Type
chr8:g.58806838T>A COSN8093242 8035543 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-587 atcttttttTATGGAAcct
0 UUUCCAUA m7b (m7b->m6b) -0.042000 no TS 1.060000
hsa-miR-885-5p atctttttTAATGGAacct
17
UCCAUUAC m7a Created -0.151000 -0.161000 -0.100000

Mutation Mutation ID Sample Name Cancer Type
chr8:g.58807514C>T COSN1366531 HCC87T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4427 aatttggacTATTCAGAtt
16
UCUGAAUA m8a (m7a->m8a) -0.062000 -0.196000 -2.030000
hsa-miR-4790-3p aatttggACCATTCAgatt
15
UGAAUGGU m8a Disrupted -0.280000 no TS 1.460000
hsa-miR-5585-3p aatttggaCTATTCAGatt
0 CUGAAUAG m8a Created no TS -0.120000 -0.340000
hsa-miR-4427 aatttggacTATTCAGAtt
0 UCUGAAUA m8a (m7a->m8a) -0.062 -0.196 -2.03
hsa-miR-4790-3p aatttggACCATTCAgatt
0 UGAAUGGU m8a Disrupted -0.28 no TS 1.46
hsa-miR-5585-3p aatttggaCTATTCAGatt
0 CUGAAUAG m8a Created no TS -0.12 -0.34

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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