SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_148957
Gene Symbol:	TNFRSF19
Description:	Homo sapiens tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), transcript variant 3, mRNA.
Gene Location:	chr13(+):24144508-24250244
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Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr13:g.23673437T>C			COSN7396286		8066852		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-495	gtactccTTTGTTaggctt	2	AAACAAAC	m6b	Disrupted	0.044000	no TS	0.020000
hsa-miR-7-1-3p	gtactccTTTGTTaggctt	2	CAACAAAU	m6b	Disrupted	0.120000	0.082000	0.140000
hsa-miR-7-2-3p	gtactccTTTGTTaggctt	2	CAACAAAU	m6b	Disrupted	0.111000	0.073000	1.250000

Mutation			Mutation ID		Sample Name		Cancer Type
chr13:g.23675917G>T			COSN1603863		RK159_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
23674197	rs139705287	T	T	hsa-miR-3065-5p hsa-miR-33a-3p hsa-miR-7-1-3p hsa-miR-7-2-3p	6 2 5 5	gaaacaTTTGTTG gAAACATTtgttg gaaacATTTGTTg gaaacATTTGTTg	Disrupted Disrupted Disrupted Disrupted	N N N N	0.002 0.062 0.082 0.073
			C	hsa-miR-6513-3p	1	gaaACACTTGttg	Created	N	-0.101

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