SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001184718
Gene Symbol: TIPARP
Description: Homo sapiens TCDD-inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant 1, mRNA.
Gene Location: chr3(+):156394452-156424557
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr3:g.156705283A>T 9_85771 CRC-8-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr3:g.156705284A>T COSN4812743 tumor_4159170 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][follicular_lymphoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3163 ctttTTTTATAaaaaaaat
 0 UAUAAAAU m7a Created no TS 0.031000 No effect
hsa-miR-340-5p cttttTTTATAAaaaaaat
 0 UUAUAAAG m7a Created no TS 0.005000 No effect
hsa-miR-3163 ctttTTTTATAaaaaaaat
 0 UAUAAAAU m7a Created no TS 0.031000 No effect
hsa-miR-340-5p cttttTTTATAAaaaaaat
 0 UUAUAAAG m7a Created no TS 0.005000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.156705743T>C COSN8488547 J76_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-146a-3p agttctaTTCAGAGGaagt
 4
 CCUCUGAA m8a Created -0.242000 -0.353000 0.210000
hsa-miR-3121-3p agtTCTATTTAgaggaagt
 1
 UAAAUAGA m8a Disrupted -0.132000 -0.123000 0.140000
hsa-miR-4427 agttcTATTCAGAggaagt
 5
 UCUGAAUA m8a Created 0.007000 -0.112000 -1.600000
hsa-miR-4799-5p agttctATTTAGAggaagt
 1
 AUCUAAAU m7b Disrupted 0.060000 0.053000 0.010000
hsa-miR-5187-3p agttctATTCAGaggaagt
 5
 ACUGAAUC m6b Created 0.008000 0.013000 -2.000000
hsa-miR-5585-3p agttCTATTCAGaggaagt
 0 CUGAAUAG m8a Created no TS -0.067000 -1.620000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.156705783A>C 8_2353 182896 Myeloid leukemia
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1305 ccatTTGAAAAatttttgt
 14
 UUUUCAAC m7a Disrupted 0.032 no TS 0.01
hsa-miR-335-3p ccattTGAAAAAtttttgt
 12
 UUUUUCAU m7a Disrupted 0.04 no TS No effect
hsa-miR-607 ccATTTGAACaatttttgt
 12
 GUUCAAAU m8a (m7a->m8a) 0.175 0.184 0.01

Mutation Mutation ID Sample Name Cancer Type
chr3:g.156706242C>G COSN6738019 RK200_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-21-3p gtgaataTGGTGTTtcctc
 0 CAACACCA m7b Created no TS -0.125000 -1.710000
hsa-miR-3591-3p gtgaataTGGTGTTTcctc
 0 AAACACCA m8a Created no TS -0.162000 -8.330000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.156706574T>G 9_2040 CRC-2-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-194-5p ctgtggCTGTTACAgttct
 0 UGUAACAG m8a Disrupted -0.221 no TS 1.19
hsa-miR-4691-3p ctGTGGCTGGtacagttct
 0 CCAGCCAC m8a (m7a->m8a) -0.332 -0.305 -0.07
hsa-miR-634 ctgtgGCTGGTacagttct
 0 AACCAGCA m6b Created no TS -0.168 -3.05

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
156705284 rs185161634 A
T hsa-miR-3163
hsa-miR-340-5p
1
1
 tTTTTATAaaaaa
ttTTTATAAaaaa
 Created
Created
N
N
 0.031
0.005
156706144 rs187348713 G G hsa-miR-3157-5p
hsa-miR-4691-3p
hsa-miR-7113-5p
16
16
11
 tcccTGGCTGAct
tcccTGGCTGAct
TCCCTGGctgact
 Disrupted
Disrupted
Disrupted
N
N
N
 -0.075
-0.072
-0.153
A hsa-miR-211-3p
hsa-miR-4270
hsa-miR-4441
hsa-miR-4704-3p
hsa-miR-6754-5p
11
11
11
16
11
 TCCCTGActgact
TCCCTGActgact
TCCCTGActgact
tcccTGACTGAct
TCCCTGActgact
 Created
Created
Created
Created
Created
N
N
N
N
N
 -0.065
-0.049
-0.062
-0.038
-0.049

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