SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
  Home Search Help Download  

PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_014464
Gene Symbol: TINAG
Description: Homo sapiens tubulointerstitial nephritis antigen (TINAG), mRNA.
Gene Location: chr6(+):54173202-54254950
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr6:g.54390129A>T COSN7886987 8030353 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3199 ggacagcagAGTCCCTaaa
0 AGGGACUG m7a (m7a->m6b) NA NA 3.630000
hsa-miR-365a-5p ggacagcagAGTCCCTaaa
0 AGGGACUU m7a (m7a->m6b) NA NA 4.330000
hsa-miR-365b-5p ggacagcagAGTCCCTaaa
0 AGGGACUU m7a (m7a->m6b) NA NA 4.260000
hsa-miR-4522 ggacagCAGAGTCcctaaa
1
UGACUCUG m7b Disrupted -0.197000 no TS 4.500000

Mutation Mutation ID Sample Name Cancer Type
chr6:g.54390134C>T COSN4859885 tumor_4104893 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2909 gcagagtCCCTAAatgtct
2
GUUAGGGC m6b Disrupted -0.318000 -0.169000 0.360000
hsa-miR-3162-5p gcagagTCCCTAAatgtct
0 UUAGGGAG m7a Disrupted -0.177000 no TS 0.060000
hsa-miR-3199 gcagAGTCCCTaaatgtct
0 AGGGACUG m7a Disrupted NA NA 5.300000
hsa-miR-365a-5p gcagAGTCCCTaaatgtct
0 AGGGACUU m7a Disrupted NA NA 8.750000
hsa-miR-365b-5p gcagAGTCCCTaaatgtct
0 AGGGACUU m7a Disrupted NA NA 9.150000
hsa-miR-4477b gcagagTCCTTAAatgtct
0 AUUAAGGA m7b Created no TS -0.267000 0.960000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table

Location SNP ID Ancestral
Allele
Allele miR ID Conservation miRSite FuncClass Validation context+
score change
54390130 rs115645370 G G hsa-miR-4522
hsa-miR-6728-3p
hsa-miR-7845-5p
1
4
13
agCAGAGTCccta
AGCAGAGtcccta
agcagaGTCCCTA
Disrupted
Disrupted
Disrupted
N
N
N
-0.197
-0.179
-0.196
T hsa-miR-4686
hsa-miR-5584-5p
hsa-miR-6750-5p
hsa-miR-6822-5p
4
13
13
13
AGCAGATtcccta
agcagaTTCCCTA
agcagaTTCCCTA
agcagaTTCCCTA
Created
Created
Created
Created
N
N
N
N
-0.205
-0.122
-0.155
-0.152

Genome Browser