SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_004612
Gene Symbol: TGFBR1
Description: Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 2, mRNA.
Gene Location: chr9(+):101867411-101916473
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr9:g.99149565A>G COSN6372187 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr9:g.99149734C>T COSN8113770 8044436 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1244 attctgAACTACTagagtt
 0 AAGUAGUU m7b Created no TS -0.187000 -0.020000
hsa-miR-140-5p attctgAACCACTagagtt
 13
 CAGUGGUU m7b Disrupted -0.256000 no TS 0.050000
hsa-miR-325 attctgaaCTACTAGagtt
 0 CCUAGUAG m7b Created no TS -0.315000 -0.110000
hsa-miR-4460 attctgaACCACTAgagtt
 13
 AUAGUGGU m7b Disrupted -0.315000 -0.112000 0.100000
hsa-miR-5000-5p attCTGAACTactagagtt
 11
 CAGUUCAG m7b (m6b->m7b) -0.114000 -0.378000 -1.250000

Mutation Mutation ID Sample Name Cancer Type
chr9:g.99150657T>A COSN8579763 tumor_4135099 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-141-3p ttCAGTGTTAccttatgtg
 8
 UAACACUG m8a (m7a->m8a) 0.056000 0.066000 No effect
hsa-miR-200a-3p ttCAGTGTTAccttatgtg
 8
 UAACACUG m8a (m7a->m8a) 0.065000 0.077000 No effect
hsa-miR-4261 ttcagTGTTTCCTtatgtg
 2
 AGGAAACA m8a Disrupted 0.019000 -0.018000 0.010000
hsa-miR-4496 ttcagtGTTTCCTtatgtg
 9
 GAGGAAAC m7b Disrupted -0.123000 -0.116000 0.060000
hsa-miR-548ag ttcagtgTTACCTTatgtg
 0 AAAGGUAA m7b Created 0.067000 0.154000 -0.220000
hsa-miR-548ai ttcagtgTTACCTTatgtg
 0 AAAGGUAA m7b Created 0.058000 0.145000 -0.600000
hsa-miR-570-5p ttcagtgTTACCTTatgtg
 0 AAAGGUAA m7b Created 0.058000 0.145000 -0.600000

Mutation Mutation ID Sample Name Cancer Type
chr9:g.99150734A>C COSN5117154 HX32T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-150-5p acTTGGGAGAggtggtagc
 10
 UCUCCCAA m8a (m8a->m7a) -0.168000 -0.151000 0.220000
hsa-miR-4713-5p actTGGGAGAggtggtagc
 2
 UUCUCCCA m7b (m7b->m6b) -0.067000 -0.037000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr9:g.99151396T>G COSN14598862 8058344 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3613-3p ttttTTTTTTGTttttttt
 0 ACAAAAAA m8a Disrupted 0.680000 0.704000 2.080000
hsa-miR-548aa ttttttttTGGTTTTTttt
 0 AAAAACCA m8a Created 0.275000 0.279000 0.820000
hsa-miR-548ac tttttttttGGTTTTTttt
 7
 CAAAAACC m7b (m6c->m7b) 0.672000 0.728000 0.150000
hsa-miR-548ap-3p ttttttttTGGTTTTTttt
 0 AAAAACCA m8a Created 0.275000 0.279000 0.540000
hsa-miR-548d-3p tttttttttGGTTTTTttt
 7
 CAAAAACC m7b (m6c->m7b) 0.709000 0.793000 0.040000
hsa-miR-548h-3p tttttttttGGTTTTTttt
 7
 CAAAAACC m7b (m6c->m7b) 0.681000 0.728000 0.080000
hsa-miR-548t-3p ttttttttTGGTTTTTttt
 0 AAAAACCA m8a Created 0.275000 0.279000 0.820000
hsa-miR-548z tttttttttGGTTTTTttt
 7
 CAAAAACC m7b (m6c->m7b) 0.681000 0.728000 0.080000

Mutation Mutation ID Sample Name Cancer Type
chr9:g.99153419C>T COSN8113771 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-let-7a-2-3p agataTGTACAGaaaatgt
 0 CUGUACAG m7a Disrupted NA NA No effect
hsa-let-7a-3p agataTGTATAGaaaatgt
 15
 CUAUACAA m7a Created -0.167000 -0.167000 -0.060000
hsa-let-7b-3p agataTGTATAGaaaatgt
 15
 CUAUACAA m7a Created -0.177000 -0.177000 No effect
hsa-let-7f-1-3p agataTGTATAGaaaatgt
 15
 CUAUACAA m7a Created -0.205000 -0.205000 -0.410000
hsa-let-7f-2-3p agataTGTATAGaaaatgt
 0 CUAUACAG m7a Created NA NA No effect
hsa-let-7g-3p agataTGTACAGaaaatgt
 0 CUGUACAG m7a Disrupted NA NA 0.210000
hsa-miR-1284 agataTGTATAGAaaatgt
 0 UCUAUACA m8a Created no TS -0.195000 -0.230000
hsa-miR-3686 agatatgTACAGAaaatgt
 12
 AUCUGUAA m6b Disrupted -0.046000 0.007000 0.320000
hsa-miR-4482-3p agatatgtATAGAAAatgt
 5
 UUUCUAUU m7a Created 0.008000 0.045000 -0.060000
hsa-miR-4652-3p agatatgtACAGAAaatgt
 12
 GUUCUGUU m6b Disrupted -0.072000 -0.059000 No effect
hsa-miR-493-5p agatATGTACAgaaaatgt
 9
 UUGUACAU m7b Disrupted -0.100000 no TS 0.230000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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