SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_181486
Gene Symbol: TBX5
Description: Homo sapiens T-box 5 (TBX5), transcript variant 1, mRNA.
Gene Location: chr12(-):114791734-114843889
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr12:g.114354080C>T COSN14477451 8057700 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr12:g.114354253T>C COSN8585404 J65_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-320a aagAGCTTTTaattttatt
 0 AAAAGCUG m7a (m7a->m6b) NA NA No effect
hsa-miR-320b aagAGCTTTTaattttatt
 0 AAAAGCUG m7a (m7a->m6b) NA NA No effect
hsa-miR-320c aagAGCTTTTaattttatt
 0 AAAAGCUG m7a (m7a->m6b) NA NA No effect
hsa-miR-320d aagAGCTTTTaattttatt
 0 AAAAGCUG m7a (m7a->m6b) NA NA No effect
hsa-miR-4429 aagAGCTTTTaattttatt
 0 AAAAGCUG m7a (m7a->m6b) NA NA No effect

Mutation Mutation ID Sample Name Cancer Type
chr12:g.114354460G>A COSN14507629 8070208 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4710 tgatatCTCACCaaagaaa
 0 GGGUGAGG m6b Created no TS -0.126000 -0.290000
hsa-miR-4792 tgatatCTCACCaaagaaa
 0 CGGUGAGC m6b Created no TS -0.133000 -12.980000
hsa-miR-9-5p tgatatctcACCAAAGAaa
 8
 UCUUUGGU m8a (m7a->m8a) -0.029000 -0.137000 -0.250000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.114354932T>C COSN8585405 308_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4717-3p cctctgCCATGTGatgttt
 13
 ACACAUGG m7b Disrupted -0.477000 -0.284000 -0.040000


Mutation Mutation ID Sample Name Cancer Type
chr12:g.114354962C>A COSN8585406 J30_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr12:g.114354963C>T COSN5931041 RK119_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3125 cacgtTTCCTCTtgactaa
 2
 UAGAGGAA m7b Created -0.190000 -0.300000 -2.310000
hsa-miR-3916 cacgtTTCCTCTTgactaa
 2
 AAGAGGAA m8a Created -0.218000 -0.318000 -0.120000
hsa-miR-4496 cacGTTTCCTCttgactaa
 2
 GAGGAAAC m8a Created -0.055000 -0.109000 -3.120000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.114355011G>A COSN8585407 J30_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2276 tgtaCTTGCAGgattccct
 0 UCUGCAAG m7b Created no TS -0.164000 No effect
hsa-miR-4772-3p tgtacTTGCAGGattccct
 0 CCUGCAAC m7a Created NA NA No effect

Mutation Mutation ID Sample Name Cancer Type
chr12:g.114355105A>G COSN5831340 SS6003131 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-382-3p taataAATGATaatatatt
 4
 AAUCAUUC m6b Disrupted -0.043000 0.033000 0.030000
hsa-miR-4729 taATAAATGAtaatatatt
 4
 UCAUUUAU m8a (m8a->m7b) -0.121000 -0.073000 -0.440000
hsa-miR-4795-3p taataaatgATAATATatt
 17
 AUAUUAUU m7a (m7a->m6a) 0.019000 0.026000 0.010000
hsa-miR-556-3p taataaatGGTAATATatt
 12
 AUAUUACC m8a Created -0.045000 -0.258000 -3.870000
hsa-miR-5696 taaTAAATGAtaatatatt
 4
 CUCAUUUA m7b (m7b->m6c) -0.097000 0.024000 0.020000
hsa-miR-656 taataaatgATAATATatt
 18
 AAUAUUAU m7b (m7b->m6b) -0.045000 0.019000 -0.450000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.114355468G>T COSN14669917 8069168 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1248 aaagagagAGAAGGagaga
 2
 ACCUUCUU m6b Disrupted -0.084000 no TS 5.240000
hsa-miR-3675-3p aaagAGAGATaaggagaga
 0 CAUCUCUA m6b Created no TS -0.104000 -5.960000
hsa-miR-4768-5p aaagaGAGAGAAggagaga
 0 AUUCUCUC m7b Disrupted -0.160000 -0.031000 -0.150000
hsa-miR-942 aaagagAGAGAAGgagaga
 2
 UCUUCUCU m7b Disrupted -0.095000 no TS 1.240000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.114355508C>T COSN2381451 TCGA-AX-A05S-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5093 cacaacagaCATTTCCTag
 2
 AGGAAAUG m8a (m8a->m7a) -0.162000 no TS -0.010000
hsa-miR-654-3p cacaaCAGACATttcctag
 0 UAUGUCUG m7b Disrupted -0.195000 no TS 0.280000
hsa-miR-5093 cacaacagaCATTTCCTag
 0 AGGAAAUG m8a (m8a->m7a) -0.162 no TS -0.01
hsa-miR-654-3p cacaaCAGACATttcctag
 0 UAUGUCUG m7b Disrupted -0.195 no TS 0.28

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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