SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_000192 |
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Gene Symbol: | TBX5 |
Description: | Homo sapiens T-box 5 (TBX5), transcript variant 1, mRNA. |
Gene Location: | chr12(-):114791734-114846247 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.114354080C>T | COSN14477451 | 8057700 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.114354253T>C | COSN8585404 | J65_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-320a |
aagAGCTTTTaattttatt |
0 | AAAAGCUG | m7a | (m7a->m6b) | NA | NA | No effect |
hsa-miR-320b |
aagAGCTTTTaattttatt |
0 | AAAAGCUG | m7a | (m7a->m6b) | NA | NA | No effect |
hsa-miR-320c |
aagAGCTTTTaattttatt |
0 | AAAAGCUG | m7a | (m7a->m6b) | NA | NA | No effect |
hsa-miR-320d |
aagAGCTTTTaattttatt |
0 | AAAAGCUG | m7a | (m7a->m6b) | NA | NA | No effect |
hsa-miR-4429 |
aagAGCTTTTaattttatt |
0 | AAAAGCUG | m7a | (m7a->m6b) | NA | NA | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.114354460G>A | COSN14507629 | 8070208 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4710 |
tgatatCTCACCaaagaaa |
0 | GGGUGAGG | m6b | Created | no TS | -0.126000 |
-0.290000 |
hsa-miR-4792 |
tgatatCTCACCaaagaaa |
0 | CGGUGAGC | m6b | Created | no TS | -0.133000 |
-12.980000 |
hsa-miR-9-5p |
tgatatctcACCAAAGAaa |
8 |
UCUUUGGU | m8a | (m7a->m8a) | -0.029000 | -0.137000 |
-0.250000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.114354932T>C | COSN8585405 | 308_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4717-3p |
cctctgCCATGTGatgttt |
13 |
ACACAUGG | m7b | Disrupted | -0.477000 | -0.284000 |
-0.040000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.114354962C>A | COSN8585406 | J30_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.114354963C>T | COSN5931041 | RK119_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3125 |
cacgtTTCCTCTtgactaa |
2 |
UAGAGGAA | m7b | Created | -0.190000 | -0.300000 |
-2.310000 |
hsa-miR-3916 |
cacgtTTCCTCTTgactaa |
2 |
AAGAGGAA | m8a | Created | -0.218000 | -0.318000 |
-0.120000 |
hsa-miR-4496 |
cacGTTTCCTCttgactaa |
2 |
GAGGAAAC | m8a | Created | -0.055000 | -0.109000 |
-3.120000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.114355011G>A | COSN8585407 | J30_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-2276 |
tgtaCTTGCAGgattccct |
0 | UCUGCAAG | m7b | Created | no TS | -0.164000 | No effect |
hsa-miR-4772-3p |
tgtacTTGCAGGattccct |
0 | CCUGCAAC | m7a | Created | NA | NA | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.114355105A>G | COSN5831340 | SS6003131 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-382-3p |
taataAATGATaatatatt |
4 |
AAUCAUUC | m6b | Disrupted | -0.043000 | 0.033000 |
0.030000 |
hsa-miR-4729 |
taATAAATGAtaatatatt |
4 |
UCAUUUAU | m8a | (m8a->m7b) | -0.121000 | -0.073000 |
-0.440000 |
hsa-miR-4795-3p |
taataaatgATAATATatt |
17 |
AUAUUAUU | m7a | (m7a->m6a) | 0.019000 | 0.026000 |
0.010000 |
hsa-miR-556-3p |
taataaatGGTAATATatt |
12 |
AUAUUACC | m8a | Created | -0.045000 | -0.258000 |
-3.870000 |
hsa-miR-5696 |
taaTAAATGAtaatatatt |
4 |
CUCAUUUA | m7b | (m7b->m6c) | -0.097000 | 0.024000 |
0.020000 |
hsa-miR-656 |
taataaatgATAATATatt |
18 |
AAUAUUAU | m7b | (m7b->m6b) | -0.045000 | 0.019000 |
-0.450000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.114355468G>T | COSN14669917 | 8069168 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1248 |
aaagagagAGAAGGagaga |
2 |
ACCUUCUU | m6b | Disrupted | -0.084000 | no TS |
5.240000 |
hsa-miR-3675-3p |
aaagAGAGATaaggagaga |
0 | CAUCUCUA | m6b | Created | no TS | -0.104000 |
-5.960000 |
hsa-miR-4768-5p |
aaagaGAGAGAAggagaga |
0 | AUUCUCUC | m7b | Disrupted | -0.160000 | -0.031000 |
-0.150000 |
hsa-miR-942 |
aaagagAGAGAAGgagaga |
2 |
UCUUCUCU | m7b | Disrupted | -0.095000 | no TS |
1.240000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.114355508C>T | COSN2381451 | TCGA-AX-A05S-01 | [endometrium][NS][carcinoma][endometrioid_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-5093 |
cacaacagaCATTTCCTag |
2 |
AGGAAAUG | m8a | (m8a->m7a) | -0.162000 | no TS |
-0.010000 |
hsa-miR-654-3p |
cacaaCAGACATttcctag |
0 | UAUGUCUG | m7b | Disrupted | -0.195000 | no TS |
0.280000 |
hsa-miR-5093 |
cacaacagaCATTTCCTag |
0 | AGGAAAUG | m8a | (m8a->m7a) | -0.162 | no TS |
-0.01 |
hsa-miR-654-3p |
cacaaCAGACATttcctag |
0 | UAUGUCUG | m7b | Disrupted | -0.195 | no TS |
0.28 |