SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001169118
Gene Symbol: STIM2
Description: Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 3, mRNA.
Gene Location: chr4(+):26862312-27027003
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr4:g.27023052A>C COSN8870279 SNUH_G15_S1 [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1275 ttaTCCCCCACcctccact
1
GUGGGGGA m8a Disrupted -0.267000 no TS 3.090000
hsa-miR-1914-3p ttatcccccCCCCTCCact
0 GGAGGGGU m7a (m6b->m7a) NA NA -12.240000
hsa-miR-4447 ttatCCCCCACCctccact
1
GGUGGGGG m8a Disrupted -0.322000 no TS 2.900000
hsa-miR-4472 ttatCCCCCACCctccact
1
GGUGGGGG m8a Disrupted -0.322000 no TS 2.010000
hsa-miR-4525 ttATCCCCCCccctccact
1
GGGGGGAU m8a (m7a->m8a) -0.469000 -0.244000 0.160000
hsa-miR-4665-5p ttaTCCCCCAccctccact
1
CUGGGGGA m7b (m7b->m6b) -0.267000 no TS 9.090000
hsa-miR-92a-2-5p ttatcCCCCACCCtccact
0 GGGUGGGG m8a Disrupted -0.559000 -0.298000 0.090000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.27023240C>T COSN1295220 HCC102T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3607-3p gacagTTTACAGTcatttc
17
ACUGUAAA m8a Disrupted -0.102000 no TS 0.010000
hsa-miR-625-3p gacagttTATAGTCatttc
0 GACUAUAG m7a Created NA NA No effect
hsa-miR-943 gacagtttACAGTCAtttc
11
CUGACUGU m7b Disrupted -0.265000 no TS No effect
hsa-miR-3607-3p gacagTTTACAGTcatttc
17
ACUGUAAA m8a Disrupted -0.102 no TS 0.01
hsa-miR-625-3p gacagttTATAGTCatttc
0 GACUAUAG m7a Created NA NA No effect
hsa-miR-943 gacagtttACAGTCAtttc
0 CUGACUGU m7b Disrupted -0.265 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr4:g.27023567A>C COSN7482481 8051900 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-138-1-3p gggtttttAAGTAGaacct
19
GCUACUUC m6b Disrupted -0.056000 no TS 0.010000
hsa-miR-302a-5p gggttTTTAAGTagaacct
0 ACUUAAAC m7a Disrupted NA NA 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.27024033G>A COSN9786795 C0086T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4662a-3p gtgtaagCTATCTTgttgc
0 AAAGAUAG m7b Created no TS 0.018000 0.130000
hsa-miR-5579-3p gtgTAAGCTAtcttgttgc
0 UUAGCUUA m7b (m6b->m7b) no TS -0.023000 -1.560000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.27024232G>A COSN2020239 RK056_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4714-3p taaattggTAGGTTGtata
0 CCAACCUA m7b Created no TS -0.049000 -0.060000
hsa-miR-4714-3p taaattggTAGGTTGtata
0 CCAACCUA m7b Created no TS -0.049 -0.06

Mutation Mutation ID Sample Name Cancer Type
chr4:g.27024900A>G COSN2020240 RK006_C02 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-518a-5p gaaCTTTGCAGttggatga
1
CUGCAAAG m8a Disrupted -0.141000 no TS 0.270000
hsa-miR-527 gaaCTTTGCAGttggatga
1
CUGCAAAG m8a Disrupted -0.141000 no TS 0.270000
hsa-miR-518a-5p gaaCTTTGCAGttggatga
1
CUGCAAAG m8a Disrupted -0.141 no TS 0.27
hsa-miR-527 gaaCTTTGCAGttggatga
1
CUGCAAAG m8a Disrupted -0.141 no TS 0.27

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table

Location SNP ID Ancestral
Allele
Allele miR ID Conservation miRSite FuncClass Validation context+
score change
27023068 rs202033434 - - hsa-miR-92a-2-5p
2
CCCCACCtttttt
Unknown
N
0.005
T

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