SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_030964 |
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Gene Symbol: | SPRY4 |
Description: | Homo sapiens sprouty homolog 4 (Drosophila) (SPRY4), transcript variant 2, mRNA. |
Gene Location: | chr5(-):141689991-141704620 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr5:g.142310516T>C | COSN2073655 | RK004_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4719 |
tcttctgTTTGTGAagaaa |
21 |
UCACAAAU | m7a | Disrupted | -0.071000 | no TS | No effect |
hsa-miR-4719 |
tcttctgTTTGTGAagaaa |
0 | UCACAAAU | m7a | Disrupted | -0.071 | no TS | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr5:g.142310830T>C | COSN7877952 | 8069321 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-106a-5p |
tgacaaGCACTTTTgtgcc |
15 |
AAAAGUGC | m8a | Created | -0.016000 | -0.097000 |
-0.360000 |
hsa-miR-106b-5p |
tgacaaGCACTTTtgtgcc |
15 |
UAAAGUGC | m7b | Created | -0.016000 | -0.097000 |
-0.140000 |
hsa-miR-17-5p |
tgacaaGCACTTTtgtgcc |
15 |
CAAAGUGC | m7b | Created | -0.016000 | -0.097000 |
-0.360000 |
hsa-miR-20a-5p |
tgacaaGCACTTTtgtgcc |
15 |
UAAAGUGC | m7b | Created | -0.007000 | -0.088000 |
-0.600000 |
hsa-miR-20b-5p |
tgacaaGCACTTTtgtgcc |
15 |
CAAAGUGC | m7b | Created | -0.007000 | -0.088000 |
-0.520000 |
hsa-miR-302a-3p |
tgacaAGCACTTttgtgcc |
8 |
UAAGUGCU | m7b | Created | -0.130000 | -0.239000 |
-0.050000 |
hsa-miR-302b-3p |
tgacaAGCACTTttgtgcc |
8 |
UAAGUGCU | m7b | Created | -0.130000 | -0.239000 |
-0.330000 |
hsa-miR-302c-3p |
tgacaAGCACTTttgtgcc |
8 |
UAAGUGCU | m7b | Created | -0.130000 | -0.239000 |
-0.200000 |
hsa-miR-302d-3p |
tgacaAGCACTTttgtgcc |
8 |
UAAGUGCU | m7b | Created | -0.130000 | -0.239000 |
-0.020000 |
hsa-miR-302e |
tgacaAGCACTTttgtgcc |
8 |
UAAGUGCU | m7b | Created | -0.130000 | -0.230000 |
-0.030000 |
hsa-miR-372 |
tgacaAGCACTTTtgtgcc |
8 |
AAAGUGCU | m8a | Created | -0.149000 | -0.258000 | No effect |
hsa-miR-373-3p |
tgacaAGCACTTttgtgcc |
8 |
GAAGUGCU | m7b | Created | -0.130000 | -0.221000 | No effect |
hsa-miR-519d |
tgacaaGCACTTTtgtgcc |
15 |
CAAAGUGC | m7b | Created | -0.053000 | -0.116000 | No effect |
hsa-miR-520a-3p |
tgacaAGCACTTTtgtgcc |
8 |
AAAGUGCU | m8a | Created | -0.140000 | -0.240000 |
-0.010000 |
hsa-miR-520b |
tgacaAGCACTTTtgtgcc |
8 |
AAAGUGCU | m8a | Created | -0.130000 | -0.230000 |
-0.070000 |
hsa-miR-520c-3p |
tgacaAGCACTTTtgtgcc |
8 |
AAAGUGCU | m8a | Created | -0.130000 | -0.230000 |
-0.030000 |
hsa-miR-520d-3p |
tgacaAGCACTTTtgtgcc |
8 |
AAAGUGCU | m8a | Created | -0.149000 | -0.249000 |
-0.040000 |
hsa-miR-520e |
tgacaAGCACTTTtgtgcc |
8 |
AAAGUGCU | m8a | Created | -0.130000 | -0.221000 | No effect |
hsa-miR-520f |
tgacAAGCACTTttgtgcc |
9 |
AAGUGCUU | m8a | Created | -0.131000 | -0.239000 |
-0.430000 |
hsa-miR-526b-3p |
tgacaaGCACTTTtgtgcc |
15 |
GAAAGUGC | m7b | Created | -0.035000 | -0.107000 |
-0.370000 |
hsa-miR-548t-5p |
tgacaagCACTTTTGtgcc |
0 | CAAAAGUG | m8a | Created | no TS | 0.041000 | No effect |
hsa-miR-636 |
tgaCAAGCACttttgtgcc |
0 | UGUGCUUG | m7b | (m6c->m7b) | no TS | -0.154000 |
-0.020000 |
hsa-miR-93-5p |
tgacaaGCACTTTtgtgcc |
15 |
CAAAGUGC | m7b | Created | -0.025000 | -0.106000 |
-0.020000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr5:g.142310980G>A | COSN6583901 | ICGC_MB110 | [central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3126-3p |
ccagaacCCAGATGactgt |
0 | CAUCUGGC | m7a | Created | NA | NA |
0.540000 |
hsa-miR-4507 |
ccagAACCCAGatgactgt |
0 | CUGGGUUG | m7a | Created | NA | NA | No effect |
hsa-miR-452-3p |
ccagaaccCAGATGActgt |
0 | CUCAUCUG | m7b | Created | 0.087000 | 0.074000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr5:g.142311254C>T | COSN14963469 | CHC205T | [liver][NS][carcinoma][hepatocellular_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-298 |
cagcgCTTCTGCgagcacc |
1 |
AGCAGAAG | m7b | Created | -0.023000 | 0.022000 |
-0.110000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr5:g.142311677A>G | COSN6865645 | RK128_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4655-3p |
aaggagCGAGGGaaccatc |
0 | ACCCUCGU | m6b | Created | no TS | -0.129000 |
-0.090000 |
hsa-miR-642a-5p |
aaggagcGAGGGAaccatc |
0 | GUCCCUCU | m6b | Created | no TS | 0.003000 |
-0.010000 |
hsa-miR-642b-5p |
aaggagcgAGGGAACCatc |
0 | GGUUCCCU | m8a | Created | no TS | 0.030000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr5:g.142311935C>A | 0_231 | Prostate cancer | ||||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3650 |
cacacACACACCTacccca |
5 |
AGGUGUGU | m8a | Created | 0.121 | 0.091 |
-0.6 |
hsa-miR-4455 |
cacaCACACCCctacccca |
5 |
AGGGUGUG | m7b | Disrupted | -0.062 | -0.018 |
0.67 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr5:g.142311962T>C | COSN6510501 | HX30T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-147a |
agctgtgtaCACACACaca |
0 | GUGUGUGG | m7a | (m6a->m7a) | NA | NA |
-0.180000 |
hsa-miR-223-5p |
agctgtgtATACACacaca |
0 | CGUGUAUU | m6b | Disrupted | 0.087000 | no TS | No effect |
hsa-miR-3177-5p |
agctgTGTACACAcacaca |
0 | UGUGUACA | m8a | Created | no TS | 0.063000 |
-0.040000 |
hsa-miR-466 |
agcTGTGTATacacacaca |
2 |
AUACACAU | m7a | (m7a->m6b) | 0.135000 | 0.135000 | No effect |
hsa-miR-4789-5p |
agctGTGTATACacacaca |
0 | GUAUACAC | m8a | Disrupted | 0.033000 | -0.018000 |
0.210000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr5:g.142312094C>T | COSN9408793 | AOCS-111-1-X | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4251 |
tctgcgaggTCTCAGaact |
0 | CCUGAGAA | m6b | Created | -0.028000 | 0.055000 |
-0.020000 |
hsa-miR-4329 |
tctgcgagGTCTCAGaact |
0 | CCUGAGAC | m7b | Created | no TS | 0.086000 |
-0.010000 |
hsa-miR-4649-3p |
tctgcgagGCCTCAGAact |
0 | UCUGAGGC | m8a | Disrupted | 0.035000 | 0.006000 |
-0.760000 |
hsa-miR-769-5p |
tctgcgAGGTCTCAgaact |
0 | UGAGACCU | m8a | Created | no TS | 0.064000 |
-0.150000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr5:g.142313089T>C | COSN6865648 | RK210_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr5:g.142313319G>A | COSN195736 | PD4199a | [NS][NS][NS][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-151a-3p |
aatgAGTCTAaggctgtgg |
0 | CUAGACUG | m6b | Created | no TS | -0.020000 |
-1.810000 |
hsa-miR-4494 |
aatgAGTCTGaggctgtgg |
16 |
CCAGACUG | m6b | Disrupted | -0.025000 | no TS |
0.420000 |
hsa-miR-499b-5p |
aatgAGTCTGaggctgtgg |
16 |
ACAGACUU | m6b | Disrupted | -0.028000 | no TS |
10.830000 |
hsa-miR-151a-3p |
aatgAGTCTAaggctgtgg |
0 | CUAGACUG | m6b | Created | no TS | -0.02 |
-1.81 |
hsa-miR-4494 |
aatgAGTCTGaggctgtgg |
0 | CCAGACUG | m6b | Disrupted | -0.025 | no TS |
0.42 |
hsa-miR-499b-5p |
aatgAGTCTGaggctgtgg |
0 | ACAGACUU | m6b | Disrupted | -0.028 | no TS |
10.83 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr5:g.142313511C>A | COSN5069985 | HX19T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3202 |
ttctCCCTTCCAactgcat |
0 | UGGAAGGG | m8a | Disrupted | -0.725000 | -0.468000 |
4.760000 |
hsa-miR-4533 |
ttctcCCTTCCAactgcat |
0 | UGGAAGGA | m7a | Disrupted | -0.072000 | -0.014000 |
0.020000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr5:g.142313836G>T | COSN6510502 | HX33T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-25-5p |
cctccCTCCGCCccccccc |
0 | AGGCGGAG | m7b | Disrupted | -0.157000 | no TS |
0.160000 |
hsa-miR-3180 |
cctccctCCGCCCCccccc |
0 | UGGGGCGG | m7b | Disrupted | -0.423000 | -0.200000 |
3.900000 |
hsa-miR-3180-3p |
cctccctCCGCCCCccccc |
0 | UGGGGCGG | m7b | Disrupted | -0.432000 | -0.200000 |
3.650000 |
hsa-miR-3196 |
cctccctCCGCCCCccccc |
0 | CGGGGCGG | m7b | Disrupted | -0.423000 | -0.200000 |
2.830000 |
hsa-miR-4488 |
cctccctcCGCCCCCcccc |
0 | AGGGGGCG | m7b | Disrupted | -0.154000 | no TS |
3.210000 |
hsa-miR-4697-5p |
cctccctcCGCCCCCcccc |
0 | AGGGGGCG | m7b | Disrupted | -0.136000 | no TS |
0.170000 |
hsa-miR-4723-5p |
cctccctcCTCCCCCcccc |
0 | UGGGGGAG | m7b | Created | no TS | -0.127000 |
-0.100000 |
hsa-miR-4779 |
cctCCCTCCTccccccccc |
4 |
UAGGAGGG | m7b | (m6c->m7b) | -0.089000 | -0.169000 |
-0.370000 |
hsa-miR-5698 |
cctccctcCTCCCCCcccc |
0 | UGGGGGAG | m7b | Created | no TS | -0.108000 |
-0.010000 |
hsa-miR-658 |
cctcCCTCCGCCccccccc |
0 | GGCGGAGG | m8a | Disrupted | -0.166000 | no TS |
3.060000 |
hsa-miR-765 |
cctccCTCCTCCccccccc |
0 | UGGAGGAG | m7b | Created | no TS | -0.055000 |
-0.850000 |